All Zika Virus articles – Page 2
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News
Prior zika infection increases risk of subsequent severe dengue and hospitalization
A study suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
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Cases of chikungunya and zika fall in Brazil, but most risk clusters rise
Researchers observed spatial and temporal patterns of occurrence and co-occurrence for the two arboviral diseases in all Brazilian municipalities, alongside the influence of environmental and socio-economic factors.
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Zika virus is effective when used to treat a type of childhood cancer in mice
Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a new study.
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Industry collaboration funds development of RNA drugs against dengue fever virus
University team use patented nuclear magnetic resonance (NMR)-based screening method to identify small molecules that specifically bind to the viruses’ highly conserved RNA structures and interrupt the viral infection cycle.
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Study reveals Zika’s shape-shifting machinery—and a possible vulnerability
Zika’s crucial enzyme performs multiple tasks, but a wrench in the system could bring it to a screeching halt.
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Scientists develop needle-free patch vaccine to protect against Zika virus
A simple-to-apply, needle-free vaccine patch has been developed to protect people from the potentially deadly mosquito-borne Zika virus.
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Maternal dengue immunity worsens birth defects caused by Zika virus
A new study finds prior dengue antibodies substantially raise the risk of microcephaly and fetal defects with Zika infection.
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Zika infection in pregnant macaques slows fetal growth
Zika virus infection in pregnant rhesus macaques slows fetal growth and affects how infants and mothers interact in the first month of life, according to a new study.
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Reduced activity of key enzyme linked to microcephaly in Zika-infected offspring
Researchers have shown that brain activity of Ndel1, an enzyme that plays an important role in neuron differentiation and migration, decreased in mice infected by Zika during pregnancy.
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Nobel Prize goes to researchers whose discoveries paved way for mRNA vaccines
The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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Researchers combat Zika-associated foetal abnormalities using microRNA
Researchers have studied how the Zika virus persists in the placenta for long periods of time and how to mitigate it.
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Discovery in mosquitoes could lead to new strategy against dengue fever
Researchers have discovered that a protein in the mosquito Aedes aegypti , Argonaute 2, has a key role - via several biological mechanisms - in keeping mosquitoes healthy and active despite the presence of viral infections like dengue and Zika.
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Novel molecules fight viruses by bursting their bubble-like membranes
Researchers show how a group of novel molecules inspired by our own immune system inactivates several viruses, including Zika and chikungunya, by targeting the viral membranes, rather than the proteins.
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Picolinic acid reveals its broad-spectrum antiviral abilities
Picolinic acid, a natural compound produced by mammalian cells, can block several disease-causing viruses such as SARS-CoV-2 and influenza A viruses, according to a new study.
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Features
A new frontier in Zika vaccine development
A milestone achievement for science in combating the Zika virus as a new vaccine trial begins in the UK.
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Liverpool begins first human trial of Zika vaccine
The first participant has received a dose of a new Zika virus vaccine being trialled by the University of Liverpool.
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Obese pregnant women infected by zika virus have impaired immune response
Researchers have shown for the first time that gestational obesity associated with infection by zika virus influences the placenta’s antiviral response, weakening the organ’s capacity to attack the pathogen and protect the foetus.
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Zika virus may combat prostate cancer - but study highlights possible side-effect
When researchers analyzed zika’s effects on normal and cancer cells, they discovered that while the virus can be used to treat the disease, it may trigger a harmful inflammatory process and damage the male reproductive system.
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CRISPR self-destruct protein may yield new tests for many viruses
A recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA and holding potential for the development of at-home diagnostic tests for a wide range of infectious diseases.
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Researchers infect ‘brain in a dish’ in pursuit of Zika antivirals
A University of Queensland-led project has used a ‘brain in a dish’ to study the effects of the Zika virus, taking research a step closer towards developing drugs to combat the infection.
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