Scientists have uncovered how Pseudomonas aeruginosa, a major multidrug-resistant superbug, helps block antibiotics from entering its cells. The study identifies two proteins that act like plugs inside a membrane channel, revealing a potential new target for treatments designed to weaken bacterial defenses.
Antibiotic resistance is becoming an increasing challenge for Vietnam’s vast pangasius catfish industry, where farmers often have few practical alternatives when treatments stop working. A new £2.4 million project will bring scientists, farmers and policymakers together to develop more sustainable ways to control disease and reduce reliance on antibiotics.
Why do some hantaviruses jump from rodents to humans while others remain largely confined to wildlife? A new study will combine viral genetics, climate data and wildlife ecology to uncover the conditions that drive spillover and help identify where future outbreaks are most likely to emerge.
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Testing sputum samples in small groups could nearly double access to rapid tuberculosis diagnosis without doubling costs. The largest study of pooled TB testing found that the approach cut molecular test cartridge use by 51%, helping inform new WHO guidance for resource-constrained settings.
Deep-sea clams living at cold seeps survive in an environment where their main energy source can rise and fall dramatically. New research shows that the clams and their bacterial partners respond together, switching metabolic pathways, adjusting symbiont populations and reallocating resources to remain stable under changing conditions.
Researchers have built a centimetre-scale ‘society on a chip’ that recreates how viruses spread through structured populations. By changing cell density, susceptibility and movement, the platform can mimic transmission, social distancing and even herd-immunity-like effects in real time.
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