All Whole genome sequencing articles
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NewsGenome researchers unfurl protective mantle of influenza virus
The structure of the flu virus’s protective mantle and its interactions with its RNA have been described on an atomic scale by a research team for the first time.
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NewsStudy assesses virulence of Cryptococcus strains, laying groundwork for improved treatment
A research group has just completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus, taking us a step closer towards improved treatment of the fungal pathogen.
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OpinionSharing microbial sequence-based data: The way forward
Public sector data associated with health are a highly valuable resource, yet in practice data-sharing poses multiple challenges. Dr Nicola Holden, from AMI’s One Health Scientific Advisory Group, explores the murky morass of big data.
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FeaturesDiscovering the microbial world on Galapagos giant tortoise shells
The Galapagos giant tortoises are not only a marvel of nature but also a symbol of conservation efforts, inspiring scientists around the globe to protect endangered species. They are living relics of a time when these slow-moving giants roamed the continents.
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NewsProvidencia rustigianii has virulence gene akin to Salmonella’s
Food poisoning microbe Providencia rustigianii, isolated from pediatric gastroenteritis patients, has undergone whole genome sequencing, revealing that it possesses a virulence factor called the type III secretion system.
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NewsScientists map DNA of Lyme disease bacteria
Scientists have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.
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NewsMegamonas bacterium found to influence obesity risk
A recent study identifies a potential obesity-linked bacterium, Megamonas, from a large-scale cohort of obese individuals in China, illustrating how the bacterium degrades intestinal myo-inositol, enhances lipid absorption, and contributes to obesity.
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NewsScientists sequence rabies genome in black bear
Researchers have published their findings after they sequenced the entire genome of the virus and compared it with existing rabies sequences from other animals.
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NewsExperts call for global genetic warning system to combat the next pandemic and antimicrobial resistance
Clinical and public health microbiologists have called for investment in technology, capacity, expertise, and collaboration to put genomic surveillance of pathogens at the forefront of future pandemic preparedness.
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NewsSmall is beautiful when it comes to genomics analysis
Choice of alignment algorithms can make a huge difference to the outcome when you’re examining SARS-CoV-2 genome sequences, researchers will tell the Letters in Applied Microbiology ECS Research Symposium.
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NewsResearchers support increased genomic sequencing of dengue for more effective prevention
Molecular epidemiologic data from whole-genome sequencing of dengue serotypes could enhance dengue outbreak preparedness, researchers say.
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NewsOne death and 30 illness cases due to STEC 0145 outbreak in UK
One person has died in the UK and 30 cases of illness confirmed following an outbreak of Shiga toxin-producing Escherichia coli (STEC) O145 identified through the analysis of whole genome sequencing (WGS) data.
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NewsDrug-resistant tuberculosis may be under-diagnosed, reveals genomic analysis
This genomic sequencing study, in southern Mozambique, is the first to characterise the drug resistance profile at the population level and identify mutations that escape routine diagnostic tests.
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NewsAMI teams up with QIAGEN to offer free guide for improving soil DNA extraction
Applied Microbiology International has teamed up with international supplier of scientific equipment QIAGEN, to offer our readers free access to their latest recommendations for soil DNA extraction from sample to insight.
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NewsBat immune genes protect against COVID and cancer
Bats have acquired remarkable traits throughout their evolution. They’re the only mammals that can fly, and they live much longer than other animals their size. But perhaps most impressive is their robust immune system. It protects bats from viruses that wreak havoc in humans, like COVID-19 or Ebola, and also ...
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NewsAntiviral drug linked to SARS-CoV-2 mutations
Researchers have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.
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NewsKey gene for resistance to HIV replication found in people of African ancestry
Scientists have identified a novel region in the genome that is only variable in populations of African ancestries and provided evidence that the gene CHD1L acts to limit HIV replication in a subset of white blood cells.
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NewsNew cholera substrains in Bangladesh uncovered by genomic surveillance
Researchers have uncovered two new cholera substrains in a displaced refugee population in southern Bangladesh, where a pre-emptive mass vaccination campaign of over one million refugees was successful in preventing an epidemic.
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NewsVaginal suppository with lactobacilli can prevent recurrent cystitis
Scientists find that administration of Lactobacilli could mitigate the differences in vaginal microbiota between women with and without recurrent cystitis.
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NewsMapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
