All Vaccinology articles – Page 16
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Researchers ID opportunities to improve future HIV vaccine candidates
An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study.
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Researchers pave way for next generation COVID-19 immunization strategies
A vaccine booster delivered directly to mucosal site of infection enhances protection against COVID-19 infection in non-human primates, a new study reveals.
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Risk of death reduces after COVID-19 vaccine but protection wanes after six months
The risk of death from COVID-19 decreases significantly after vaccination but this protection diminishes after six months, providing evidence for continued booster doses, a new study has found.
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Mpox vaccine triggers equally strong immune response in smaller doses
Delivering the two-dose mpox vaccine in smaller than the usual FDA-approved doses produced a detectable immune response. This also occurred regardless of whether people were living with or without HIV.
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Researchers develop a novel dry-powder inhaled vaccine platform
Researchers have developed a single-dose, dry-powder, inhalable vaccine platform using nano-micro composite multilevel structures, which is effective in blocking respiratory viral infection and transmission in animal models.
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Researchers develop potential vaccine against antibiotic-resistant enterococci
Researchers have discovered how to create an enterococcal vaccine that is relatively easy to produce and takes advantage of membrane vesicles.
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COVID-19 vaccine candidates show robust boosting potential
Two COVID-19 vaccines have shown strong potential to be an improved approach for boosting immunity to SARS-CoV-2 variants according to interim results of a Phase 1 clinical trial.
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Patients can pause immune-suppressing medicines for COVID-19 booster vaccine
A major clinical trial shows that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine.
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Scientists find new, better way to develop vaccines
Researchers have developed a new system to display epitopes in mammal cells for immunization studies and believe that this method can help scientists greatly in immunization efforts.
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First results in using new tools to tackle respiratory syncytial virus
Vaccines for pregnant women and use of monoclonal antibodies have been approved for use in the European Union to prevent respiratory syncytial virus (RSV) among young children. Are those tools working?
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Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses
Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body, and have found a way to prevent ‘off-target’ immune responses.
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Scientists develop needle-free patch vaccine to protect against Zika virus
A simple-to-apply, needle-free vaccine patch has been developed to protect people from the potentially deadly mosquito-borne Zika virus.
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Biomineralized bacterium acts as in-situ vaccine producer
A new type of bacteria-based autologous cancer vaccine uses calcium carbonate (CaCO3) biomineralized Salmonella (Sal) as an in-situ cancer vaccine producer and systematical ITM regulator.
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Researchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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Infants exposed to certain biologics during pregnancy can safely receive rotavirus vaccine
New research in Canada may prompt a change to vaccination guidelines for infants. Researchers investigated how the immune systems of babies exposed to biologic agent medications during pregnancy are affected.
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Spike in premature births caused by COVID, and halted by vaccines
COVID-19 caused an alarming surge in premature births, but vaccines were key to returning the early birth rate to pre-pandemic levels, according to a new analysis of California birth records.
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Vaccine created to prevent dangerous tropical disease receives FDA approval
The US Food and Drug Administration (FDA) has approved the world’s first vaccine against the chikungunya virus – Ixchiq.
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COVID vaccination before infection strongly linked to reduced risk of developing long covid
Unvaccinated individuals are almost four times as likely to be diagnosed than those vaccinated before first infection, new research shows.
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Scientists boost vaccines with machine learning to drive more effective treatments
Machine learning guided the discovery of new immune pathway-enhancing molecules and found one particular small molecule that could outperform the best immunomodulators on the market.
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Fourth dose of COVID vaccine boosts protection in patients with rheumatic disease
A new study suggests that the recommendation for patients receiving disease-modifying antirheumatic drugs to receive a fourth dose of the mRNA vaccine has saved lives and reduced hospitalizations among patients in this high-risk group.