One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Immune system overreaction linked to deadly flu in pregnancy
Researchers have discovered why influenza can lead to life-threatening complications during pregnancy. In most people, influenza stays in the upper respiratory tract and clears without spreading further. But during pregnancy, the virus can extend into the cardiovascular system, increasing the risk of severe complications for mothers and babies.
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NewsResearchers link human molecular, microbial diversity with geography, ethnicity
Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup — from metabolism and immunity to gut microbiota and biological aging.
NewsReview highlights antimicrobial peptides as cross-seeding modulators at the neurodegenerative–infectious interface
In a comprehensive review, researchers synthesize emerging evidence that antimicrobial peptides and disease-related amyloids can influence one another through heterotypic cross-seeding interactions.
NewsAI and supercomputer simulations reveal how a bacterial energy-converting enzyme pumps sodium ions
The Na+-NQR enzyme is vital for energy production in pathogenic bacteria, making it a highly promising target for new antibiotics. Researchers combined modified artificial intelligence techniques with extensive supercomputer simulations to visualize the hidden, dynamic movements of this enzyme during sodium transport.
More One Health
News
Understanding and exploiting tuberculosis superspreading
A new perspective piece introduces the idea of “superspreading niches”, specific parts of community contact networks where highly infectious individuals intersect with highly susceptible contacts, as a key framework for understanding TB superspreading and designing new TB control interventions.
NewsStudy is first to detect and track multiple cancer-causing viruses in wastewater
A study is the first comprehensive approach to detect all known cancer-causing or oncogenic viruses concurrently by analyzing viral genomes in wastewater. The work shows that it is feasible to monitor the presence and levels of cancer-causing viruses, enabling the possibility of public health interventions in the future.
NewsImplantable living materials autonomously deliver therapeutics using contained engineered bacteria
Researchers have introduced an implantable “living material” that contains bacteria that sense infections. It can release these therapeutic molecules on demand, while keeping them physically separated from the surrounding tissue.
NewsNew report charts path for climate-disease preparedness
Changing patterns of temperature and precipitation, along with sea level rise and more extreme weather events, are impacting the ecology, evolution, distribution and prevalence of infectious disease reservoirs, hosts, vectors and pathogens. As a result, new diseases are emerging, and others are reappearing in regions where they were once uncommon.
NewsWhy babies are dying and how we can stop it
A study has identified that the vast majority of neonatal deaths caused by infections in South Africa and other low-and-middle-income countries could be prevented through improved clinical care and targeted medical interventions.
NewsBacteria may hold a cancer treatment clue
A review argues that tumors with reproducibly poor prognosis outcomes may share an overlooked feature: bacterial infection within the tumor microenvironment. These bacteria may weaken treatment by altering local immunity, damaging tissue structure, and even inactivating chemotherapeutic drugs.
NewsInfluenza virus platforms: New hope for vaccines and cancer immunotherapy
Influenza virus is now being engineered to carry foreign genes and reduce virulence, serving not only for next-generation influenza vaccines but also as delivery vectors for heterologous antigens against other infections and cancers, supported by its ability to trigger robust mucosal and systemic immune responses.
NewsIgG fucosylation linked to severe COVID-19 progression and traditional Chinese medicine therapy
A new study has uncovered that immunoglobulin G (IgG) fucosylation, a critical type of protein glycosylation, is closely associated with the progression of severe COVID-19, offering new insights into disease pathogenesis and potential therapeutic strategies.
NewsTraditional dengue alerts are missing the mark as Vietnam’s climate shifts—researchers propose a one health solution
For decades, Vietnam’s dengue surveillance relied on a straightforward logic: when cases exceed the five-year average by a sufficient margin, sound the alarm. That logic is now breaking down.
NewsProbiotic Lactobacillus rhamnosus CMU-pb-7 shows promise in alleviating diabetic nephropathy via antioxidative pathway
Rats with diabetic nephropathy treated with the probiotic strain Lactobacillus rhamnosus CMU-pb-7 showed marked improvements in general condition and serum biochemical profiles, including significant reductions in cholesterol, triglycerides, blood urea nitrogen, and serum creatinine.
NewsStudy quantifies the staggering economic toll of TB
Researchers have found that TB wipes out an estimated 0.8 per cent of the world’s total economic potential every year. Losses are concentrated overwhelmingly in low- and middle-income countries, especially in South Asia and sub-Saharan Africa.
NewsPublic housing mold intervention program reduces asthma-related ED visits
The New York City Housing Authority developed a mold-removal program in response to a 2013 class-action lawsuit filed by residents suffering from asthma due to mold in their apartments. Without Mold Busters, residents would have experienced 25 per cent more asthma-related emergency department (ED) visits.
NewsResearchers find increased bacteria infection in patients with chronic lung disease
A new study has found that people with bronchiectasis and chronic sinus disease were more likely to have mucus samples that tested positive for Pseudomonas aeruginosa. It suggests that doctors caring for patients with bronchiectasis may need to pay closer attention to sinus disease and bacterial testing.
NewsDiseases can spread between apartments via shared ventilation, study shows
Airborne diseases like measles, influenza and COVID-19 can easily spread between units in multi-family buildings via a type of bathroom ventilation system commonly used around the world, new research suggests.
NewsFriendly skin bacteria offer hope to beat eczema
Friendly skin bacteria could hold the key to stopping eczema in its tracks, according to researchers. A new study reveals harmless microbes living on our skin release powerful molecules that can shut down the inflammatory chaos triggered by Staphylococcus aureus, the bug long known to wreak havoc in eczema.
NewsExperts call on WHO to revisit its approach to airborne risk in light of hantavirus outbreak
In light of the hantavirus outbreak, public health experts have called on the World Health Organization (WHO) to shift its default response to emerging respiratory viruses. The starting point should not be to downplay the risk of airborne transmission until it is definitively proven, they warned.
NewsFlawed but correctable research hindered progress in infection-triggered chronic conditions
Researchers contend that studies of infection-associated chronic illnesses such as Lyme disease and COVID-19 suffer recurring problems such as the failure to prove participants have the relevant pathogen.
NewsWine’s leftovers could help wean chicken farms off antibiotics
Every year, millions of gallons of wine are pressed, leaving behind a mountain of pulpy residue that wineries struggle to dispose of. Now, researchers say this overlooked byproduct could serve as a replacement for the antibiotics routinely added to chicken feed.