All USA & Canada articles – Page 65
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Researchers develop a new toolkit in fruit flies to study Zika virus
To study how Zika virus proteins hijack and disrupt host developmental pathways during infection and disease progression, scientists have generated a toolkit of transgenic flies expressing all ten Zika virus proteins.
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Refrigerate lettuce to reduce risk of E. coli contamination, researchers say
Leafy green vegetables are important sources of dietary fiber and nutrients, but they can harbor harmful pathogens. In particular, lettuce has often been involved in outbreaks of foodborne illness across the U.S. A new study from the University of Illinois Urbana-Champaign examines factors that affect E. coli ...
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New antibodies target “dark side” of influenza virus protein
Researchers have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored “dark side” of the neuraminidase (NA) protein head.
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Scientists discover a novel vehicle for antibiotic resistance
An antibiotic-resistance gene forms an unusual structure that may provide constant protection against tetracycline in a common gut bacterium.
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Researchers reveal how the SARS-CoV-2 virus acquires its spherical shape
Researchers report that when the M protein, which is adjacent to the spike protein on SARS-CoV-2, gets lodged in the membrane, it coaxes the membrane to curve by locally reducing the membrane thickness.
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New approach may prevent deadly intestinal disease in preemies
Scientists have found that an investigational protein replacement protected neonatal mice from necrotizing enterocolitis (NEC), a deadly intestinal disease that often strikes extremely premature infants.
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Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens.
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New disease testing component facilitates lower-cost diagnostics
Biomedical researchers have developed a new, less expensive way to detect nuclease digestion – one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.
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Mosquito thermal adaptation could shift patterns of disease spread under climate change
Thermal adaptation can determine their risk of transmitting mosquito-borne diseases and how this risk might change in the future as they respond to climates warming.
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Vaping can increase susceptibility to infection by SARS-CoV-2
Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a new study has found.
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BCG mechanism extends protection to beat influenza A
A new study uncovered a previously unknown mechanism that extends the BCG vaccine’s shield to combat influenza A virus—the most prevalent flu strain.
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Researchers team up to publish bile acid breakthrough
Scientists have uncovered a previously unknown way that the microbes living in our gut help to make bile acids.
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Space-grown antiviral drug successfully brought back to earth in private Varda Space capsule
Space-grown crystals of an antiviral drug have been brought to earth following the successful recovery of the capsule from Varda Space Industries’ W-1 mission.
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COVID vaccine during pregnancy improves neonatal outcomes
A study has found that neonates of booster-vaccinated mothers had less risk of being infected with COVID-19 compared to those of unvaccinated mothers. Neonates of unvaccinated mothers died twice as frequently as those of vaccinated mothers.
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Streams connected to groundwater show improved detoxification and microbial diversity
Streams with ample connections to shallow groundwater flowpaths have greater microbial diversity and are more effective at preventing toxic forms of metals—often products of upstream mining—from entering and being transported downstream.
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Mice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study.
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Copies of antibiotic resistance genes greatly elevated in humans and livestock
Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. The research shows bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance ...
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Complement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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New method detects pathogens faster and more accurately by melting DNA
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, producing results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
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Study of usefulness of lockdowns during epidemics identifies alternate solution
Researchers found that small nonpharmaceutical interventions can tip the optimal response between very different approaches to slowing viral spread and identified an alternate approach that has previously not been recognized as effective.