Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
New findings have identified a potential association between COVID-19 and increased lung cancer risk, driven by underlying biological mechanisms in the lung. The study integrates human clinical data with mechanistic research in animal and cellular models.
Read storyScientists have created a platform that allows viral surface proteins to be studied in a form that more closely resembles how they appear naturally, utilizing nanodisc technology where these proteins are embedded into particles made of lipid molecules, preserving them in a membrane-like structure.
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do not offer protection against all forms of TB, finds a large trial from India.
To survive viral attack, bacteria equip themselves with antiviral immune systems. Vibrio cholerae carries a large genetic element called a sedentary chromosomal integron (SCI). A new study investigates whether the SCI might capture gene cassettes from genetic material entering the cell from the outside.
Living with friends may quietly be altering your gut bacteria - according to a new study. Research on a colony of tiny island birds reveals they share more of their gut bacteria with the birds they spend the most time with.
Human papillomavirus (HPV) is a double-stranded circular DNA virus with a genome of approximately 7–8 kb. A new study aims to establish an overlapping extension polymerase chain reaction method for the amplification of the entire genome of HPV16.
Despite decades of research into the gut microbiome, microbiome-based interventions such as probiotics or fecal transplants still produce inconsistent results. Scientists suggest part of the problem may lie not in the microbiome itself, but in how we define what it means to be ‘healthy’.
Scientists have developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.
By simulating the traditional decoction process, researchers successfully isolated structurally intact GGD-PDVLNs from dried Pueraria lobata after boiling. These nanoparticles demonstrated remarkable stability in simulated gastric acid and intestinal fluids.
“Shock-and-kill” strategies aim to reactivate latent virus so infected cells become visible to immune clearance or additional therapies. In a new study, researchers investigated whether exosomes could mediate HIV latency reversal after exposure to Astragalus polysaccharide (APS).
Baroness Natalie Bennett will join leading scientists and policymakers in Belfast for a discussion on how to slow the spread of superbugs at the Microbiology Society’s Annual Conference.
A Phase I clinical trial of a human monoclonal antibody discovered and developed for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data.
A phase III clinical trial will test a gut microbiome intervention as part of a kidney cancer therapy regimen. The investigational agent is a once-daily capsule requiring no refrigeration or special handling.
Chris Armstrong, President of Microbiology, Thermo Fisher Scientific, argues that laboratories should stop judging fungal culture media on unit price alone.
The movement patterns of waterfowl, including ducks, swans and geese, may affect the spread of highly pathogenic avian influenza in bird populations. Researchers found that birds travel much shorter distances in areas with human activity.
Researchers show how tick‑borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates and matures, knowledge that may become important for future treatments against TBE.
Researchers have developed a new solar-powered water disinfection system that combines several existing methods. The compact device effectively utilizes a combination of techniques that all use solar energy.
Mutations in a key protein make a yeast found in dogs with common outer ear infections more resistant to the topical antifungals used to treat it, veterinarians and pathobiologists found in a new study.
An extract of turmeric and ginger helps bone implants bond strongly while killing bacteria and cancer cells, according to new research with implications for millions of patients with joint replacements and bone cancer.
Experiments in mice and human tissue indicate that a reduction in bacteria living in the large intestine decreases mucus production and affects nutrient absorption, particularly in older adults.
Researchers used a computer model to quantify the effect of funding cuts for HIV testing. They estimate that HIV infections could increase an average of 10% in 18 U.S. states if this funding is interrupted or ended.
New research shows that bacteria incorporate polyfluoroalkyl carboxylates—a type of Per- and Polyfluoroalkyl Substances (PFASs)—into the molecules that make up their cell membranes.
Tuberculosis rates for Inuit living in Nunavik, the Inuit lands in northern Quebec, are 1,000 times greater than among non-foreign-born Quebeckers, and underresourcing of local health care adds to hardship from the disease, found new research.