All UK & Rest of Europe articles – Page 44
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News
Research uncovers a new path to drug diversity
By exploring protein evolution, scientists have found new “fusion sites” that enable faster and more targeted drug development.
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For each 10% increase of certain bacteria type in the gut microbiome, the risk of hospitalisation for infections falls by up to a quarter
A study of two large European patient cohorts has found that for every 10% increase in butyrate-producing bacteria in a patient’s gut, the risk of hospitalisation for any infection falls by between 14 and 25% across two large national cohorts. The
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Signs of life potentially detectable in single ice grain emitted from extraterrestrial moons
A new lab-based study shows that individual ice grains ejected from the moons of Saturn and Jupiter may potentially contain enough material for instruments headed there in the fall to detect signs of life, if such life exists.
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Climate change disrupts vital ecosystems in the Alps
Reduced snow cover and shifting vegetation patterns in the Alps, both driven by climate change, are having major combined impacts on biodiversity and functioning of ecosystems in the high mountains, according to new research published today.
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Membrane-producing enzyme offers promising target
The enzyme LpxC, which catalyzes the first irreversible step in the biosynthesis of the outer membrane of Gram-negative bacteria, is a highly promising target for the development of antibiotics.
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Careers
Life-changing and unforgettable: Dami and Jisa report back on ABRCMS
Students Dami Okeyoyin and Jisa Salim report back after attending the Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS) 2023 in Phoenix, Arizona in November with AMI trustee Dr Emmanuel Adukwu.
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Protein found in human sweat may protect against Lyme disease
Researchers also found that a variant of the protein is not as protective against the bacterium and increases susceptibility to the disease.
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Scientists create 3D image of the symbiotic communities around plant roots
Researchers report that microbial community composition varies along the root and that this is influenced by the root spatial metabolism.
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Study reveals impact of malaria interventions through routine sampling of pregnant women
Genomic analysis of the malaria parasite in pregnant women attending their first antenatal visit revealed reduced diversity in areas of southern Mozambique where elimination interventions were implemented.
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HIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology
New research demonstrates transport of new-gene editing technology to ‘cut out’ HIV DNA from infected cells; preliminary findings are “very encouraging”, but much work is needed to transform the technology into a cure for HIV.
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Antibiotics combat the gut bacteria that contribute to the pathogenesis of COVID-19
New research indicates that antibiotics can effectively target bacteria in the gut that harbor the virus that causes COVID-19 and produce toxin-like peptides that contribute to COVID-19-related symptoms. In the study, which involved 211 participants and was published in the Journal of Medical Virology, individuals who received ...
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Study reveals how hydrogen supplied energy at life’s origin
A new report uncovers how hydrogen gas provided energy in the past, at the origin of life 4 billion years ago.
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Protein fragments ID two new “extremophile” microbes—and may help find alien life
Scientists used proteotyping to identify two potentially new types of extremophile bacteria. These results suggest proteotyping could be a more complete solution for identifying extremophile microorganisms from small biological samples.
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Warning signs herald the development of antibiotic resistance
A new study shows how heteroresistance, a transient resistance common in many bacteria, can act as a precursor to the development of antibiotic resistance.
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Even inactive smokers are densely colonized by microbial communities
Even inactive smokers are important locations for microbial activity and the production of organic carbon on the sea floor, reveals a study investigating what happens to biotic communities at hydrothermal vents when the source of hot fluids is lost.
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Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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Age and sex associated with patient’s likelihood of antimicrobial resistance
A person’s age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study.
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Revolutionary chronic wound treatment could help millions
A team of scientists has developed an effective treatment for preventing infection in chronic wounds involving the plasma (electrical gas) activation of hydrogel dressings to produce a unique mix of different chemical oxidants.
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Steroid drugs used for HRT can combat E. coli and MRSA
New research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.