All University of Pennsylvania articles
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Cases of whooping cough growing, but knowledge about it is lacking
Many in the public are not familiar with symptoms of whooping cough. Almost a third of respondents (30%) are not sure if pertussis is the same as whooping cough and not sure (30%) whether a vaccine exists to prevent it.
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Study uncovers first evidence of resistance to standard malaria treatment in African children with severe malaria
Researchers have uncovered evidence of partial resistance to artemisinin derivatives — the primary treatment for malaria — in young children with severe, or ’complicated’ malaria.
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mRNA vaccine created to prevent and treat C. difficile
The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.
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Long-term low-dose antiviral treatment benefits patients with eye disease and pain from shingles
Long-term, low-dose antiviral treatment reduces the risk for potentially vision-damaging bouts of inflammation and infection, as well as pain, which occur when shingles affects the eye, according to new research.
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Researchers uncover new infection-fighting molecules through ‘molecular de-extinction’
A new study has uncovered sequences for ancient antimicrobial agents in the genomic data of extinct species, offering new hope for the development of antibacterial, antifungal, and antiviral treatments.
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Comprehensive meta-analysis pinpoints what vaccination strategies different countries should adopt
A new paper offers the first comprehensive meta-analysis examining what types of vaccine intervention strategies have the greatest effect, and whether different intervention strategies work better in different countries.
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Researchers reveal how a bacterium supports healing of chronic diabetic wounds
New research shows that the bacterium, Alcaligenes faecalis (A. faecalis), can facilitate healing of hard-to-treat wounds among people with diabetes.
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Scientists pinpoint how a red seaweed reduces methane emissions from cows
New research into the microbiome of cattle rumen has implications for addressing a leading contributor to climate warming.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Researchers used machine learning to search for antibiotics in a vast dataset containing the recorded genomes of tens of thousands of bacteria and other primitive organisms, yielding nearly one million potential antibiotic compounds.
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False belief in MMR vaccine-autism link endures as measles threat persists
As measles cases rise across the United States and vaccination rates for the MMR (measles, mumps, rubella) vaccine fall, a new survey finds that a quarter of U.S. adults do not know that claims that the MMR vaccine causes autism are false.
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Knowledge is a factor in closing black-white COVID-19 vaccination gap
Early in the Covid-19 pandemic, Black Americans were more hesitant to take the Covid-19 vaccine than were White Americans. As the pandemic went on, however, the disparity in vaccination rates between Black and White adults declined. Source: Baltimore County Government People queueing to be vaccinated, 23 December 2020 ...
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Researchers develop experimental mRNA avian flu vaccine
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models, according to a new study.
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Malaria may shorten leukocyte telomeres among sub-Saharan Africans
Researchers have uncovered a potential role of malaria in shortening length of telomeres in white blood cells, known as leukocytes, across sub-Saharan Africa.
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Scientists deconstruct the structural elements of a lesser-known microbe
Researchers shed light on archea, a single cell microorganism, to discover how proteins determine what shape a cell will take and how that form may function.
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Study reveals how gut microbes can distinguish prion disease in deer
A new collaborative study sheds light on how chronic wasting disease in deer impacts the gut microbiome and provides a potential tool for disease surveillance.
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Researchers probe coral resilience in the face of climate change
A new paper reveals the complex and varied ways corals are adapting, or struggling to adapt, to the rapidly changing oceanic environment.
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COVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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Viral persistence and serotonin reduction can cause long COVID symptoms
Components of the SARS-CoV-2 virus remain in the gut of some long COVID patients, causing persistent inflammation, vagus nerve dysfunction, and neurological symptoms.
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Scientists develop mRNA vaccine against Lyme disease-causing bacteria
An experimental mRNA vaccine provides protection in preclinical animal models against infection from Borrelia burgdorferi, the bacterium that causes Lyme disease, according to new research.