All Vaccinology articles – Page 15
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NewsResearch reveals why staph vaccine candidates keep failing - and how to fix the problem
Research from UC San Diego explains the clinical failure of dozens of candidate vaccines for one of the most common human infections; it also suggests a way to fix the problem.
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NewsPriming vaccine tested by global project lays path to HIV vaccine
A global project is attemptng to discover a HIV vaccine based on germline targeting and that is practical for those in Low and Middle-Income Countries.
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NewsCOVID-19 vaccine reduces long COVID in children
Researchers have found that vaccination of children provides moderate protection against long COVID. Vaccination also has a stronger effect in adolescents, who have a higher risk of developing long COVID than young children.
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NewsFirst all-UK study of 67m people reveals consequences of missed COVID-19 vaccines
The first research study of the entire UK population highlights gaps in COVID-19 vaccine coverage. Between a third and a half of the population had not had the recommended number of COVID vaccinations and boosters by summer 2022.
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NewsResaerchers design thermostable vaccine candidate for SARS-CoV-2 variants
Researchers report the design of a synthetic antigen that can be manufactured as a potential COVID-19 vaccine candidate - it is effective against all current strains of SARS-CoV-2 and can be quickly adapted for future variants as well.
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NewsSmallpox vaccine induces immunity against monkeypox infection in people living with HIV
Researchers have shown that intradermal vaccination with the JYNNEOS vaccine against smallpox is the best option to protect people living with HIV from contracting the monkeypox virus.
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NewsNasal spray with antibodies could prevent COVID-19
Researchers have shown that nasal drops with IgA antibodies can protect mice from SARS-CoV-2 infection.
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NewsFirst-in-human vaccine trial for deadly Nipah virus launched
The University of Oxford has launched a new clinical trial to test a vaccine to protect people against deadly Nipah virus. The first clinical trial participants received doses of the ChAdOx1 NipahB vaccine over the last week.
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NewsSickle cell raises COVID-19 risk, but vaccination lags
Adults with sickle cell disease around half as likely to have had initial doses as people without sickle cell disease, a study in Michigan shows.
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NewsPotential nasal COVID-19 vaccine candidate offers better and longer protection
Study shows that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness.
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NewsValneva vaccinates first participant in pediatric trial of single-shot Chikungunya vaccine
Valneva SE has announced that the first participant has been vaccinated in the Phase 2 clinical trial evaluating the safety and immunogenicity in children of two different dose levels of Valneva’s single-shot chikungunya vaccine.
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NewsVaccine boosts innate immunity in people with dormant immune cells
Epigenetic cell states predict whether or not an individual profits from the “wake-up call” to the innate immune system that is provided by the BCG vaccine.
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NewsCOVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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NewsWHO prequalifies a second malaria vaccine
WHO has added the R21/Matrix-M malaria vaccine to its list of prequalified vaccines.
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NewsStudy reveals clues to how Eastern equine encephalitis virus invades brain cells
An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.
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NewsSimplified formulation of oral cholera vaccine, licensed by Korean regulatory agency
Euvichol-S, a simplified formulation of oral cholera vaccine, has been licensed by Korean regulatory agency, and is expected to alleviate global cholera vaccine shortages.
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News“Honey, I shrunk the cookbook” – new approach to vaccine development
Bioinformaticians have presented a method for identifying epitopes that promise safe immunisation across the broadest possible population group.
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NewsNew study explores malaria invasion to help develop life-saving vaccine
An innovative project investigates the progression of malaria infection and the role of the parasite to better aid the development of an effective malaria vaccine and significantly reduce rates of deaths from the disease.
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NewsB cell deficient patients gain protective T cell immunity after SARS-CoV-2 vaccination, infection
Researchers found that vaccinated B cell-deficient individuals had significantly reduced risk of moderate and severe disease in comparison to those who were not vaccinated, despite an absence of anti-spike antibody responses.
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NewsResearchers to develop vaccine candidates against Marburg viruses
The multidisciplinary European consortium MARVAX will receive 7.4 million euros over the next four years for the research and development of vaccines against Marburg viruses.