All USA & Canada articles – Page 4
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NewsCurrent antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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NewsNIH-sponsored trial of Lassa vaccine opens
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.
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NewsCOVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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NewsNew method uncovers dynamic microbial community in coastal sediments
Scientists utilises single celll genomics and cell staining approaches to investigate the respiratory rates and metabolic activities of the diverse microbial communities in low biomass aqautic environments, such as Maine’s coastal sediments.
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NewsNew CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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NewsStudy finds new targets needed for vaccine to prevent herpesvirus transmission to babies
Despite the lack of research on vaccines against congenital cytomegalovirus (CMV), a research has recently discovered that the virus is able to cause cross-placental transmission even with the absence of multple essential proteins, providing insights for future vaccine development.
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NewsA review of Clostridioides difficile infection and treatments
<i>Clostridioides difficile</i> is a serious nosocomial infection that could cause from mild diarrhea to fatal colitis. Here presents a general overview that describes the current and emerging treatment practices for the prevention of <i>Clostridioides difficile</i> infection and its recourrences.
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NewsOlder adults might be more resistant to bird flu infections than children
Previous exposures to seasonal flu strains could prime the immune system to produce antibodies against the current version of H5N1 avian influenza virus in older adults, whilst children would benefit more from H5N1 vaccinations.
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NewsNew CRISPRs expand upon the original’s abilities
By scouring through a massive bacterial metagenomic databases, researchers have discovered new CRISPR-Cas systems as efficient as the conventional one. One of the candidate system has found with the technological potential to expand its impact in research, biotechnology and medicine.
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NewsA study identifies ‘surprising’ cause of sargassum blooms in the Caribbean
A group of interantional researchers identified the cause of sargassum blooms in the tropical Atlantic Ocean using computer modelling. They have modelled the ocean currents, wind pattern and the growth conditions that help them thrive in the region.
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NewsCOVID-19 discovery opens door to new treatments for chronic lung problems
A discovery was made to understand how severe viral infections, like COVID-19 and flu could destroy the ability of immune cells to repair the tissue damage in lungs, causing long COVID and other chronic lung diseases.
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NewsResearchers develop method to identify dormant cells that carry HIV
A new method is developed that utilizes a fluorescent genetic switch to tag and trace the lineages of the HIV-infected cells, including the dormant ones. This system might help to develop target therapies for the infected immune cells.
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News2025 Gut Microbiota for Health World Summit to spotlight groundbreaking research
The 13th Gut Microbiota for Health World Summit, taking place March 15-16 in Washington, D.C., will reveal how cutting-edge research on gut microbiome science is being applied to clinical practice.
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NewsTecovirimat is safe but ineffective as treatment for clade II mpox
The antiviral drug tecovrimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial.
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NewsDrug may prevent COVID-19 in exposed people within households, major trial finds
An international clinical trial of the oral antiviral drug, ensitrelvir, which has been proved to prevent COVID-19 cases, was conducted and found to be very effective. The drug will be awaiting for approval before becoming widely available.
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NewsNew automated method increases the efficiency of bioactive natural product discovery
In light of the technological advancement in machine learning and bioinformatics tools, researchers developed a fully-automated and integrated platform that enables them to easily identify bioactive natural products in Streptomyces.
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NewsPromising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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NewsProfessor investigates how symbiotic groups - like corals and biofilms - can behave like single organisms
UNCG philosopher of biology Dr. Derek Skillings is the lead investigator on a new, three-year, $600,000 grant from the John Templeton Foundation for a study of the emergence and evolution of goal-directed behavior in collective entities.
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NewsResearchers announce breakthrough in next-generation polio vaccines
Researchers have taken a major step towards producing a more affordable and lower-risk polio vaccine using virus-like particles (VLPs). These particles mimic the outer protein shell of poliovirus, but are empty inside.
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NewsMeningococcal vaccine found to be safe and effective for infants in sub-Saharan Africa
A new global health study found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in young children beginning at 9 months of age.