One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Hepatitis B is a problem for a growing number of patients on immunosuppressive medications
The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.
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NewsCuriosity-driven experiment helps unravel antibiotic-resistance mystery
An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.
NewsCamel milk udderly good alterative to traditional dairy
In addition to being hypoallergenic, camel milk could potentially protect the gut from harmful enzymes and create healthier digestion. Research has found that camel milk contains more naturally occurring bioactive peptides compared to its bovine counterpart.
NewsAntiviral protein causes genetic changes implicated in Huntington’s disease progression
A new study shows APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, are unusually active in the brains of Huntington’s patients.
More One Health
News
Underestimated risk: Germs in the kitchen
In the most recent BfR consumer monitor, only 17 per cent of respondents said they were concerned about kitchen hygiene. The level of concern about microplastics (68 per cent) and residues of plant protection products in food (52 per cent) is significantly higher.
NewsNew study finds social programs could reduce the spread of HIV by 29%
Researchers have found that addressing barriers to HIV care from depression, homelessness, individual and neighborhood poverty, education disparities, lack of insurance and unemployment could reduce the national HIV incidence by 29% over 10 years.
NewsStructural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
NewsNew research reveals how location influences how our immune system fights disease
Researchers have revealed how cells known as tissue-resident memory CD8 T cells play unique and specialized roles based on where they are located within the small intestine, providing a local first line of defense against re-infection.
NewsScientists discover how the gut modulates the development of inflammatory conditions
Scientists have discovered how gut bacteria that cross a weakened intestinal barrier induce changes in bone marrow that strengthen the immune response.
NewsWhat microbes tell us about Nonalcoholic Fatty Liver Disease
Using medical data from more than 1,200 people, specific microbiome signatures have been identified that allow precise prediction of Nonalcoholic Fatty Liver Disease (NAFLD).
NewsScientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
NewsNew paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
NewsTowards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
NewsScientists synthesize a promising mushroom-derived compound
Researchers have successfully developed the first method to synthesize inaoside A, a compound derived from the edible mushroom Laetiporus cremeiporus.
NewsDihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
NewsBiotin may shield brain from manganese-induced damage, study finds
New research showing the mechanisms by which manganese inflicts damage to the central nervous system suggests that the vitamin biotin - synthesized by gut bacteria - may have a protective effect, potentially mitigating manganese-induced damage.
NewsHuman papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
NewsA Marburg virus outbreak was confirmed in Tanzania
WHO has announced that an outbreak of Marburg virus disease in Tanzania has been confirmed, with 25 suspected cases. Outbreak control measures have been established since the announcement.
NewsScientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
NewsWHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
NewsAncient viral DNA shapes early embryo development
Over half of our genomes consists of remnants of ancient viral DNA which are widespread across the tree of life. Once dismissed as the ’dark side’ of the genome, researchers have now revealed the role of transposable elements in early embryo development.
NewsValneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
NewsResearch team receives $1.5 million to study neurological disorders linked to long COVID
A significant grant was awarded for an upcoming research of cellular and molecular mechanisms in the neurological challenges posed by long COVID-19.
