One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Scientists develop breakthrough culture system to unlock secrets of skin microbiome
The co-culture system for skin microbiome can help understand interactions between bacterial species, aiding the development of specialized skin treatments.
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NewsHow protective antibodies get in malaria’s way
Researcher’s structural insights help reveal weak spot in parasite’s plan of attack which could help guide vaccine design.
NewsGut feelings: Social connections change our microbiomes
Friends tend to share common interests, tastes, lifestyles, and other traits, but a new Yale-led study demonstrates that similarities among buddies can also include the makeup of the microbes lining their guts.
NewsStudy uncovers key heart responses to viral infection
Researchers at the University of Virginia have made a significant discovery that could change how doctors treat viral infections of the heart.
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News
Probiotic delivers anticancer drug to the gut
Researchers have engineered a probiotic that delivers immunotherapy directly to the gut to shrink tumors in mice, offering a potentially promising oral drug for hard-to-reach cancers.
NewsHuman antibodies could prevent the malaria parasite from causing life-threatening infections
Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five. In a new study, published in the journal Nature, researchers from EMBL Barcelona, the University of Texas, the ...
NewsEnzyme produced by pathogenic fungus helps evade immune system and facilitates infection
Researchers found 62 proteins specific to spores of Aspergillus fumigatus, a fungal species that causes lung disease. The study showed that at least one of these proteins inhibits human human defense mechanisms.
NewsCigarette smoke alters microbiota and aggravates flu severity
New research has shown that cigarette smoke can induce disordered oropharyngeal microbiota that aggravates the severity of influenza A virus infection.
NewsInnovative antibiotic shows promise for drug-resistant bacteria
Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, reporting proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.
Careers‘It’s been an eye-opener’: Thomas Thompson on his year as a Junior Editor
One year into our first Junior Editor training programme with Letters in Applied Microbiology, Dr Thomas Thompson of Queen’s University Belfast tells us how he is getting on.
NewsWomen’s health company Freya Biosciences announces key $10.4m strategic investment
Freya Biosciences, a transatlantic biotech company specializing in women’s health, has announced a major strategic investment which will be used to develop microbial immunotherapies for the treatment of bacterial vaginosis.
NewsResearchers use biophysics to design new vaccines against RSV and related respiratory viruses
Scientists improved existing vaccines by analyzing the molecular structure and stability of viral proteins.
NewsResearchers reveal HIV latency reversing properties in African plant
Scientists have uncovered mechanisms of a medicinal plant with anti-HIV potential. Croton oligandrus Pierre & Hutch is a species of tree used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes.
NewsDoes microbiome contribute to longevity?
Researchers compared the gut microbiota of Chinese individuals in two different age groups, long-living adults (aged over 90 years) and elderly adults (aged 65–74 years) who were free of major diseases.
NewsNew clinical study confirms the anti-obesity effects of kimchi
A clinical trial on the body fat-reducing effects of kimchi indicates that a steady consumption of kimchi is effective in alleviating obesity symptoms through the modulation of the gut microbiota.
NewsMeningitis has a much greater impact on child mortality than previously thought
New study reveals high rates of antibiotic-resistant bacteria in hospital-associated cases of meningitis in children under five years of age.
NewsNew research could pave way for vaccine against deadly wildlife disease
A researcher has been awarded a $2.4 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study the cause of Bang’s disease, Brucella abortus.
NewsTherapeutic proven to reduce advanced-stage influenza viral loads faster, more thoroughly in preclinical studies
Eradivir, a preclinical biotech company, has developed a patent-pending antiviral therapeutic that reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively than currently available therapies.
NewsOral microbiome varies with life stress and mental health symptoms in pregnant women
The number and type of microbes present in the saliva of pregnant women differ according to whether they are experiencing life stress and symptoms of anxiety, depression and post-traumatic stress disorder (PTSD), finds a study published in the open access journal BMJ Mental Health.
NewsPHIOGEN announces collaboration with Live UTI Free to drive patient-focused clinical trials
A biotech company developing live biotherapeutic products for drug-resistant and recurrent bacterial infections, is collaborating with a patient research and advocacy organization to empower their clinical development efforts.
NewsSeemingly ‘broken’ genes in coronaviruses may be essential for viral survival
Some coronaviruses, including Covid-19 have extra ‘accessory’ genes in addition to the usual minimal viral set and researchers have found that some of these viral genes have stuck around even though they don’t produce a working protein.
NewsHepatitis E virus attacks nerve cells
A research study using a cell model has enabled research into how hepatitis E virus affects nerve cells for the first time.
NewsScientists recreate mouse from gene older than animal life
New research sheds light on evolutionary origins of stem cells with groundbreaking experiment to create mouse using ancient genetic tools.
