All Weill Cornell Medicine articles
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Immune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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Novel molecular maneuver helps malaria parasite dodge the immune system
Researchers have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system. Plasmodium falciparum can shut down a key set of genes, rendering itself “immunologically invisible.”
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New CDC nPEP Guidelines should become ‘part of general medical practice’
Health experts say the updated CDC HIV Non-Occupational Post Exposure Prophylaxis (nPEP) Guidelines should be part of general medical practice, as incorporating them will reduce new HIV infections and improve public health.
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Dr. Sabine Ehrt named Chair of the Department of Microbiology and Immunology at Weill Cornell Medicine
Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine.
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Gut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
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Microbes in Brooklyn Superfund site teach lessons on fighting industrial pollution
Researchers discover unprecedented pollution-fighting genetic adaptations in tiny organisms inhabiting Brooklyn’s highly contaminated Gowanus Canal, revealing a potential new approach for cleaning contaminated waters and recovering valuable resources.
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Parasitic infection and treatment linked to cancer-related gene activity in the cervix
New research has revealed that Schistosoma haematobium, a parasitic infection affecting millions globally, can trigger cancer-related gene activity in the cervical lining, with changes becoming even more pronounced after treatment.
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Study finds new targets needed for vaccine to prevent herpesvirus transmission to babies
Despite the lack of research on vaccines against congenital cytomegalovirus (CMV), a research has recently discovered that the virus is able to cause cross-placental transmission even with the absence of multple essential proteins, providing insights for future vaccine development.
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens the door to new treatments.
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Study uncovers new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study.
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Study untangles how COVID-19 wreaks widespread damage in the body
A new study sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.
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Mouse gut fungus reveals secrets of symbiosis and allergy
A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research. The finding suggests that preclinical studies until now have overlooked a major influencer of mouse physiology.
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$5.6 million grant awarded to target treatments for IBS, Crohn’s and Ulcerative colitis
An “out-of-the-box” study has been awarded a $5.6 million NIH grant to target treatments for IBS, Crohn’s, Ulcerative Colitis and more.
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Could a bout of COVID protect you from a severe case of flu?
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one?
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Antiviral-resistant variants of SARS-CoV-2 can emerge in immunocompromised people
Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population.
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NIH funds consortium to accelerate development of new TB treatments
A new consortium has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis.
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Study backs RSV vaccine safety during pregnancy
Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a new study.
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New lab test to detect persistent HIV strains in Africa may aid search for cure
A multinational team has developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.