Healthy land
Land has a wide variety of uses: agricultural, residential, industrial, and recreational. Microbes play a key role in the terrestrial ecosystem, providing symbiotic relationships with plants. Human use of land has led to the exhaustion of nutrients in soils, contamination of land, and a reduction in biodiversity. Applying our knowledge of microbes will be essential in restoring the biodiversity of affected ecosystems. Greater research into how microbes impact human life on land could all have a positive impact, by increasing crop production, repurposing areas of land and improving microbial biodiversity in soil, land, and water.
News
Biologist Dr. Toby Kiers wins Tyler Prize, calls fungi key to restoring degraded land and an untapped ally for the earth
Evolutionary biologist Dr. Toby Kiers, a world-renowned expert on mycorrhizal networks, is being awarded the Tyler Prize for Environmental Achievement for her “transformative” work, the Tyler Prize Executive Committee announced today.
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NewsScientists reprogramme E. coli to transform sugars into eco-friendly surfactant
A new study demonstrates a sustainable microbial strategy for producing lauryl glucoside by engineering a non-natural biosynthetic pathway in Escherichia coli, revealing precursor availability as a key bottleneck and moving towards greener biomanufacturing.
NewsBrewing a rare medicine: yeast engineered to produce a valuable astragalus isoflavonoid
By reconstructing the complete biosynthetic pathway inside Saccharomyces cerevisiae and systematically removing metabolic bottlenecks, researchers created the first yeast platform capable of producing calycosin-7-glucoside from simple carbon sources.
NewsReconstructing nature’s oxindole factory: yeast-based biosynthesis of medicinal indole alkaloids
By identifying four key enzymes from a North American plant and reconstituting them in yeast, scientists have achieved complete de novo biosynthesis of complex oxindole molecules that are difficult to obtain from plants or chemical synthesis.
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News
Engineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
NewsEngineering yeast to make rare anticancer saponins: reconstructing the complete biosynthesis of polyphyllin II
By combining plant transcriptomics, enzyme engineering, and synthetic biology, a new study demonstrates, for the first time, the full heterologous production of polyphyllin II in Saccharomyces cerevisiae.
NewsScientists develop new biosynthetic route to optically pure S-2-Hydroxyisovalerate
By uncovering an unexpected enzyme activity and combining it with precise metabolic engineering, scientists has transformed Escherichia coli into a microbial factory capable of producing gram-per-liter levels of optically pure S-HIV from renewable carbon sources.
NewsDeadly to amphibians, a fungal strain emerged in Brazil and spread around the world
The fungal infection Batrachochytrium dendrobatidis is responsible for the decline of toad and frog populations across the globe. A new study has pinpointed the origin of the fungal strain.
NewsBat virome evolution reveals cross-species origins of porcine epidemic diarrhea virus and regional surveillance gaps
A study has unveiled the Indochina Peninsula’s bat virome diversity, offering key insights into the origins of porcine epidemic diarrhea virus (PEDV) and critical surveillance priorities.
NewsPlant discovery could lead to new ways of producing medicines
Scientists studying a plant called Flueggea suffruticosa, which produces a particularly powerful alkaloid known as securinine, investigated how this chemical is made - and discovered that the process is driven by a gene that looks more like it comes from bacteria than from a plant.
NewsAboard the International Space Station, viruses and bacteria show atypical interplay
In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless “microgravity” conditions aboard the International Space Station, but the dynamics of virus-bacteria interactions differed from those observed on Earth.
NewsScientists observe infections by cancer-causing retroviruses in koalas as they occur
Scientists analysed the ongoing colonization by two retroviruses of the germline of koalas and resulting deaths from cancer in multi-generational pedigrees of over 100 koalas in US and European zoos. They calculated genetic risk scores (GRS) that can help guide koala breeding programs.
NewsBirding enthusiasts can help songbirds avoid salmonella epidemics
Biologists are developing a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations so that people can protect their feathered friends by taking down bird feeders at the right time.
NewsRare microbial wrinkle structures - signs of ancient life - turn up in an unexpected place
Deep water sediment layers in the Dadès Valley in the Central High Atlas Mountains of Morocco have revealed rare microbial wrinkle structures formed far from sunlight.
NewsVaccine against foot-and-mouth disease could deliver $1.3 billion a year in global livestock benefits
A new foot-and-mouth disease vaccine is projected to deliver over $1.3 billion in annual benefits and transform global livestock resilience.
NewsCat disease challenges what scientists thought about coronaviruses
Researchers have uncovered new details about how a once-deadly coronavirus disease in cats spreads through the immune system. For years, the prevailing belief was that the virus behind feline infectious peritonitis infected just one type of immune cell.
NewsGamma rays quickly toughen nitrogen‑fixing bacteria
Heat‑resilient biofertilizers could help crops cope with rising temperatures but engineering them has been slow and uncertain. A new study shows that pairing experimental evolution with controlled gamma‑ray mutagenesis can accelerate the path to heat‑tolerant nitrogen‑fixing bacteria.
NewsNew study reveals evolutionary and domestication history of button mushroom
A large-scale population genomic study has shed new light on the evolutionary and domestication history of the button mushroom (Agaricus bisporus), one of the most widely cultivated edible fungi in the world.
NewsFrom palm oil to designer enzymes: researchers reprogram yeast cells
Many everyday products contain fatty acids from palm oil or coconut oil, but the extraction of these raw materials is associated with massive environmental issues. Researchers have now developed a biotechnological approach that could enable a more environmentally friendly production method.
NewsNew study finds higher hantavirus risk in drier, underdeveloped areas
In a recent study of the contiguous USA, researchers found that the risk of disease from hantavirus is higher in drier, underdeveloped geographic areas with more socioeconomic vulnerability and increased numbers of unique rodent species.
NewsScientists decode tree genome to unlock terpenoid-based disease resistance
Researchers reported a chromosome-scale genome and multi-omics analysis of a Lauraceae medicinal tree. The study reveals how specific terpene synthase (TPS) genes contribute to antimicrobial compound production and enhanced resistance to plant diseases.
NewsEarthworms turn manure into a powerful tool against antibiotic resistance
Earthworms could become unexpected allies in the global fight against antibiotic resistance, by helping farmers turn manure into safer, high-value organic fertilizer through vermicomposting. Researchers report it can remove antibiotic resistance genes far more consistently than conventional composting.
NewsTraditional herb offers new hope for antibiotic-free pig farming
A new review highlights that Houttuynia cordata extract could serve as a multifunctional natural substitute for antibiotics in swine production. Plant-derived flavonoids, volatile oils, and polysaccharides suppress pathogens including Salmonella, PRRSV, and Streptococcus suis.