All Vaccinology articles – Page 17
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Different Covid antibodies target distinct regions of spike protein
Researchers found that Covid antibodies can be categorized into three types, each targeting distinct regions of the viral spike protein, a key component of the vaccine antigen.
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New typhoid conjugate vaccine Bio-TCV® approved in Indonesia
Bio Farma’s Bio-TCV® typhoid conjugate vaccine (TCV) has been licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.
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Live shingles vaccine still protecting 10 years on - despite waning effectiveness
The effectiveness of live zoster (shingles) vaccine is highest in the first year after vaccination and then wanes substantially, but it continues to provide some protection against shingles ten years after vaccination.
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Research partnerships to improve access to vaccines in low and middle-income countries
Four new research hubs that will address challenges of vaccine manufacturing and delivery in developing countries have been announced.
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Learning more about how flu strains evolved may help guide future vaccine development
Researchers studying the evolutionary history of flu viruses have found that a new quantitative analysis of how they evolved may help predict future strains.
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Researchers develop a nasal vaccine that prevents COVID in preclinical studies
New protein-based technology triggers immunity to respiratory pathogens in the airway, before the disease reaches the bloodstream.
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Study supports potential for injectable ‘chemical vaccine’ for malaria using atovaquone
Researchers demonstrate in mouse model that key mutation that renders malaria parasites resistant to atovaquone also makes them non-transmissible via mosquitoes.
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Promising results from E coli-produced HPV vaccine trials in female volunteers
Researchers conducting human trials of an E. coli-produced 9-valent HPV vaccine candidate found it was well tolerated and immunogenic, warranting further efficacy studies in larger populations.
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Study finds increased risk of Guillain-Barré after COVID-19 infection
Having a COVID-19 infection is associated with an increased risk of developing the rare disorder called Guillain-Barré syndrome within the next six weeks.
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Single vaccine protects against three deadly strains of coronavirus
A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies.
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Researchers unlock power of genetic glycoengineering to advance vaccine tech
A novel glycoengineering platform is poised to revolutionise future production of vaccines and therapeutics to fight infectious diseases.
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Clinical trial finds live vaccinations safe for liver and kidney transplant recipients
Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions.
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Study reveals how young children’s immune systems tame SARS-CoV-2
A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.
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Coronavirus vaccination reveals that body builds immune memory in organs
A study of the mRNA coronavirus vaccines reveals that the human body builds local immune memory in various organs. The immune memory cells are more numerous in the organs than in the blood and have enhanced antiviral defense functions.
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TB vaccine discovery paves path to end no. 1 killer of people living with HIV
Scientists have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV.
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New UK projects to kickstart future vaccine development awarded £25m
Three UK projects designed to build our understanding of viruses and how the immune system reacts to different challenges will share £25m in new funding from UKRI.
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Vulnerability to different COVID-19 mutations depends on previous infections and vaccination
A person’s immune response to variants of SARS-CoV-2 depends on their previous exposure – and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection.
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Nasal vaccine could be the new line of defence against Strep A
As Streptococcus A cases continue to be prevalent in Queensland and internationally, a new nasal vaccine could provide long-term protection from the deadly bacteria.
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Single vaccine shot could thwart eight hospital superbugs
A single dose of an experimental vaccine, administered in mouse models, can provide rapid protection against eight different bacteria and fungi species.
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Scientists discover alternative base modification for mRNA therapeutics
Researchers have incorporated a newly discovered base, called base Z, into mRNA to create Z-mRNA that has improved translational capacity, decreased cytotoxicity and drastically reduced immunogenicity compared to unmodified mRNA.