One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
A newly discovered membrane defence help explain antibiotic resistance in Pseudomonas aeruginosa
Scientists have uncovered how Pseudomonas aeruginosa, a major multidrug-resistant superbug, helps block antibiotics from entering its cells. The study identifies two proteins that act like plugs inside a membrane channel, revealing a potential new target for treatments designed to weaken bacterial defenses.
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NewsUniversity of Stirling secures £2.4M grant for major aquaculture project
Antibiotic resistance is becoming an increasing challenge for Vietnam’s vast pangasius catfish industry, where farmers often have few practical alternatives when treatments stop working. A new £2.4 million project will bring scientists, farmers and policymakers together to develop more sustainable ways to control disease and reduce reliance on antibiotics.
NewsWhat makes hantaviruses jump from rodents to humans?
Why do some hantaviruses jump from rodents to humans while others remain largely confined to wildlife? A new study will combine viral genetics, climate data and wildlife ecology to uncover the conditions that drive spillover and help identify where future outbreaks are most likely to emerge.
NewsPooling samples could expand TB testing worldwide
Testing sputum samples in small groups could nearly double access to rapid tuberculosis diagnosis without doubling costs. The largest study of pooled TB testing found that the approach cut molecular test cartridge use by 51%, helping inform new WHO guidance for resource-constrained settings.
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News
A ‘society on a chip’ reveals how viruses spread
Researchers have built a centimetre-scale ‘society on a chip’ that recreates how viruses spread through structured populations. By changing cell density, susceptibility and movement, the platform can mimic transmission, social distancing and even herd-immunity-like effects in real time.
NewsCommon airway bacterium may help prepare lungs to fight pneumonia, study finds
A study found that exposure to Prevotella melaninogenica, a type of bacteria commonly found in healthy airways, changed the behavior of immune cells in the lungs of mice. When the mice were later exposed to Streptococcus pneumoniae, a leading cause of bacterial pneumonia, their immune systems were better able to recognize, engulf and clear the bacteria.
NewsThe benefits of vaccination extend beyond protection from infection
A study, carried out in mice, shows how after recovering from an acute viral infection, animals experienced a long period of impaired immune responsiveness which compromised their immune system’s ability to effectively respond to future challenges. Prior vaccination prevented these detrimental consequences, preserving immune function.
NewsGut microbes across continents trace ancient human migration
A new study has attempted to answer the question of whether homo sapiens hosted a characteristic and diverse microbiome going back millennia. Gaining insight into which, if any, long-term residents of the microbiome co-evolved with humans could point to ways to investigate how the loss of microbial diversity through industrialization impacts human biology.
NewsStudy may explain why IBD patients react to foods they once tolerated
A new study finds that gut inflammation can change the way gut bacteria break down food — possibly triggering immune reactions to foods that were previously fine to eat. The findings may help explain why so many people with inflammatory bowel disease (IBD) react badly to foods like dairy or gluten, even in remission.
NewsDistinct malaria parasites “hidden in plain sight” may contribute to human disease protection
A new study that investigates the genetics of people and malaria parasites has found that people with the sickle cell variant are almost exclusively infected by a distinct variety of malaria parasites, which might contribute to their lower rates of disease.
NewsResearchers publish clinical data for rapid diagnostic urine test to detect invasive aspergillosis
Through long-standing research, which has been supported by the National Institutes of Health, investigators at Johns Hopkins Medicine have advanced insights into ways to better detect invasive aspergillosis (IA). Caused by mold, the infection is uncommon in the general population but can create significant health risks for people with underlying ...
NewsHPV vaccination before pregnancy linked to lower risk of preterm birth and other major complications
Having received the human papillomavirus (HPV) vaccine before pregnancy is associated with a lower risk of major pregnancy complications including preterm birth, with the greater reduction in risk seen among women vaccinated at an earlier age, finds a large Swedish study.
NewsMaternal vaccines protect babies from serious infections, but unequal access limits benefits across Europe
Europe must act now to strengthen maternal vaccination in pregnancy and ensure all women and babies can benefit from a new generation of vaccines to protect against serious infections, says a new series being launched today.
NewsNew study raises questions about antifungal treatments during pregnancy
A study suggests that common antifungal medicines used during pregnancy may be associated with changes in foetal hormone production. However, the researchers cannot yet say whether the differences observed have consequences for the children later in life.
NewsGut bacteria shape how fiber works
Eating more fiber does not necessarily mean the same thing for every gut microbiome. New research shows that plant-based carbohydrates can favor Segatella copri only when certain other bacteria are already present, revealing how strongly diet depends on the microbial community it enters.
NewsResearchers built a low-cost system that knows when coughing is on the rise
What if a room could tell when coughing is on the rise without cameras or identifying anyone? Researchers have developed a low-cost sensor system that uses microphones, AI and lightweight computing to count coughs and distinguish between different coughers, potentially helping hospitals spot increases in respiratory illness earlier.
NewsStudy reveals how a common hospital pathogen senses iron—opening a new avenue for fighting antibiotic resistance
Pseudomonas aeruginosa is a common culprit in hospital-acquired bacterial infections and is growing more resistant to antibiotics. New findings show how a two-protein system inside the bacterium operates like a sensitive switch: the pair detects iron both outside and inside the cell and then rewrites large parts of the microbe’s metabolism in response.
NewsAntimalarial drugs can persist in mosquitoes, exposing malaria parasites, study finds
Antimalarial drugs are designed to protect people from malaria, but they may also affect the mosquitoes exposed to them during blood meals. A new study investigates the impact of these medications on mosquitoes, laying the groundwork for future research into how the drugs may influence the malaria parasites developing within them.
NewsWHO response to report of a death of a laboratory worker in Russia of severe pneumonia
The World Health Orgnanization has issued a statement from WHO Director-General Dr Tedros Adhanom Ghebreyesus on the report of a death of a laboratory worker in Russia of severe pneumonia.
NewsScientists identify gene signatures in children with severe COVID-19 infection
Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other serious respiratory infections. They discovered ten groups of genes which were expressed in a similar pattern across the different lower respiratory tract infections.
NewsPatch brings light to wound care
Researchers working on innovative treatment methods for chronic wounds have developed a material that releases active ingredients in a controlled manner when exposed to light, which could improve the effectiveness of treatment and reduce its side effects.
NewsUganda launches Phase I clinical study of Bundibugyo virus disease vaccine
A Phase I clinical study has been launched evaluating the safety and immunogenicity of a candidate vaccine against Bundibugyo virus disease (BVD), a severe form of Ebola virus disease caused by Bundibugyo virus (BDBV). The study is part of an international effort to develop vaccines against Ebola virus species for which no licensed vaccines are currently available.
NewsKenya confirms first imported Bundibugyo virus disease case; WHO supports control efforts
Following the confirmation by Kenyan authorities of the country’s first imported case of Bundibugyo virus disease (BVD), the World Health Organization (WHO) is working closely with the Government of Kenya to intensify key control measures to prevent further spread of the virus.