All University of Michigan articles
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NewsGut bacteria engineered to act as tumor GPS for immunotherapies
Cancer researchers have engineered gut derived E. coli bacteria to express immune-activating cytokines on their surfaces, with the idea that the bacteria would move into tumors and induce potent immune responses.
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NewsTwo types of polymicrobial infections in chronic lung diseases
Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. The study was published in the journal ...
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NewsResearchers to study links between Great Lakes algal blooms and human health
University of North Carolina at Chapel Hill researcher Hans W. Paerl will join researchers at the University of Michigan for a $6.5 million, five-year federal grant to host a center for studying links between climate change, harmful algal blooms and human health. Source: Aerial Associates Photography, Inc. by ...
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NewsU-M lands $6.5 million center to study links between Great Lakes algal blooms, human health
Great Lakes researchers at the University of Michigan have been awarded a $6.5 million, five-year federal grant to host a center for the study of links between climate change, harmful algal blooms and human health.
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NewsCommonly used antibiotic brings more complications, death in the sickest patients
Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure for patients with sepsis, a new study finds.
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NewsHow E. coli get a foothold to cause urinary tract infections
New research examines how the bacteria Escherichia coli—responsible for most UTIs—is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.
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NewsRise seen in use of antibiotics for conditions they can’t treat – including COVID-19
A five-year trend study shows a rebound in inappropriate use after an early-pandemic dip, and a need to tackle overuse in all patients during viral illness outbreaks.
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NewsStudy reveals possible triggers for inflammatory bowel disease
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
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NewsTeardrops target multiple COVID variants through the twist in the spike protein
Particles that gum up the keys that the virus uses to enter cells could one day be an effective COVID treatment whenever vaccines and other treatments fall short.
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NewsResearchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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NewsBacteria in the mouth linked to pulmonary fibrosis survival
Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), a new study finds.
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NewsSickle cell raises COVID-19 risk, but vaccination lags
Adults with sickle cell disease around half as likely to have had initial doses as people without sickle cell disease, a study in Michigan shows.
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NewsResearchers identify why cancer immunotherapy can cause colitis
Studies in mice reveal the mechanism that induces this severe side effect and point to a solution that kills the cancer without causing gastrointestinal issues.
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NewsStudy reveals what smoking does to oral bacteria
The father of biotechnologist Giacomo Antonello, a dentist, sometimes amazed patients with his seemingly clairvoyant diagnostic abilities: one look in their mouth and he would advise them to see a specialist, because, he explained, they might have a problem with their heart or diabetes. He often turned out to ...
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NewsSpread of AMR bacteria linked to patient hand contamination and antibiotic use in nursing homes
Nursing home residents have an increasing diversity in the level of care required and this has coincided with an increase in the spread of drug resistant bacteria within these settings.
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NewsPotato supplement modifies gut microbiome, with implications for bone marrow transplants
Researchers at Baylor College of Medicine and the University of Michigan conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients. The study, which appears in the journal Nature ...
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NewsBarnacle-like sticky protein suggests ocean origin for Candida auris
Candida auris is unlike any other known fungus in that it employs a type of protein, called an adhesin, that acts very similar to those used by oceanic organisms, such as barnacles and mollusks.
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NewsLeading scientists issue ‘gain of function’ recommendations
A workshop of leading scientists has reviewed the benefits and risks of ’gain of function’ research, and proposed a foundation to guide discussions and improve oversight moving forward.
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NewsNew insight into how bacteria surf cargo through the cell before division
Researchers have found some bacteria ship cellular cargo by ‘surfing’ along proteins called ParA/MinD ATPases.
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NewsWorkings of bacterial RNA riboswitch laid bare
Researchers have revealed, using a combination of biochemistry, structural biology and computational modeling, how a particular riboswitch regulates its own synthesis, offering a new target for antibiotics.
