One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Virgin olive oil protects cognitive health through the gut microbiota
A new study reveals that people who consumed virgin olive oil rather than refined olive oil showed improved cognitive function and greater diversity in their gut microbiota, which is an important marker of intestinal and metabolic health.
Read story
NewsNovel camel antimicrobial peptides show promise against drug-resistant bacteria
Researchers have identified three novel antimicrobial peptides (AMPs) from dromedary camels that effectively target multidrug-resistant bacteria, offering potential alternatives to conventional drugs.
NewsScrub typhus a threat in the home, study in South India finds
Most human scrub typhus infections could occur inside villages rather than during agricultural work, suggests new research conducted with the help of communities living in Tamil Nadu.
NewsElevated E. coli, staph still detected in Potomac river 4 weeks after sewage spill
Nearly a month after a wastewater pipe broke and spewed hundreds of millions of gallons of raw sewage into the Potomac River just north of Washington, D.C., the latest water testing results continue to show high levels of E. coli and S. aureus, including antibiotic-resistant MRSA.
More One Health
News
New single-cell transcriptomic clock reveals intrinsic and systemic T cell aging in COVID-19 and HIV
Scientists developed a new single-cell transcriptomic clock called T immune cell transcriptomic clock (Tictock) to measure aging in specific immune cells. They found that in patients with acute Covid-19, the infection increased the biological age of naïve CD8 T cells.
NewsScientists home in on Acinetobacter baumannii’s resistance evolution
Scientists have found a way to understand how Acinetobacter baumannii is evolving - and how best to strategize a fight against it. They have produced a huge whole-genome look at the rise of this resistance, pointing the way to new strategies in staying ahead of the pathogen.
NewsHoly Grail: One vaccine may provide broad protection against many respiratory infections and allergens
In a new study in mice, researchers have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens.
NewsPersonalized predictions of probiotic and prebiotic therapy success by computer models
A new study demonstrated that computer models of gut metabolism can predict which probiotics will successfully establish themselves in a person’s gut and how different prebiotics affect production of health-promoting short-chain fatty acids.
NewsNew findings on infection with the Epstein-Barr virus
Researchers have identified genetic and non-genetic factors that help the body fight the Epstein-Barr virus. Using a new technique, they were able to estimate the amount of EBV in the blood and find correlations in large health data sets – for example, an increased viral load in people with HIV infections, but also in smokers.
NewsNew insights into how bacteria control DNA synthesis open the door to next generation antimicrobials
A new study combines structural biology, biophysical characterisation and functional assays to delineate how the bacterial transcriptional regulator NrdR’s quaternary structure responds to different nucleotide states and how these changes affect its regulatory activity.
NewsMissed opportunity: Study shows low vaccination rates among expectant mothers in Norway against COVID-19 and influenza
A study of over 50,000 pregnant women in Norway during the 2023/24 influenza season found that only 29.9% were vaccinated against influenza and 12.1% against COVID-19 during pregnancy, remaining far below recommended targets.
NewsNewly discovered virus linked to colorectal cancer
Researchers have discovered a previously undescribed virus in a common gut bacterium, Bacteroides fragilis. The virus appears more frequently in patients with colorectal cancer.
NewsNew review points to faster, safer vaccine development
A new review examines viral mimic systems that reproduce key features of dangerous pathogens such as SARS-CoV-2, the virus that causes Covid-19, without the ability to replicate or cause disease. These systems allow researchers to study infection safely, quickly, and in a wider range of laboratories.
NewsResearchers discover how tuberculosis bacteria use a “stealth” mechanism to evade the immune system
New research reveals that mycobacteria release tiny packages called extracellular vesicles that fuse with the membranes of immune cells. These vesicles contain specialized lipids—fatty molecules—that make the cell membrane more rigid.
NewsPrenatal infection increases risk of heavy drinking later in life
Exposure to infection and other immune stress in the womb increases the likelihood of alcohol misuse in adulthood, a risk that may be reduced through prenatal antioxidant treatment, a new study shows.
NewsScientists discover ‘bacterial constipation’, a new disease caused by gut-drying bacteria
Scientists have found two gut bacteria working together that contribute to chronic constipation. The duo, Akkermansia muciniphila and Bacteroides thetaiotaomicron, destroy the intestinal mucus coating essential for keeping the colon lubricated and feces hydrated.
NewsMissing microbes in UK infant gut and probiotics highlighted by global microbiome atlas
A global atlas mapping two key gut bacteria in infants around the world has uncovered a treasure trove of bacterial strains adapted to the infant gut and not found in commercial probiotic products. It lays the foundation for more effective, tailored infant probiotics.
NewsA ring to transcribe them: The unique path of poxviruses
A study shows for the first time the mechanical elegance with which the viral protein VITF-3 controls the transcription process. Vaccinia viruses, the most widely studied model viruses from the poxvirus family, were examined at the molecular level.
NewsInvasive death cap mushrooms are changing their chemistry
Scientists have just published new research about the chemistry of death cap mushrooms (Amanita phalloides) - the species is not only spreading rapidly as an invasive fungal species in the United States, but the move across continents has changed the chemistry of the species.
NewsNovel vaccine protects against C. diff disease and recurrence
A novel vaccination approach cleared the harmful gut bacterium Clostridioides difficile in an animal model of infection. An experimental vaccine administered to the mucosal lining of the colon protected against illness, death, tissue damage and infection recurrence.
NewsGlobal scientific paper establishes first consensus definition of gut health
A global group of 13 scientists and clinicians is helping establish clarity by publishing a consensus definition of gut health. They define gut health as “a state of normal gastrointestinal function without active gastrointestinal disease and gut-related symptoms that affect quality of life.”
NewsAntimicrobial resistance in foodborne bacteria remains a public health concern in Europe
Antimicrobial resistance (AMR) in common foodborne bacteria such as Salmonella and Campylobacter continues to be a public health concern across Europe, according to a new joint report from EFSA and ECDC.
NewsComplexity key to preventing infection after heart surgery
Research indicates that uniform materials could be the culprit behind deadly infections that can occur when using synthetic materials for cardiovascular grafts.