Researchers have traced step by step how herpes simplex virus 1 infects the multiple layers of skin cells. Using human hair-bearing skin organoids as a model, the researchers mapped how the virus spreads and which signaling molecules cells release to their neighbors upon being infected.
In an earlier study, researchers demonstrated that albumin, the most abundant protein in human blood, can enhance the pathogenic properties of Candida albicans. It has now been revealed that this protein can also trigger an excessive inflammatory response.
A $3.67 million NIH-funded project is developing antiviral compounds that could block alphavirus replication and help protect the brain from severe infection. Researchers will also use blood-brain-barrier-on-a-chip models to test whether early treatment can reduce neurological damage.
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A new study has revealed how coral-associated bacteria help corals withstand extreme heat by producing steroid hormones that strengthen their immune response. Endozoicomonas, a group of bacteria commonly associated with corals worldwide, produce steroid hormones including testosterone and progesterone when temperatures rise.
A study investigated the gut microbiome of 75 vegans and 75 omnivorous Danes. The researchers initially expected the vegan group to have the healthiest gut microbiome across all parameters, but found one notable weakness: gut bacterial diversity was, on average, lower among vegans than among omnivores.
A handful of soil holds a crowded world of bacteria, fungi and other organisms. Scientists can collect their DNA, but much of it remains difficult to identify. Now, researchers have developed an artificial intelligence tool that recognizes bacterial DNA in tiny genetic fragments, making it faster and easier to study the complex communities living in soil.
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