All USA & Canada articles
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Scientists map essential genome of malaria parasite Plasmodium knowlesi
Comprehensive genetic mapping of Plasmodium knowlesi, a zoonotic parasite that causes malaria, has revealed the genes required for malaria infection of the blood, and those driving drug resistance.
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Impact of rapid urbanization on the emergence of zoonotic diseases
A study has looked into the rapid urbanization into the wildland-urban interface (WUI) causing the spillover of zoonotic diseases, which would help mapping for disease transmission risks.
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Jumbo phages deploying secret handshakes could usher in new antibiotics
Jumbo phages create a restricted space inside bacteria where they can copy their DNA while surrounded by a protective shield. A new study reveals that the shield works via a set of ’secret handshakes’, allowing only a specific set of useful proteins to pass through.
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Researchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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Nasal COVID-19 vaccine to enter US clinical trials
A nasal vaccine for COVID-19 is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA).
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New study reveals how Sudan virus binds to human cells
The interaction between human NPC1 receptor and Sudan virus, closely related to Ebola virus, has been structurally characterised, and gives insight to the pathogenesis of other related filoviruses.
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NIH awards $20.6 million grant to establish Human Virome Characterization Center at UCLA
NIH has awarded a $20.6 million grant over five years to establish one of five Human Virome Characterization Centers to advance understanding of the virome’s role in human health and disease across the oral-gut-brain axis.
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How worried should we be about bird flu? An expert explains.
As U.S. health officials announce that a new strain of avian flu, H5N9, has been discovered on a duck farm in California, UC Berkeley School of Public Health’s John Swartzberg opens up on how much of a threat it poses.
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Yellowstone yields insights into how ancient microbes adapted to Great Oxidation Event
A new study highlights fresh knowledge of how ancient microorganisms adapted from a low-oxygen prehistoric environment to the one that exists today. It compared heat-loving organisms in two thermal features within Yellowstone National Park.
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Africa’s largest human microbiome study sheds light on gut diversity and health
The most extensive study of the gut microbiome in Africa has discovered new microbial species and never-before-reported metagenomes from several African sites.
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Scientists probe honeybee antiviral defense mechanisms
Scientists are investigating honeybee antiviral defense mechanisms with the goal of developing strategies to reduce honeybee colony deaths.
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NIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
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Gene found in rough Salmonella Infantis variant offers drug target for variety of pathogens
A new study identifies a gene in a rough Salmonella Infantis variant that could offer a target for developing effective vaccines and therapeutic strategies, not only for Salmonella but other Enterobacteriaceae as well.
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Why you shouldn’t scratch an itchy rash: New study explains
New research uncovers how scratching aggravates inflammation and swelling in a mouse model of a type of eczema called allergic contact dermatitis.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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New tool can detect fast-spreading SARS-COV-2 variants before they take off
By analysing millions of viral genome sequences from around the world, a team of scientists has uncovered the specific mutations that give SARS-CoV-2 a ‘turbo boost’ in its ability to spread.
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Fungal protein yields new ways to modulate cell activity remotely
A new study introduces tools that remotely and non-invasively communicate with and control the activity of engineered cells once they’ve entered the body. It focuses on a fungal protein the team have developed called Melt, which can be toggled by temperature.
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Papers outline 4 advances for inactivating infectious viruses and bacteria
Four papers provide insights into novel antiviral compounds and methods to inactivate infectious viral particles and bacteria.
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Study finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
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Researchers identify genetic ‘fingerprint’ to predict drug resistance in bacteria
To avoid antibiotic overuse and allow precise bacterial infection treatment, particularly against bacteria with multidrug resistance, a diagnostic tool was developed that identifies the pattern of DNA repair deficiencies acting as the bacterial antibiotic resistance ‘fingerprint’.