All Viruses articles
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Mpox could become a serious global threat, scientists warn
Mpox has the potential to become a significant global health threat if taken too lightly. Scientists highlight how mpox – traditionally spread from animals to humans – is now showing clear signs of sustained human-to-human transmission.
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MOPEVACLAS vaccine candidate for Lassa fever enters clinical trials
After more than 20 years of research on arenaviruses, researchers have developed an original vaccine platform known as MOPEVAC. A Phase Ia clinical trial is set to begin for the platform’s first vaccine candidate, which targets Lassa fever, a hemorrhagic fever responsible for thousands of deaths worldwide each year.
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Researchers develop machine learning model to predict virus reservoirs
A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans.
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AI learns to ‘speak’ genetic ‘dialect’ for future SARS-CoV-2 mutation prediction
Researchers have developed a new method to predict mutations in virus protein sequences called Deep Novel Mutation Search (DNMS), a type of artificial intelligence model that uses deep neural networks.
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Compelling data point to a single, unknown respiratory virus as cause of Kawasaki disease
New research strongly suggests that Kawasaki disease is caused by a single respiratory virus that is yet to be identified. Findings contradict the theory that many different pathogens or toxins could cause this disease that can lead to serious cardiac complications in young children.
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Only few disinfectants are capable of inactivating hepatitis A virus
Researchers tested nine different surface disinfectants against Hepatitis A virus. According to their findings, only two aldehyde-based products proved effective at inactivating HAV.
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mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the innate immune system
A study showed that vaccination of multiple mRNA-based COVID-19 vaccines could induce persistent epigenetic changes in innate immune cells, leading to long-term immune responses for SARS-CoV-2 and other pathogens.
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Researchers design genetic tools to develop vaccines more efficiently for African swine fever virus (ASFV)
A synthetic genomic-based reverse genetics tool has been developed for African swine fever virus (ASFV) that helps vaccine development to reduce the economic losses. The system may also be adapted to other emerging viral threats.
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Scientists zoom in on structure of still lethal Ebola virus
The first high-resolution visualisation of the Ebola virus nucleocapsid provides detailed insights into the interactions within the nucleocapsid complex, unveiling the relationship between molecular interactions and functional regulation.
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Proposed cuts to foreign aid could result in millions of HIV deaths, new modelling study estimates
New modelling analysis suggests that proposed funding cuts by major donor countries to foreign aid could undo decades of progress made to end HIV/AIDS as a public health threat and new infections and deaths could surge back to levels not seen since the early 2000s.
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How Zika virus knocks out our immune defenses
Scientists have made striking discoveries regarding the different infection mechanisms of Zika and dengue virus of the same viral family. These understandings pave the way for vaccine development to combat flaviviruses with similarities.
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Canada is slowest in reporting bird flu – but COVID shows we can do better
A global study was conducted to measure the reporting speed of pandemic-causing bird flu H5N1 in different countries, among which Canada surprisingly came in last, addressing the need for improvements in the current monitoring procedures.
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Researchers find live hantavirus is carried in various New Mexico small mammal species
A study was carried out to find out the reasons why human cases of the sin nombre hantavirus were concentrated in one particular region of New Mexico, even though the virus was found in 30 species of rodents and small mammals endemic to a different region.
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Hepatitis B: new rapid diagnostic test to halt mother-to-child transmission
Scientists have assessed a new rapid diagnostic test to identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth.
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Measles elimination versus eradication: The difference explained
As of March 13, the CDC has confirmed 301 cases of measles as well as the death of a child in Texas. Amira Roess, an epidemiologist and professor of global health, clarifies the benefits of vaccinating children and adolescents against measles.
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Tadpoles try to flee dangerous virus in their pond by growing much faster than normal
A new study shows that larvae of wood frogs respond to the presence of a deadly ranavirus by growing and maturing precociously. In response to ranavirus, tadpoles change their growth, development, and resource allocation, which may help them tolerate the energetic demands of infection or escape risky environments to avoid infection.
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Growing body of evidence links HPV with heart disease
In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a study.
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Newer hepatitis B vaccine shows promise as booster for health care workers
A new study compares the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals.
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Evaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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New study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.