Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
Exposure to diverse microbes and proteins early in life creates broad immune memory and a specific antibody that helps block allergic reactions later in life. Rather than overreacting to harmless allergens, an experienced immune system responds in a balanced way.
Read storyResearchers have elucidated the parasite exit process - known as egress - after identifying an essential gene, MIC11. To clearly explain egress, the behaviors of Toxoplasma gondii were assessed.
A new review shares recent advances from the field of immune memory and highlights key steps we might take to develop even more effective, longer-lasting immunity against deadly diseases.
The International Association for Dental, Oral, and Craniofacial Research (IADR) has announced Luis Daniel Sansores España, IADR Chilean Division, as the 2026 recipient of the IADR Norton Ross Fellowship.
An increasing number of fungi are becoming resistant to medication, posing serious risks for patients with weakened immune systems. That is why fifty researchers from around the world are calling for action against drug‑resistant fungi.
Cats are not just beloved companions; they are emerging as key “research partners” in unravelling viral cancer mechanisms. A new review explores how feline tumour viruses offer vital insights into human oncology and viral carcinogenesis from a comparative oncology perspective.
Researchers have discovered an unexpectedly high prevalence of Mycobacterium tuberculosis DNA (TB DNA) in patients hospitalized in Boston, suggesting that tuberculosis disease may be significantly underdiagnosed in the United States.
Researchers have published the first detailed structural description of the nucleoprotein-RNA complex in the family Bornaviridae. Their observations revealed the three-dimensional structure of this nucleoprotein-RNA complex, showing ring-like assemblies and viral RNA binds in the inner groove.
New findings reveal that obesity significantly impaired the quality and longevity of antibody responses to a Pseudomonas aeruginosa vaccine in a mouse model. The impaired antibody production was due to defects in germinal centers.
Europe’s dependence on fossil fuels is not only making the continent economically and politically vulnerable, it also has dramatic consequences for the population’s health. Growing air pollution, heat damage and the climate-related spread of infectious diseases are looming, warns a new report.
A multicenter target trial emulation found that for eligible patients hospitalized with community-acquired pneumonia (CAP), health outcomes were similar whether they received a three- to four-day course of antibiotics or a course lasting five days or more.
Extracellular vesicle-associated RNAs can serve as non-invasive biomarkers for early inflammatory bowel disease detection and disease monitoring, and also hold great potential as targets for next-generation targeted therapies, according to a new review.
Epigenetic changes present at birth can impact how an infant’s gut microbiome develops during their first year. Researchers also identified specific epigenetic changes and gut microbes that were associated with signs of autism spectrum disorder (ASD) and ADHD when the children were three years old.
Researchers have developed a natural, biodegradable wash that removed up to 96 per cent of pesticide residue from fruit and slowed browning and moisture loss.
Dr. James Earnest, an assistant professor at the Burnett School of Biomedical Sciences, is leading two new research projects to examine how humans build an immune response to dengue and the Zika virus over time, in pursuit of creating better preventative measures.
Chronic hepatitis B is substantially prevalent across the European Union and European Economic Area (EU/EEA), affecting an estimated 0.7% of the population in the region in 2022, according to a new study.
Fans of Korean skincare may be familiar with ‘hero ingredient’ Madecassic acid for its skin-soothing properties, but researchers have revealed its greater potential for use in the battle against antibiotic resistance.
Long-term HIV remission has been achieved in a patient following a stem cell transplant from a sibling carrying a certain genetic mutation, according to new research.
A study combining forty years of legal and illegal wildlife import-export data with compilations of host–pathogen relationships found that wild mammals that are traded are 1.5 times more likely to share infectious agents with humans than those that are not involved in trade.
New findings have identified a potential association between COVID-19 and increased lung cancer risk, driven by underlying biological mechanisms in the lung. The study integrates human clinical data with mechanistic research in animal and cellular models.
Scientists have created a platform that allows viral surface proteins to be studied in a form that more closely resembles how they appear naturally, utilizing nanodisc technology where these proteins are embedded into particles made of lipid molecules, preserving them in a membrane-like structure.
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do not offer protection against all forms of TB, finds a large trial from India.
To survive viral attack, bacteria equip themselves with antiviral immune systems. Vibrio cholerae carries a large genetic element called a sedentary chromosomal integron (SCI). A new study investigates whether the SCI might capture gene cassettes from genetic material entering the cell from the outside.