Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
A new review highlights growing scientific evidence that imbalances in gut bacteria can influence metabolism, trigger inflammation, and increase cancer risk. These insights offer new possibilities for disease prevention, early detection, and personalized health care.
Read storyA new review examines how circadian disruption modifies the diversity and metabolic functions of gut microbiota, resulting in alterations of microbial metabolites, including short-chain fatty acids and secondary bile acids.
Using humanized mouse models and blood samples from people living with HIV, resarchers found that reducing overactive plasmacytoid dendritic cells helped restore antiviral T cell function and shrink the viral reservoir.
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.
Five new bacteriophages have recently been discovered in the ponds of Lund University’s Botanical Gardens. Phages thrive wherever bacteria are found, which often means ponds and watercourses that are rich in organic material.
A geospatial study of leptospirosis outbreaks in New South Wales suggests that humans and dogs may have largely independent transmission pathways.
In 2020, Puerto Rico faced a misinformation crisis. Melanie Ortiz Alvarez De La Campa reveals how five STEM undergraduates created a sci-comm organization that helped pass legislation, educated thousands, and created an inclusive database of Caribbean scientists.
The same technology used in COVID-19 vaccines could help prevent muscle damage from snakebites, according to scientists who say it could be even more useful for other conditions where toxins cause harm gradually, such as blocking harmful toxins produced by bacteria during infections.
How can we monitor the cross-species transmission of avian flu? The answer is FluWarning, a digital system that reports abnormal changes in flu viruses. It analyses their genetic code, looking for subtle but significant changes that could indicate cross-species transmission.
A research team has developed a vaccine made from a non-infectious version of the Crimean-Congo hemorrhagic fever virus that protects quickly and provides long-lasting immunity.
Scientists have demonstrated that the marine bacterium Photobacterium angustum exhibits potent antitumor effects against colorectal cancer. The natural bacterium requires no genetic modification yet selectively accumulates in tumor tissues with minimal impact on healthy organs.
Researchers have created the most comprehensive map to date showing how antibodies attach to the SARS-CoV-2 virus, which causes COVID-19, and how viral mutations weaken that attachment.
The Global Virus Network (GVN) is awarding pandemic preparedness research grants, totaling $160,000, to scientists across four continents, supporting innovative, investigator-led projects designed to enhance viral surveillance, early detection, and scientific preparedness.
Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.
Scientists have devised a way to track the evolution and spread of antibiotic resistance in individual bacteria by measuring competition among plasmids. Plasmids evolve independently but also help drive bacterial evolution, including the development of resistance to antimicrobial compounds. They are the primary way that resistance can jump from one type of bacteria to another.
A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study. The findings suggest potential for new treatment strategies.
Recovery from deadly influenza infection may hinge on helping the lungs heal in addition to stopping the virus, according to a new study in mice, which shows that pairing modest antiviral therapies with immune modulation can restore damaged tissues and lung function, even after severe infection has taken hold.
Garlic extract demonstrates antimicrobial efficacy comparable to other widely used antiseptics and disinfectants, such as chlorhexidine, according to scientists. While garlic-based mouthwash may cause more discomfort than chlorhexidine, it offers longer-lasting residual effects.
A new study has found that the levels of antimicrobial resistance (AMR) present in surface water increase during winter. Flooding, sewer overflows and agricultural run-off all contribute to a cocktail of pollutants that can increase AMR genes in surface water, potentially turning regular bugs into ‘superbugs’.
A new paper outlines how scientists came together to put together the first microbial conservation roadmap under the leadership of Applied Microbiology International President, Professor Jack Gilbert.
Researchers have discovered a novel way to fuse lipid vesicles at neutral pH. By harnessing a fragment of the diphtheria toxin, the team achieved vesicle membrane fusion without the need for pre-treatment or harsh conditions, opening the door to new applications.
Scientists have uncovered how even “low-risk” organic fertilizers like dried poultry manure can inadvertently drive a dramatic surge in dangerous antibiotic resistance genes, once released into vegetable plots used for food crops.
A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.