All University of Pittsburgh articles
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Immunotherapy for gum disease? Study in mice shows promise
Delivering microparticles containing the immune-modulating compound CCL2 directly to the gums inhibited bone loss and sped up bone repair in a mouse model of periodontal disease, new research has found.
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US COVID-19 rates show oscillating waves every six months
COVID-19 cases in the U.S. have shown unexpected oscillating waves every six months between the southern states and the northern states and, to a lesser degree, from east to west, according to new research.
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Conscience announces top performers in open science challenge to design promising pan-coronavirus drugs
The nonprofit drug discovery biotech Conscience has released seven newly discovered promising early-stage molecules that could lead to a new treatment effective against all coronaviruses, not just SARS-CoV-2.
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Immune protection against tuberculosis reinfection driven by cells that dampen lung inflammation
The body’s first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, scientists report.
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Bacteria able to overcome cost of vancomycin resistance in lab setting
Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a new study.
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Scientists to investigate why men and women are hit by the flu differently
Turns out that there is a biological reason why women and men suffer viral infections like influenza differently – and a team of scientists are extending their research to better understand why and how to design better, possible sex-specific treatments.
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Study shows promise for a universal influenza vaccine
New research reveals a promising approach to developing a universal influenza vaccine — a so-called “one and done” vaccine that confers lifetime immunity against an evolving virus.
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Bird flu stays stable on milking equipment for at least one hour
Bird flu, or H5N1 virus, in unpasteurized milk is stable on metal and rubber components of commercial milking equipment for at least one hour, increasing its potential to infect people and other animals, report researchers.
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Study provides new insights into phage therapy design
Results from a new study are providing new insights into the therapeutic potential of bacteriophage (phage) therapy for treating diseases like cystic fibrosis (CF).
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From treatment to tap: discovering the secrets of pathogen survival in drinking water systems
Scientists at the University of Pittsburgh are investigating how some DWPIs can survive drinking water treatment processes and determine better treatment processes to stop them from entering the human body.
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Drug-resistant bacterium responds to phage-antibiotic combo therapy
A case study, which required emergency investigational new drug approval from the U.S. FDA, is one of only a handful that have used bacteriophage therapy to treat Enterococcus faecium infection.
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Scientists make first-ever observation of a virus attaching to another virus
No one had ever seen one virus latching onto another virus, until anomalous sequencing results sent a research team down a rabbit hole leading to a first-of-its-kind discovery.
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Vaginal film that dissolves in 30 days may offer HIV prevention method for women
A vaginal film designed to slowly dissolve over the course of 30 days is being put to the test for the first time in a study that aims to determine its feasibility and acceptability as a potential HIV prevention method for women.
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New research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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Rule-breaking anoxic bacteria infected with viruses
Researchers investigating why green and purple bacteria in northeast Washington didn’t obey the usual rules found they had genes in their metagenome that came from viruses.