All Viruses articles
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Tuberculosis vulnerability of people with HIV: a viral protein implicated
Tuberculosis accounts for one in three deaths among people living with HIV. A new study highlights the key role played by Tat 2 – a viral protein secreted by HIV-infected cells – in this hyper-vulnerability phenomenon.
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Major report tackles Covid’s cardiovascular crisis head-on
Regular Covid vaccinations should continue worldwide to reduce cardiac risks associated with the virus - according to new research.
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Adverse event profiles following HPV vaccination in males
The safety profile among male recipients of human papillomavirus (HPV) vaccination remains a critical evidence gap. A new study presents the first systematic safety evaluation of Gardasil 9 and Gardasil in male recipients.
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HPV integration: Moving from carcinogenesis mechanisms to clinical applications
The clinical significance of HPV integration into the host genome is substantial, particularly in cervical cancer screening programs. Integration testing has emerged as a valuable triage tool for detecting high-grade cervical intraepithelial neoplasia (CIN III+).
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Scientists identify four ways our bodies respond to COVID-19 vaccines
Researchers tracked individuals’ antibody levels after vaccinations and identified four distinct patterns of immune response after the first booster, suggesting that monitoring how antibody levels change over time could assist in identifying individuals at greater risk of infection.
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Disease experts upgrade sentinel chicken system to create forecast for West Nile virus
An interdisciplinary team of experts have created a statistical model that accurately predicts the activity of West Nile virus in an area up to six months in advance. The model was trained using two decades of sentinel chicken data.
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How HIV enters the genome – researchers identify previously unknown mechanism
Researchers have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome. A research team identified RNA:DNA hybrids (R-loops) as molecular signposts for the virus.
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Targeted delivery of microRNA sponge short-hairpin RNA via VIR-inspired biotechnical vector
The Vir-inspired Biotechnical Vector (VIBV) is a novel hybrid platform that combines viral and non-viral elements with nanotechnology to enable personalized, tumor-specific gene therapy.
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AI-powered CRISPR could lead to faster gene therapies, study finds
A new AI tool can help scientists better plan gene-editing experiments. CRISPR-GPT acts as a gene-editing “copilot” supported by AI to help researchers — even those unfamiliar with gene editing — generate designs, analyze data and troubleshoot design flaws.
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U.S. Public Health Service releases new guidelines on occupational HIV exposure and postexposure prophylaxis
The CDC, on behalf of the U.S. Public Health Service (PHS), has released the 2025 Guidelines for the Management of Occupational Exposure to Human Immunodeficiency Virus (HIV) and Recommendations for Postexposure Prophylaxis (PEP).
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Scientists link waning Japanese encephalitis immunity to higher dengue severity
Scientists have found that waning immunity to Japanese encephalitis virus (JEV) may increase the risk of more severe dengue disease in humans. The study highlights how fading vaccine protection from one virus can unintentionally affect the body’s response to another.
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Research identifies immune response that controls Oropouche infection and prevents neurological damage
Research conducted on mice has identified that the rapid response of a specific type of defense cell is essential for controlling Oropouche virus infections and preventing serious neurological damage.
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Researchers find a way to use antibodies to direct T cells to kill Cytomegalovirus-infected cells
Researchers have found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV). They did this by engineering antibodies that direct the immune system’s T-cells to kill cells infected with the virus.
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From Miami to Berlin: stowaway rat delivers valuable pathogen lessons
in 2017, a Miami–Berlin flight took an unexpected turn when passengers spotted a rat on board. The incident underscored how easily pathogens can spread across continents—and why standardized testing of animal stowaways is so important.
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Researchers uncover how COVID-19 may linger in cancer patients and affect treatment outcomes
New research is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. Researchers studied three cancer patients who had undergone transplant therapies and were hospitalized with severe COVID-19 infections.
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Scientists report the first use of CRISPR activation to treat a cardiac disease in mice
Researchers have demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study paves the way for novel targeted therapies for patients with genetic cardiac disorders.
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A ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot
Researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.
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‘Microbial piracy’ uncovers new way to fight drug-resistant infections
Researchers have discovered how ‘pirate phages’ hijack other viruses to break into bacteria, sharing new genetic material for dangerous traits.
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Novel Bocaparvovirus identified in goats in China
Researchers identified a novel Bocaparvovirus in goat fecal samples using metagenomic techniques, with detection in goats from 3 regions in China: Sichuan, Hunan and Chongqing.
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Pediatric investigation study re-examines chikungunya in neglected pediatric victims
Researchers and policymakers must recalibrate their outlook on pediatric chikungunya to develop effective control measures, a new paper warns.