All Vaccinology articles
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TB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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Research identifies key antibodies for development of broadly protective norovirus vaccine
A new study identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly effective norovirus vaccine, as well as the development of new therapeutic antibodies.
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BAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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New antibodies show potential to defeat all SARS-CoV-2 variants
Researchers discovered that a paired combination of antibodies binding to the two domains of the SARS-CoV-2 viral particle showed promising results in elimination of all virus variants caused in the COVID-19 pandemic.
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Scientist who deployed glowing stars to detect disease named fellow of the Royal Society of Chemistry
The man who turned the science of glow-in-the-dark stars into ways to detect disease, Professor Richard Willson, has been elected as a fellow of the Royal Society of Chemistry.
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New COVID-flu vaccine platform could provide broad, lasting protection
Researchers have developed a new vaccine platform that could provide more robust, longer-lasting protection from both COVID-19 and influenza, and broader immunity to different flu strains.
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Recommendations announced for influenza vaccine composition for the 2025-2026 northern hemisphere influenza season
The World Health Organization (WHO) has announced the recommendations for the viral composition of influenza vaccines for the 2025-2026 influenza season in the northern hemisphere.
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New test identifies prior infection by zika virus and all four dengue virus serotypes
An alternative approach is developed to detect and distinguish between antibodies induced by the dengue and zika virus in blood samples. The strategy can be used to orient public health policy and evaluate the efficacy of dengue vaccines.
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From dormant to danger: How VZV reactivation is driving CNS infections
Researchers conducted a comprehensive study spanning 10 years (2013–2022), to identify the VZV-related infections affecting the central nervous system. Their study reveals a marked increase in adult VZV-related CNS infections, particularly since 2019.
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Interventions could eliminate transmission of hepatitis B from mothers to babies in Africa
Researchers at the University of Liverpool have conducted a large-scale analysis that sheds light on the critical steps needed to combat the vertical transmission of chronic hepatitis B virus (HBV) in Africa. Source: Solasly A baby in the womb of its mother being held by its mother and ...
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Flu vaccine offers moderate protection against strains dominant in most European countries in 2024/2025
According to interim analysis of influenza vaccine effectiveness for the 2024/2025 season in Europe, the vaccine offered moderate protection against dominant influenza A strains, and strong protection against influenza B.
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Experts recommend mAb protection against RSV as standard care for all infants
While RSV poses a serious threat to the health of infants and young children, prophylactic mAbs offer safe and effective protection for an entire season, according to international health organizations.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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As dengue spreads, researchers discover a clue to fighting the virus
Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study. Most children who experienced two or more dengue infections showed very minor symptoms—or no symptoms at all—when they caught the virus again.
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Promising antibody may prove useful against deadly Ebola virus outbreaks
New research reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.
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Kingdom of Saudi Arabia confirms US $500 million commitment to global polio eradication effort
The Kingdom of Saudi Arabia has reaffirmed its US $500 million pledge to the Global Polio Eradication Initiative (GPEI) in a signing event during the fourth Riyadh International Humanitarian Forum.
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Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials. The mRNA vaccine was successful in triggering an immune defence response that helped to reduce TB numbers in infected mice.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Mass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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Researchers review strategies for the modification of vaccinia virus towards a better vaccine vector
A new review delineates the commonly targeted viral genes for attenuation during vaccinia virus (VACV) vector modification and provides an overview of the progress in VACV-vectored vaccine development.