All Vaccinology articles – Page 14
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Fusion protein reveals a conservative antigenic domain across herpesviruses
A new study proposes that the gB DII domain within the herpesvirus family constitutes a broadly conserved neutralizing epitope structural domain.
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COVID vaccine during pregnancy improves neonatal outcomes
A study has found that neonates of booster-vaccinated mothers had less risk of being infected with COVID-19 compared to those of unvaccinated mothers. Neonates of unvaccinated mothers died twice as frequently as those of vaccinated mothers.
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SK bioscience’s typhoid conjugate vaccine achieves WHO prequalification
SK bioscience and the International Vaccine Institute (IVI) announced that the typhoid conjugate vaccine developed by SK bioscience with technology transfer from IVI has achieved the World Health Organization prequalification (PQ).
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Scientists craft enhanced viral structure in VLP vaccines through polymer restructuring
Researchers reported a viromimetic polymer nanoparticle vaccine (VPNVax), crafted by rearranging the RBD proteins of the coronavirus and modifying them onto the surface of pre-assembled polyethylene glycol-polylactic acid polymer nanoparticles.
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PD-1-enhanced DNA vaccine achieves 6-year cART-free AIDS prevention and virologic control
Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model.
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Studies find flu vaccines were effective in 2022-2023 flu season
Two recent studies have found that flu vaccines were effective for all ages against both moderate and severe flu in the U.S. during the 2022-2023 flu season.
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High vaccination coverage key against expected increase of measles cases in Europe
In 2023, significant increases in the number of measles cases and outbreaks were observed globally, including in 40 of the 53 countries of the European region, and in at least ten EU/EEA countries.
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Vaccine shows promise against CMV, a virus that causes birth defects
An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, a study reveals.
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Researchers offer new insights into how antibodies function against HSV
Findings from a new study offer insights into how antibodies function in combating herpes simplex virus (HSV) infections. Their research may lead to possible new treatments for neonatal herpes.
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UK urges vaccination as measles surge, man dies in Ireland
The UK government has urged parents to take up the offer of MMR vaccination for their children amid a surge in measles cases. Source: CDC and NIAID Colorized transmission electron micrograph of a measles virus particle (red). Since the last update a week ago, a further 118 ...
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Prior zika infection increases risk of subsequent severe dengue and hospitalization
A study suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
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Dengue vaccine protects 79.6% of those vaccinated, study shows
The single-dose Butantan-DV dengue vaccine prevents development of the disease in 79.6% of those vaccinated, according to a new study.
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Scientists spot an ultra-fast movement on surface of HIV virus
Investigators catch ultra-fast HIV docking mechanism in the act, giving them a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine.
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DNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
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Real life data reveals success in controlling respiratory syncytial virus
Early data after passive immunisation with a monoclonal antibody against severe respiratory syncytial virus in 2023 show a decline in hospitalisations and length of stay especially in the most vulnerable group of infants under the age of six months.
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Single dose typhoid conjugate vaccine (TCV) provides lasting efficacy in children
A single dose of the typhoid conjugate vaccine, Typbar TCV®, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study.
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AiCuris and DZIF sign Collaboration and License Option Agreement
AiCuris Anti-infective Cures AG and the German Center for Infection Research (DZIF) have announced the signing of a collaboration and license option agreement.
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HIV antibodies protect animals in proof-of-concept study
Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.
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New study to examine very rare adverse events linked to COVID-19 vaccines
A multimillion-dollar global initiative will study causes and risk factors, to ensure safer vaccines are ready for the next potential pandemic.
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Vaccine speeds up the production of antibodies against Covid
A new vaccine uses preexisting immunity to a separate virus (the influenza virus) to help kickstart the process of making antibodies against SARS-CoV-2.