All Vaccinology articles
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NewsNeonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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NewsMass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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NewsResearchers review strategies for the modification of vaccinia virus towards a better vaccine vector
A new review delineates the commonly targeted viral genes for attenuation during vaccinia virus (VACV) vector modification and provides an overview of the progress in VACV-vectored vaccine development.
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NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
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NewsBreakthroughs in TB vaccine and drug development pave way for global health advancements
An international team of researchers unveils groundbreaking progress in TB vaccine development and therapeutic innovations, offering hope to curb the disease’s devastating impact.
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NewsResearchers take step towards creating Salmonella vaccine
A study of a new method to deliver a Salmonella vaccine found that when tested with real-world strains of Salmonella, the vaccine created antibodies against this microbe in the mice – which equips the animals with a defense mechanism against the pathogen.
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NewsNasal COVID-19 vaccine to enter US clinical trials
A nasal vaccine for COVID-19 is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA).
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NewsGroundbreaking Ebola vaccination trial launches in Uganda
In a global first, Uganda’s Ministry of Health, the World Health Organization (WHO) and other partners have launched a first ever vaccine trial for Ebola from the Sudan species of the virus, and at an unprecedented speed for a randomized vaccine trial in an emergency. Source: CDC Global ...
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NewsNew method offers faster response to new virus variants
Researchers present a promising approach for swift identification of mutations that are crucial for the immune escape that enables the rapid adaptation of vaccines to new virus variants. It is based on a previously established method called mutational scanning.
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NewsWHO and partners enable access to candidate vaccine and treatments for outbreak of Sudan Ebola virus disease in Uganda
WHO and partners have immediately boosted their support to the Ugandan government’s response to an outbreak of Sudan virus disease outbreak (SVD, part of the Ebola family), including by facilitating access to a candidate vaccine and candidate treatments.
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NewsAntibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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NewsMost Americans favor school vaccination requirements, but support is rising for opt-out options
A new survey finds that nearly three-quarters of U.S. adults support requiring that children be vaccinated against preventable diseases such as measles, mumps, and rubella.
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NewsFrom Fox News to MSNBC: Diverse media diet linked to higher trust in vaccines
People who get their news from an ideologically diverse array of sources are more likely to get vaccinated, regardless of their political affiliation, new research shows.
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NewsA therapeutic HPV vaccine could eliminate precancerous cervical lesions
A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial.
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NewsValneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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NewsChain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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NewsNew research provides insight into reduced COVID-19 vaccine efficacy in lupus patients
A recent study provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases, highlighting that lupus patients may require tailored vaccination strategies.
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NewsHepatitis E vaccination is effective in an epidemic
A case-control study has proved the effectiveness of the two-doses Hecolin vaccine against a potential hepatitis E outbreak.
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NewsPromising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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NewsT cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
