Scientists have demonstrated that combining lifespan engineering strategies with metabolic pathway optimization in Saccharomyces cerevisiaeenables highly efficient sclareol biosynthesis, marking an advance in improving microbial production through lifespan engineering.
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
GSK and the Fleming Initiative have announced six major new research programmes, called ‘Grand Challenges’ which harness some of the best scientific expertise and the latest technologies, including advanced AI, to find new ways to slow the progress of antimicrobial resistance (AMR).
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Researchers used CRISPR to increase a fungus’s production efficiency and cut its production-related environmental impact by as much as 61%—all without adding any foreign DNA. The genetically tweaked fungus tastes like meat and is easier to digest than its naturally occurring counterpart.
A machine learning framework can distinguish molecules made by biological processes from those formed through non-biological processes and could be used to analyze samples returned by current and future planetary missions.
A new review explores how bifidobacterium, a common probiotic found in the gut, may contribute to cancer prevention and therapy. The authors highlight the growing importance of gut health in cancer treatment and shed light on how bifidobacterium could complement standard cancer therapies.
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