All Viruses articles
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New therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens the door to new treatments.
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Expedition confirms spread of highly pathogenic avian influenza virus in the Weddell Sea
The CSIC-UNESPA scientific expedition monitoring the presence of the highly pathogenic avian influenza virus (HPAI H5N1) in Antarctica has confirmed the presence of the virus in all species detected on six islands in the Weddell Sea.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Fungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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Could microRNAs help us understand why different birds react differently to being infected with bird flu?
Since microRNA was found to have a role in cell protein production, a connection between microRNA and birds infected with bird flu has been found in ruddy turnstones, which has significance with respect to the spread of bird flu due to their long distance flights.
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Mass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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Scientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Eliminating HIV funding program would lead to >600k deaths in South Africa alone: warning
A new analysis finds that eliminating PEPFAR would lead to 601,000 HIV-related deaths, 565,000 new HIV infections, and would increase population-level healthcare expenditure by $1.7 billion over the next decade in South Africa alone.
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Evolutionary tradeoffs: Research explores the role of iron levels in COVID-19 infections
Iron has been found to be essential to both human physiology and pathogen replication. The richer the iron availability, the more likely to be susceptible to infections, such as COVID-19. A balance of iron levels is thus critical for homeostasis and preventing pathogenic infections.
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Killing H5N1 in waste milk — an alternative to pasteurization
Researchers have found that acidification can kill H5N1 in waste milk, providing dairy farmers an affordable, easy-to-use alternative to pasteurization of waste milk.
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Researchers explore Spanish flu’s impact on Appalachia
A new book examines how the 1918 influenza pandemic disproportionately impacted Appalachian communities, exacerbating long-standing health disparities. Those included limited health care access, poor working conditions and systemic poverty.
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Researchers unlock new potential porcine virus treatment
Researchers have identified a novel small molecule for the development of preventative treatment for porcine reproductive and respiratory syndrome virus (PRRSV).
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Researchers review strategies for the modification of vaccinia virus towards a better vaccine vector
A new review delineates the commonly targeted viral genes for attenuation during vaccinia virus (VACV) vector modification and provides an overview of the progress in VACV-vectored vaccine development.
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New modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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Mpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
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Unravelling the complex role of climate in dengue dynamics
A research recently shows that specific climates of the region could greatly influence the change in disease dynamics of dengue fever and other climate-related infectious diseases, through analyzing the casual relationships between both.
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Reemergence of dengue serotype 3 may increase severity of outbreaks of the disease in Brazil
From the genomic and epidemiological surveillance of the circulating dengue virus strains, a more severe dengue epidemic may occur in Brazil, due to the re-establishment of dengue virus serotype 3 (DENV-3) and persists alongside with the serotype 1 and 2 (DENV-1 and DENV-2).