All USA & Canada articles – Page 73
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Potential nasal COVID-19 vaccine candidate offers better and longer protection
Study shows that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness.
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Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
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Zika virus is effective when used to treat a type of childhood cancer in mice
Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a new study.
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Novo Nordisk Foundation partners with CARB-X to fight drug-resistant infections
The Novo Nordisk Foundation is committing up to $25 million to support the early-stage development of innovative tools to prevent, diagnose and treat the most dangerous drug-resistant bacterial infections. The three-year grant will go to the Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), the leading global non-profit public-private partnership in this ...
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Researchers decode the ‘cytokine storm’ in sepsis
The team found that three cytokine pairs were responsible for most of the body’s damaging response to sepsis.
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COVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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Researchers discover molecular ‘barcode’ used by bacteria to secrete toxins
Researchers have discovered a molecular “barcode” system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
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Researchers unmask an old foe’s tricks to thwart new diseases
Researchers are studying Yersinia pestis, the bacterium that causes bubonic and pneumonic plague, to better understand its ability to evade the immune system and apply that understanding to control other pathogens.
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New approach could address antibiotic resistance to Mycobacterium abscessus
Scientists have designed new versions of the drug spectinomycin that overcome efflux, the main mechanism driving resistance.
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Soil fungi may help explain the global gradient in forest diversity
Mycorrhizal fungi appear to be counteracting the effects of harmful soil pathogens in ways that influence global patterns of forest diversity.
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Researchers identify why cancer immunotherapy can cause colitis
Studies in mice reveal the mechanism that induces this severe side effect and point to a solution that kills the cancer without causing gastrointestinal issues.
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Novel compound protects against infection by virus that causes COVID-19
Compounds that obstruct the “landing gear” of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19.
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Calibr announces license agreement with Gilead to develop long-acting HIV antiviral agent
Long-acting combination HIV regimens have the potential to transform the future of coordinated HIV clinical care
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Single-point testing could miss cases of asymptomatic malaria
Dynamic, fluctuating levels of this parasite in people without symptoms argues against single-point testing to diagnose infections, a new study suggests.
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Molecular link IDed between gut bacteria and excitatory brain signaling in C. elegans
A new study establishes a molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.
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Microbial awakening shifts high-latitude food webs as permafrost thaws
A new study shows that fungi are replacing plants as the primary energy source for Arctic and boreal animals.
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Scientists discover how environmental microbes boost fruit fly reproduction
A research group finds that environmental microorganisms enhance oogenesis in fruit flies, increasing the production of germline stem cells and the number of mature eggs in females via hormonal pathways.
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Study shines light on resourceful ways bacteria thrive in the human gut
A survey of bacterial genomes highlights the arsenal of enzymes microbes use to produce energy in the oxygen-poor environment of the gut.
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A high-fat diet could make you vulnerable to harmful microbes, including Covid
A new study demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk.
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Advanced viral diagnostics tool closer to widespread use
Scientists have introduced a powerful NGS-based screening and surveillance system that can detect any virus that can potentially infect humans, known or unknown, with greater sensitivity and speed than other NGS platforms.