All Research News articles
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Researchers discovered replication hubs for human norovirus
Researchers have reported the discovery of replication hubs for human norovirus, which could lead to designing antiviral drugs to prevent, control or treat these infections.
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Seasonal flu vaccine study reveals host genetics’ role in vaccine response
Scientists have found that influenza subtype-bias is primarily driven by host genetics, particularly major histocompatibility complex (MHC) class-II polymorphisms, with prior exposure playing a secondary role.
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Potentially harmful bacteria slip through antimicrobial showerheads
Researchers report that antimicrobial silver-containing showerheads are no ’silver bullet’. In real-world showering conditions, most microbes aren’t exposed to the silver long enough to be killed.
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Evolutionary study reveals the toxic reach of disease-causing bacteria across the plant kingdom
The capacity of bacteria to spread disease across the plant kingdom may be much more widespread than previously suspected, according to a comparative evolutionary analysis, using the diversity of Pseudomonas syringae bacteria.
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Capybaras found dead from rabies on island in Brazil
The viral rabies strain found in the dead animals on Anchieta Island in Ubatuba was the variant transmitted by vampire bats, which probably fed on the capybaras’ blood at a time of habitat disturbance.
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The surprising role of gut infection in Alzheimer’s disease
A new study implicates link between a common virus and the disease, which travels from the gut to the brain and may be a target for antiviral treatments.
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Nature’s instructions: How fungi make a key medicinal molecule
Scientists outline how they deciphered nature’s own instructions — namely, the genes of the mold Penicillium citrinum — to discover a previously unreported enzyme that catalyzes the creation of cyclopentachromone-containing compounds.
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The role of understudied dysfunctional immune cells in severe COVID-19: new research
A new study focuses on understanding how ‘notoriously understudied’ immune cells behave abnormally in patients with severe COVID-19 and provides insights into mechanism behind COVID-19 disease progression.
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Connectivity loss in pond networks threatens microbial biodiversity
A recent study explored the effects of connectivity loss within pond networks, using an outdoor experimental setup of artificial ponds (mesocosms).
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Study reveals the hidden genomic evolution of brown algae - and how bacteria and viruses helped
A groundbreaking study has unveiled the evolutionary journey of brown algae through a comprehensive genomic analysis of 44 species, including key evolutionary milestones, such as the transition from unicellular to multicellular forms.
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Flagella-free survival: How bacteria evolve by shedding their ‘wheels’
New research reveals that bacteria can evolve by losing their flagella, the structures responsible for movement.
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‘Unbreakable’ Lassa vaccine shows promising results
A live-attenuated vaccine candidate against Lassa virus completely protected guinea pigs exposed to an otherwise lethal dose of the virus, researchers have reported.
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Phytochromes: The ‘eyes’ that enable microalgae to find their way in the depths
By studying the light perception process of diatoms, a group of phytoplankton, scientists have discovered that these microalgae use light variation sensors which are codified in their genomes: phytochromes.
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Application of heavy-ion irradiation mutagenesis to improve the production efficiency of the antifungal drug micafungin
Scientists have used heavy-ion irradiation to improve efforts to produce the semisynthetic echinocandin antifungal agent micafungin which derives from fungal natural product FR901379 produced by Coleophoma empetri.
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Discovery of β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition in Serratia marcescens
A new study has identified β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens.
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Scientists offer user manual for yeast’s genetic switches
Scientists have found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production using yeast.
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Diarrheal diseases remain a leading killer for children under 5, adults 70+
A new global study reports a 60% drop in global mortality from diarrheal diseases, but children and the elderly still have the highest death rates, particularly in sub-Saharan Africa and South Asia.
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New discovery provides hope in fighting drug-resistant malaria
Researchers have described how they may have found a new target in Plasmodium falciparum, the deadliest malaria parasite: a cholesterol-managing protein called PfNCR1.
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Living in the deep, dark, slow lane: first global appraisal of microbiomes in earth’s subsurface environments
A new study reveals astonishingly high microbial diversity in some of the Earth’s deepest, darkest subsurface environments, including gold mines, in aquifers and deep boreholes in the seafloor.
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After lockdown, immune system reacts more strongly to viruses and bacteria
The lockdowns during the COVID-19 pandemic had a significant impact on people’s immune response to microorganisms. During the lockdown, inflammation level in the body was low, but afterwards, the immune system reacted more intensely to viruses and bacteria.