All Viruses articles – Page 29
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New viral strain induces immunogenic cell death in tumour cells
A study has developed a new strain of vaccinia virus, which can replicate in tumour cells while maintaining increased immunogenicity. Specifically, it can to induce so-called immunogenic cell death in tumour cells.
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Researchers develop experimental mRNA avian flu vaccine
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models, according to a new study.
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'Failed drug' could offer new approach to Epstein-Barr virus and resulting diseases
Researchers have found that the Epstein-Barr virus triggers infected cells to ramp up the production of an enzyme known as IDO1, a discovery that offers a promising starting point for putting the brakes on EBV.
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Virocells: How the ‘home’ environment influences microbial interactions
Research into ocean virocells - bacteria infected by viruses, thus forming a new organism - has yielded fascinating new insights about how this merger of microbes affects, and is affected by, real-world surroundings.
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Biotech companies leverage novel tools to develop drugs for RSV
Reporter structures that can be introduced into cells for use in drug screening assays emit fluorescent or bioluminescent light at different intensities when RSV genes are inhibited by the potential antiviral agents being tested.
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Mimicking infection in pregnant mice provokes persistent changes in juvenile brains
No parent wants to risk their child having a serious infection, least of all while still in the womb, but did you know that the immune response to a viral infection during pregnancy could also affect the development of the unborn offspring? Scientists from Harvard University in ...
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Rabies outbreaks in Costa Rica cattle linked to deforestation
Deforestation in Costa Rica raises the risk of cattle becoming infected with rabies by vampire bats, finds a new study.
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Scientists sequence rabies genome in black bear
Researchers have published their findings after they sequenced the entire genome of the virus and compared it with existing rabies sequences from other animals.
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Ancient viral DNA in the human genome linked to major psychiatric disorders
New research led by King’s College London has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to susceptibility for psychiatric disorders such as schizophrenia, bipolar disorder, and depression. Published in Nature Communications, the study was part-funded ...
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Drug-like inhibitor shows promise in preventing flu
Scientists have developed a potential drug-like molecule that blocks the first stage of type A influenza infection.
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HPV testing for cervical cancer may be safe at longer intervals than recommended by current guidelines
The risk of detecting cervical precancer eight years after a negative HPV screening was found to be similar to the risk after three years (the commonly recommended screening interval) after a negative cytology screening.
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New tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious infections.
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Researchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.
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Sea zombies: Viruses keep the most common marine bacteria in check
The ocean waters surrounding the German island of Helgoland provide an ideal setting to study spring algae blooms, a focus of research at the Max Planck Institute for Marine Microbiology since 2009. Source: Jan Brüwer/Max Planck Institute for Marine Microbiology Sunset over the island of Helgoland in ...
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Scientists harness plant viruses to deliver genome editing reagents in diverse plant species
The use of viral vectors to deliver genome editing components offers potential solutions to many current technical bottlenecks involved in genome editing in plants.
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A trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
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Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, new studies show
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week.
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Study provides new insights into phage therapy design
Results from a new study are providing new insights into the therapeutic potential of bacteriophage (phage) therapy for treating diseases like cystic fibrosis (CF).
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H5N1 virus from 2022 mink outbreak capable of inefficient airborne transmission
New research reveals that a member of the H5N1 family of influenza viruses evolved very limited ability to transmit via respiratory droplets.
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Study paves the way for an active agent against hepatitis E
Tests in cell culture with human liver cells showed that the compound K11777 prevents infection with hepatitis E viruses.