All Viruses articles – Page 8
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A new vaccine approach could help combat future coronavirus pandemics
Researchers are able to create a mosaic nanoparticle vaccine - mosaic-8, based on the sarbecovirus receptor-binding proteins (RBDs), which would help combatting SARS-CoV-2 variants and other coronavirus subtypes.
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A therapeutic HPV vaccine could eliminate precancerous cervical lesions
A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial.
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Viruses and the human cell: The evolutionary arms race
Researchers have discovered a unique genetic mechanism that provides cells with rapid and efficient protection against viruses. The findings could lead to the development of new therapeutics.
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Scientists discover molecular ‘fingerprint’ of Long Covid in children’s blood
A new study has highlighted the molecular signature of Long Covid in plasma in paediatric age and used an AI tool capable of making the diagnosis based on the results of the blood sample with 93% accuracy.
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Ultrasensitive test detects, serially monitors intact virus levels in patients with COVID-19
A highly sensitive approach, adapted from cancer vesicles detection, was discovered to be able to detect SARS-CoV-2 viral particles in fluid samples of patients with acute COVID-19 infections.
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Hepatitis B is a problem for a growing number of patients on immunosuppressive medications
The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.
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Antiviral protein causes genetic changes implicated in Huntington’s disease progression
A new study shows APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, are unusually active in the brains of Huntington’s patients.
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New study finds social programs could reduce the spread of HIV by 29%
Researchers have found that addressing barriers to HIV care from depression, homelessness, individual and neighborhood poverty, education disparities, lack of insurance and unemployment could reduce the national HIV incidence by 29% over 10 years.
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Scientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
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Towards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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A Marburg virus outbreak was confirmed in Tanzania
WHO has announced that an outbreak of Marburg virus disease in Tanzania has been confirmed, with 25 suspected cases. Outbreak control measures have been established since the announcement.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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WHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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Ancient viral DNA shapes early embryo development
Over half of our genomes consists of remnants of ancient viral DNA which are widespread across the tree of life. Once dismissed as the ’dark side’ of the genome, researchers have now revealed the role of transposable elements in early embryo development.
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Valneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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Research team receives $1.5 million to study neurological disorders linked to long COVID
A significant grant was awarded for an upcoming research of cellular and molecular mechanisms in the neurological challenges posed by long COVID-19.
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Tiny vortices help detect dangerous viruses
Due to the specific wavelengths of vibrations used to create these tiny whirlpools, they efficiently trap cells, bacteria and other larger bioparticles found in saliva while leaving antibodies and viruses free to flow forward through multiple biosensing chambers.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.