All University of Hong Kong articles
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Sludge sequencing reveals novel species and genetic diversity
A study sequencing activated sludge has unearthed a plethora of antibiotic resistance genes and has pointed to the existence of previously unknown microbial species.
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Scientists ID novel host factors that facilitates SARS-CoV-2 entry
Researchers have identified new host factors that interact with the receptor binding domain of the SARS-CoV-2 spike protein to promote viral entry.
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Study shows N95 masks near-perfect at blocking escape of airborne COVID-19
In a head-to-head comparison of masks worn by people with active COVID-19, the inexpensive ‘duckbill’ N95 came out on top, stopping 98% of COVID-19 particles in the breath of infected people from escaping into the air.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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PD-1-enhanced DNA vaccine achieves 6-year cART-free AIDS prevention and virologic control
Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model.
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New institute to bolster global preparedness for future pandemics
The University of Hong Kong (HKU), the University of Cambridge (UCAM), and the International Vaccine Institute (IVI) have established the international headquarters of The Hong Kong Jockey Club Global Health Institute at HKU.
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Scientists find genes in gut microbes that help to alleviate constipation
Researchers have found that probiotic Bifidobacteria longum strains possessing the abfA cluster of genes can ameliorate constipation through enhanced utilization of an indigestible fiber called arabinan in the gut.
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New antibiotic drug approved for clinical trials in humans
A new antibiotic drug has recently gained approval from the authorities to undergo clinical trials.
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Scientists pioneer dual trojan horse approach to combat superbugs
In the relentless battle against antibiotic-resistant superbugs, science continues to unveil ingenious strategies to address their vulnerability. Like other bacteria, superbugs have a unique weakness – their dependence on iron for growth and survival. Iron serves as an essential nutrient that bacteria utilise for various cellular processes, including DNA replication, ...
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Microbiologist and virologist creating Global Pandemic Research Alliance
Columbia University virologist Professor David Ho and The University of Hong Kong (HKU) microbiologist Professor Kwok-yung Yuen are teaming up to create a global alliance for conducting research in emerging infectious diseases.
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Microneedle array with antibacterial nanoparticles targets acne
Researchers have designed a new microneedle patch engineered with ultrasound-responsive zinc-based metal-organic framework (MOF) antibacterial nanoparticles, promising pain-free delivery to treat bacterial infection on skin tissue and facilitate skin repair.
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Global prevalence of H. pylori infection declining
Researchers have found that Helicobacter pylori (H. pylori) infection around the world has been steadily declining over the past four decades, and that the use of antibiotics against it could alter the micro-organisms and the virus community present in the gut.
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First human respiratory organoid culture system reveals secret of Omicron’s transmissibility
Researchers have established the first human respiratory organoid culture system and unveiled a novel mechanism for the high transmissibility of SARS-CoV-2 Omicron variant.
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Novel 2D ultrasound-responsive antibacterial nano-sheets tackle MRSA bone tissue infection
A research team has invented a non-invasive and non-antibiotics technology to effectively reduce methicillin-resistant Staphylococcus aureus (MRSA) infection in bony tissue.
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Researchers create ‘undercover agent’ tool to track bacterial assassins in real time
Researchers have developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells and which can be used to investigate bacterial interactions with the host in real-time during an infection.
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Corals may punish cheating symbiont algae by cutting off their food supply
Corals may ‘punish’ the algae that live inside them by cutting off their food supply if such algae become selfish and renege on their part of the resource-sharing deal with the coral as part of their symbiosis.