All Vaccinology articles – Page 7
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NewsEffectiveness of updated COVID-19 vaccines wanes moderately over time, is lower against currently circulating variants
New research shows boosters targeting omicron subvariants of SARS-CoV-2 are still providing reasonably durable protection against infection, hospitalization and death from COVID-19, but are less protective against the JN.1 strain.
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NewsResearchers take step toward development of universal COVID-19 antibodies
Scientists have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.
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NewsScientists uncover factors potentially contributing to the decline of the mpox outbreak
Researchers hypothesise that it is not likely that preventive vaccination was a driver of the outbreak’s decline in the Netherlands, as the mpox incidence started to decline before the start of the vaccination programme.
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NewsVaccine development program aims to prevent sepsis in newborns
Researchers have been awarded $3.96 million to develop a maternal vaccine that prevents sepsis caused by Klebsiella pneumoniae in newborns and infants.
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NewsNew viral strain induces immunogenic cell death in tumour cells
A study has developed a new strain of vaccinia virus, which can replicate in tumour cells while maintaining increased immunogenicity. Specifically, it can to induce so-called immunogenic cell death in tumour cells.
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NewsResearchers develop experimental mRNA avian flu vaccine
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models, according to a new study.
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NewsCentury-old vaccine protects type 1 diabetics from infectious diseases
Research shows that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
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NewsDrug-like inhibitor shows promise in preventing flu
Scientists have developed a potential drug-like molecule that blocks the first stage of type A influenza infection.
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NewsNew tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious infections.
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NewsResearchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.
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NewsHow vaccine messaging is framed makes a difference, new research reveals
A one-size-fits-all approach to communicating the benefits of vaccines isn’t effective. Message framing plays a crucial role depending on the mindset, so it requires communicating in different ways for different people, a new study says.
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NewsLong-term protection from SARS-CoV-2 variants in mice by a Phase II clinically evaluated original mRNA vaccine booster
A new study discusses the development of an mRNA vaccine (LVRNA009) that encoded the S protein of the Wuhan-Hu-1 strain and evaluated the long-term protection potential against SARS-CoV-2 variants.
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NewsA trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
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NewsAdvances in priming B cell immunity against HIV pave the way to future HIV vaccines, new studies show
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week.
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NewsHPV vaccine prevents most cervical cancer cases in more deprived groups, major study shows
The human papillomavirus, or HPV, vaccine is cutting cases of cervical cancer right across the socio-economic spectrum, with most cases being prevented in more deprived groups, according to a major study funded by Cancer Research UK. Source: NIAID Colorized electron micrograph of HPV virus particles harvested and ...
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NewsBiophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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NewsBirth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease.
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NewsGPS-like system shows promise as HIV vaccine strategy to elicit critical antibodies
Researchers have developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
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NewsUT Health San Antonio to lead $11m study of a first-ever oral chlamydia vaccine
The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a cooperative agreements research project grant.
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NewsA third Covid vaccine dose improves defence for some clinically extremely vulnerable patients
A major clinical trial has found that an additional COVID 19 vaccine dose led to the majority of clinically extremely vulnerable people mounting defensive antibodies against Covid-19.
