One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Many TB cases may have gone undetected in prisons in Europe and the Americas during COVID-19
A new study found that reported diagnoses for tuberculosis were consistently lower than expected throughout the pandemic, even though incarceration rates remained largely consistent.
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NewsMpox could become a serious global threat, scientists warn
Mpox has the potential to become a significant global health threat if taken too lightly. Scientists highlight how mpox – traditionally spread from animals to humans – is now showing clear signs of sustained human-to-human transmission.
NewsDeadly antibiotic-resistant ‘superbug’ bacteria spreading in Malaysian hospital
A virulent strain of antibiotic-resistant ‘superbug’ that causes severe disease has been found circulating in a Malaysian hospital - posing significant challenges to global public health, a new study reveals.
NewsMOPEVACLAS vaccine candidate for Lassa fever enters clinical trials
After more than 20 years of research on arenaviruses, researchers have developed an original vaccine platform known as MOPEVAC. A Phase Ia clinical trial is set to begin for the platform’s first vaccine candidate, which targets Lassa fever, a hemorrhagic fever responsible for thousands of deaths worldwide each year.
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News
Researchers develop machine learning model to predict virus reservoirs
A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans.
NewsScientists tackle the rising global challenge of Chagas Disease
A study sheds new light on how the Chagas Disease parasite invades human cells—a crucial step towards developing effective treatments for this neglected tropical disease.
Careers Revolutionizing water safety: a rapid solution for detecting Shiga toxin-producing Escherichia coli contamination
Contaminated water is particularly dangerous in rural areas where private groundwater wells supply drinking water to households - but AMI One Health Advisory Group member Dr Zina Alfahl reveals a low-cost, simple way to check for STEC.
NewsResearchers develop new DNA test for personalized treatment of bacterial vaginosis
Researchers have developed a simple DNA PCR-based lab test — built on a more detailed genetic analysis of the main group of bacterial organisms that cause bacterial vaginosis — to help clinicians prescribe the right medicine for each patient.
NewsYellow pigment from Streptomyces coelicolor offers potential weapon against breast cancer
A new study aims to explore the effect of a yellow pigment (OR3), from a new isolate of Streptomyces coelicolor JUACT03 on metastatic breast cancer.
NewsPartnering diet and intestinal microbes to protect against GI disease
New research suggests that we could get more out of our diets by harnessing intestinal microbes to break down plant compounds collectively known as phenolic glycosides. These compounds pair sugar molecules with a host of small molecules beneficial to human health.
NewsCompelling data point to a single, unknown respiratory virus as cause of Kawasaki disease
New research strongly suggests that Kawasaki disease is caused by a single respiratory virus that is yet to be identified. Findings contradict the theory that many different pathogens or toxins could cause this disease that can lead to serious cardiac complications in young children.
NewsOnly few disinfectants are capable of inactivating hepatitis A virus
Researchers tested nine different surface disinfectants against Hepatitis A virus. According to their findings, only two aldehyde-based products proved effective at inactivating HAV.
NewsNew approach could treat anthrax beyond the ‘point of no return’
Once a case of anthrax has progressed beyond the “point of no return” after just a few days, patients are almost certainly doomed. But a new study shows that a cocktail of growth factors reverses would-be lethal cell damage in mice with anthrax.
NewsmRNA-based COVID-19 vaccines train the ‘long-term memory’ of the innate immune system
A study showed that vaccination of multiple mRNA-based COVID-19 vaccines could induce persistent epigenetic changes in innate immune cells, leading to long-term immune responses for SARS-CoV-2 and other pathogens.
NewsResearchers design genetic tools to develop vaccines more efficiently for African swine fever virus (ASFV)
A synthetic genomic-based reverse genetics tool has been developed for African swine fever virus (ASFV) that helps vaccine development to reduce the economic losses. The system may also be adapted to other emerging viral threats.
NewsProbiotic may improve sleep quality: new research findings
A recent study has identified a potential new approach to managing sleep disorders. The research focuses on the role of S-adenosylmethionine (SAM)-producing probiotics in regulating sleep and circadian rhythms.
News‘It’s a shot, not a vaccine like MMR’: New skepticism prompts call for action
This ‘vaccine is not a vaccine’ is a new, previously unreported type of vaccine-specific scepticism, and it arose only during the COVID-19 pandemic. However, it might, according to the researchers, also apply to the flu vaccine.
NewsScientists zoom in on structure of still lethal Ebola virus
The first high-resolution visualisation of the Ebola virus nucleocapsid provides detailed insights into the interactions within the nucleocapsid complex, unveiling the relationship between molecular interactions and functional regulation.
NewsSecurity-relevant research in times of geopolitical polarisation: report
A new report on security-relevant research - including research into pathogens - notes a change within the scientific system due to increased national security interests.
NewsBfR organises three-day conference on food microbiology
The German Federal Institute for Risk Assessment, the German Society for Microbiology and Hygiene (DGHM) and the Association for General and Applied Microbiology (VAAM) are inviting researchers to the 19th Food Microbiology Conference in Berlin from 1 to 3 April.
NewsStudy reveals how dextran sulfate sodium-induced colitis exacerbates periodontitis
A new study provides strong evidence that the NOX2/ROS axis plays a key role in the exacerbation of periodontitis in the presence of colitis.
NewsSea buckthorn extract exerts anti-free radical, antibacterial and whitening effects on skin
Sea buckthorn flavonoids exhibited excellent antimicrobial, anti-inflammatory and whitening effects in a new study. The inhibitory effect of sea buckthorn flavonoids on Propionibacterium acnes were assessed by plate antibacterial assays.
NewsProposed cuts to foreign aid could result in millions of HIV deaths, new modelling study estimates
New modelling analysis suggests that proposed funding cuts by major donor countries to foreign aid could undo decades of progress made to end HIV/AIDS as a public health threat and new infections and deaths could surge back to levels not seen since the early 2000s.