All Viruses articles – Page 9
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).
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Uprooting Cassava Disease: scientists identify causes of two devastating diseases
In a series of studies, researchers have established the pathogens and the first diagnostic tests for two diseases: Cassava Frogskin Disease and Cassava Witches’ Broom Disease.
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Child undernutrition may be contributing to global measles outbreaks
A study of fully vaccinated children finds a link between stunted growth and weakened immunity, suggesting combatting child hunger could help prevent the disease’s spread.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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The hunt narrows for Ebola virus hosts
A cholesterol-trafficking receptor, Niemann-Pick C1 (NPC1), was identified for more efficient surveillance of host reservoirs of filoviruses, including Ebolaviruses. It narrows down the host species of the virus and links to the geographic information of pathogen emergence.
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Scientists develop new 'twindemic' diagnostic system for rapid viral testing
A team of scientists has recently developed a novel TwinDemic Detection (TDD) system, designed for simultaneous detection of SARS-CoV and influenza A virus (IAV).
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Bird flu is mutating - but antivirals still work
Researchers have identified nine mutations in a bird flu strain from a person in Texas. The bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.
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Scientists lift lid on global threat of Nipah virus
A new review underscores the need for a multidisciplinary approach to address the NiV threat, including development of effective therapeutics and vaccines, and implementation of robust infection control measures to prevent outbreaks and protect public health.
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‘Perfect storm’ of mutations drives infection-triggered autoimmune disease
Scientists have discovered how a hepatitis C infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to developing treatments for autoimmune conditions.
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Hepatitis E vaccination is effective in an epidemic
A case-control study has proved the effectiveness of the two-doses Hecolin vaccine against a potential hepatitis E outbreak.
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Genetic mutation linked to higher SARS-CoV-2 risk
Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus’ ability to invade human cells.
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Research aims for better control of widespread tomato spotted wilt virus
Texas A&M AgriLife Research scientists have received two grants to develop better control and understanding of tomato spotted wilt virus, one of the top 10 most economically important plant viruses in the world.
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Study finds cases of ME/CFS increase following SARS-CoV-2
New findings suggest that infection with SARS-CoV-2, the virus that causes COVID-19, may be associated with an increase in the number of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) cases.
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Promising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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Route of entry for Semliki Forest virus into the brain revealed, yielding brain cancer treatment hope
Researchers have shown that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and binding to a specific cell type before penetrating deeper into the brain, potentially tagging the virus as an agent for treating brain cancer.
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New insights offer hope for developing antiviral therapeutics targeting mpox
New research provides novel perspectives on the biological function of G4s in the lifecycle of MPXV and offer potential avenues for developing antiviral therapeutics targeting mpox prevention and treatment.
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Wrong place, wrong time: Why Zika virus hijacks a protein needed for brain growth
A new study shows that the Zika virus hijacks a host protein called ANKLE2, which is important for brain development, to assist its own reproduction. Because Zika can cross the placenta, this can have disastrous consequences in pregnancy.
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T cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
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Researchers launch a pioneering project to study the human virome puzzle
The research, which will explore the universe of viruses living in the human body, is fueled by a $20-million grant from the National Institutes of Health.