One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Researchers uncover hidden toxin risks during nutrient-starved algal blooms
Researchers have shown that extended nutrient deprivation can significantly increase toxin content per cell in the benthic dinoflagellate Prorocentrum lima, even when cell numbers remain relatively stable. Toxin risk may increase quietly under nutrient-poor conditions without obvious bloom expansion.
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NewsNew research finds crosstalk inside cells helps pathogens evade drugs
Biologists have uncovered a new mode of communication inside cells that helps bacterial pathogens learn how to evade drugs. Their findings describe how these mechanisms drive antimicrobial resistance in Listeria monocytogenes, the foodborne bacteria that causes listeriosis.
NewsHow bacteria in the mouth may offer new clues to cognitive dysfunction in people with schizophrenia
An association between oral microbiota and cognitive performance in schizophrenia has been reported by researchers. The study shows that lower oral microbial diversity is associated with poorer cognitive function, with specific predicted microbial metabolic pathways potentially linked to this relationship.
NewsNatural sunscreen compounds show potential to support skin health and blood pressure
Researchers have discovered that natural ‘sunscreen’ compounds found in algae and cyanobacteria may also support skin and heart health.
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News
Gut bacteria may tip the balance between feeding tumors and fueling immunity
A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer.
NewsDissolved bubble microneedles enable more efficient therapy of acne vulgaris
Researchers report a new microneedle-based strategy for acne therapy in a new study. The team developed dissolved bubble microneedle patches that can simultaneously deliver hydrophilic and hydrophobic drugs directly into acne-affected skin.
NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
NewsMetformin shown to prevent Long COVID across risk groups in multiple randomized trials
Multiple randomized clinical trials and electronic health record studies now show that metformin, a widely used and well-established medication, significantly reduces the risk of developing Long COVID when taken during or shortly after acute infection with SARS-CoV-2.
NewsInconsistent standards may be undermining global tracking of antibiotic resistance
A comprehensive review of how antimicrobial resistance is monitored in the environment and why inconsistent interpretation of laboratory results may be distorting our understanding of the scale of the problem.
NewsNipah virus outbreak: Risk of global threat is low, say experts
The Global Virus Network is monitoring reports of a Nipah virus outbreak in India and emphasizes that such cases, while very concerning and serious, are not unexpected or unprecedented.
NewsFrom biocidal coatings to medicines: A nanocomposite sting for microorganisms
A surface capable of responding to chemical signals generated by microorganisms and automatically producing biocidal substances – a description of how the B-STING silica nanocomposite works. The new material acts as a nanofactory of reactive oxygen species, activating only when necessary.
NewsAddressing rapid viral evolution: research team unveils emerging techniques for RNA viruses diagnostics
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex quasispecies populations, present a formidable obstacle to conventional molecular diagnostic approaches, warn researchers.
NewsNasal vaccine combats bird flu infection in rodents
Researchers have developed an intranasal H5N1 vaccine that elicited strong immune responses when tested in hamsters and mice and prevented infections in exposed animals. The team also confirmed their vaccine remained effective regardless of prior flu exposure.
NewsRethinking global AMR strategy: the 2024 WHO Bacterial Priority Pathogens List from a One Health perspective
A new perspective examines the World Health Organization’s 2024 Bacterial Priority Pathogens List (WHO BPPL), highlighting its strengths as a research roadmap while identifying critical gaps for a truly holistic antimicrobial resistance (AMR) strategy.
News£2.8 million research project to combat one of the world’s most urgent health threats
An ambitious new £2.8 million international programme will aim to tackle antimicrobial resistance (AMR) across East Africa. It will examine how environmental, social and economic factors influence the spread of drug-resistant infections in East African communities.
NewsA rapid test using a mobile phone will be able to identify the most severe cases of imported malaria within minutes
A new malaria tool uses a mobile phone to combine rapid diagnostic tests with video analysis and is capable not only of detecting the infection in under six minutes but also of predicting which patients may develop severe forms of malaria.
NewsInstitut Pasteur issues statement on U.S. administration’s attacks against biomedical research, global public health action and vaccination
For several months now, the current U.S. administration has consistently attacked and endeavored to weaken biomedical research and public health action in the United States and worldwide with unparalleled vigor, the Institut Pasteur has said in a new statement.
NewsNew tool shows how to enter and change pneumocystis fungi
Researchers have reported success in genetically modifying the fungal pathogen Pneumocystis murina. Their approach uses extracellular vesicles from mouse lungs to deliver gene-modifying molecules inside the fungal cells. The modified fungus expressed the introduced genomic modifications.
NewsGlowing bacterial sensors detect gut illness in mice before symptoms emerge
Researchers have engineered gut bacteria that dim their fluorescent glow in the presence of illness. Their findings could improve how we diagnose problems in the gut by using bacteria that already live there.
NewsHow genes influence the microbes in our mouths
A new study has found human genetic factors that influence the oral microbiome and may increase risk of cavities and tooth loss in some people. Analysis of the now largest collection of oral microbiome profiles reveals interactions between human and bacterial DNA.
NewsFecal microbiota transplantation improves response to immunotherapy in advanced kidney cancer
A new study provides compelling evidence that fecal microbiota transplantation (FMT) can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma (mRCC).
NewsScientists say these two viruses may become the next public health threats
Two emerging pathogens with animal origins — influenza D virus and canine coronavirus — have so far been quietly flying under the radar, but researchers warn conditions are ripe for the viruses to spread more widely among humans.
NewsIn rare cases, autoantibodies can cause severe reactions to a live-attenuated virus Chikungunya vaccine that has been discontinued in the U.S.
A new study shows that preexisting autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to one kind of Chikungunya vaccine, which is no longer available in the U.S.