All Viruses articles – Page 2
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Study reveals how dengue rewires the immune system, reshaping vaccine response
Just as a computer’s operating system can be rewritten after a major update, dengue infection can ‘re-programme’ the body’s immune system, leaving a long-lasting genetic imprint that influences how people respond to future infections—an effect not seen with vaccination.
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Scientists unveil viral mechanism behind nasopharyngeal cancer spread
Researchers have discovered that the Epstein-Barr virus (EBV), a common human virus closely linked to nasopharyngeal carcinoma (NPC), can change the 3D structure of the human genome inside cancer cells, much like assembling building blocks.
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A survival kit for smallpox viruses
Scientists have discovered a previously unknown type of assembly chaperone during their analysis of poxviruses, and they have decoded its function in full detail. This is the first known chaperone that is not formed by a protein but by a nucleic acid — specifically RNA.
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Researchers map key human proteins that power coronavirus replication, pointing to new treatment strategies
Scientists have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.
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Gray seals perplex scientists with lack of response to flu infection
Something strange happens when two kinds of seals living in the waters around Cape Cod get infected with influenza – harbor seals get sick but gray seals don’t. This perplexing phenomenon led scientists to investigate if a difference in a piece of the immune system called cytokines could be responsible for this difference.
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Protein discovery gives new hope for longer COVID protection
Scientists have discovered that the body’s immune system strongly reacts to an internal protein from SARS-CoV-2, the virus that causes COVID-19, which mutates less frequently than the surface-spike protein currently targeted by vaccines.
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Antibody-making cells reveal new function in response to flu infection
A study has uncovered a new function of the immune cells that are known for making antibodies. Researchers determined that, in response to flu infection, a specialized set of B cells produce a key signaling molecule that the immune system needs to develop a robust, long-term response to fight off infections.
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Infectious disease modelling teams invited to strengthen global response to highly pathogenic avian influenza
An international modelling challenge is calling on experts across disciplines to help tackle one of Europe’s most pressing health threats: highly pathogenic avian influenza (HPAI). The initiative, which is now open for applications, seeks to improve outbreak modelling readiness and to foster international collaboration among researchers and decision makers.
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CARB-X to support lower respiratory tract infection diagnostic by Zeteo
CARB-X has awarded Zeteo Tech, Inc. US$1M to execute a workplan for its noninvasive diagnostic platform that aims to evaluate whether exhaled breath can diagnose lower respiratory tract infections (LRTIs) in high-risk populations within critical care environments.
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Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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Study suggests link between hepatitis B immunity and lower risk of developing diabetes
A research study shows that overall HBV immunity is linked with a 15% lower risk of diabetes, with higher protection in younger people and those with higher immunity shown by higher antibody levels.
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Zoo poo might hold the secrets to new medical treatments
Scientists are hoping the collection of poo from tigers, elephants, giraffes and other exotic animals, could contain the secret to finding new medical treatments. Although a waste product to the animals, hidden amongst it are thousands of phages which are potentially capable of fighting bacterial infections.
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‘Migrion’ – a chimeric structure of virus and migrasome, a novel unit for intercellular viral transmission
Researchers found that in infected cells, nucleic acids and proteins of vesicular stomatitis virus (VSV) are actively transported into migrasomes, newly characterized cellular structures generated specifically during cell migration.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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Guideline on respiratory infections in leukemia revised
People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections.
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MERIT grant awarded to study cure for HIV
A scientific team has received an NIH MERIT Award to provide long-term grant support to study a handful of people who have managed to clear HIV after a stem cell transplant and those who did not.
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Next-generation ‘molecular scissors’ may offer hope for chronic hepatitis B sufferers
Researchers have developed engineered precision ’molecular scissors’ that can permanently disable the genetic blueprint of the hepatitis B virus (HBV). The approach directly targets covalently closed circular DNA (cccDNA), the stubborn viral reservoir.
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Ancient viruses in human genomes offer new avenue for stopping cancers, autoimmune diseases, and more
Researchers have revealed the first three-dimensional structure of a protein from an ancient human endogenous retrovirus (HERV) found within the human genome.
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Seroprevalence 36 months after a single-dose bivalent HPV vaccination among nine to fifteen-year-old girls
A single-dose bivalent HPV vaccine induces sustained immunity in Bangladeshi adolescent girls, with lower HPV16 seropositivity among older girls and those in higher grades, with higher HPV18 seropositivity linked to lower household income.