A year-long measles outbreak in Ontario was concentrated in closely connected, historically under-vaccinated communities and contributed to Canada losing its measles elimination status. Researchers warn that immunity gaps, cross-border social networks and declining trust in vaccination can quickly undermine decades of disease control.
Why can a second dengue infection be more dangerous than the first? A controlled human challenge study shows how pre-existing antibodies can either boost viral replication or help restrain it, offering new clues for designing vaccines that protect against all four dengue virus types.
Fungi may be helping antibiotic resistance genes survive during livestock manure composting. Researchers found that suppressing fungal activity weakened microbial networks and increased the removal of resistance genes, suggesting that fungi could play an overlooked role in the environmental spread of antimicrobial resistance.
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An isolated mountain range in Colombia remains free of the deadly chytrid fungus that has devastated amphibians elsewhere in the Americas. But researchers found a highly virulent variant only about 20 kilometres away, creating a rare opportunity to protect a rich amphibian community before the disease arrives.
Translucent patches in flower petals can alter the light and heat inside blooms, creating tiny microclimates that shape the microbes living there. Researchers found that warmer flowers tended to harbour fewer microbes, suggesting that petal structure may influence floral microbiomes and potentially plant-pollinator interactions.
The immune system somehow tolerates trillions of gut bacteria without constantly attacking them. Researchers have now identified a gene-regulatory pathway that helps regulatory T cells maintain this peace, with defects in the pathway triggering severe inflammation and autoimmunity in mice.
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