All The Sex Issue articles
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News
Gut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
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Potential first new antibiotic for gonorrhoea since the 1990s is effective and safe, finds trial
Gepotidacin could be a new treatment to treat gonorrhoea, protecting against the threat of treatment-resistant gonorrhoea and improving patient treatment experiences, suggests the results of a phase 3 randomised control trial.
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Parasitic infection and treatment linked to cancer-related gene activity in the cervix
New research has revealed that Schistosoma haematobium, a parasitic infection affecting millions globally, can trigger cancer-related gene activity in the cervical lining, with changes becoming even more pronounced after treatment.
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New antibiotic for multidrug resistant superbug triggers suicide mechanism
Researchers have discovered a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhoea.
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FAU secures $1.3 million NIH grant for breakthrough in HIV self-test technology
To address the urgent need for a reliable, rapid and affordable self-test for early HIV detection, researchers have been awarded phase-II of a five-year, $1.3 million grant which will support the development of an innovative disposable microchip technology designed for HIV-1 self-testing during the first two weeks post-infection.
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Researchers develop new DNA test for personalized treatment of bacterial vaginosis
Researchers have developed a simple DNA PCR-based lab test — built on a more detailed genetic analysis of the main group of bacterial organisms that cause bacterial vaginosis — to help clinicians prescribe the right medicine for each patient.
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Probe into human cervical stem cells shows lactic acid bacteria can prevent cervical cancer
Researchers have revealed the identity and differentiation process of human cervical stem cells in a world first study. The results showed that lactic acid bacteria can inhibit the development of cervical cancer.
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Study yields new data on Mpox vaccine effectiveness in people with HIV
A new study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, especially people with HIV, should receive the second dose of the vaccine as recommended.
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Novel insights into Candida glabrata in pregnant women’s reproductive tracts in Hainan
A study of Candida glabrata in pregnant women with vaginal discomfort at Haikou Maternal and Child Health Hospital found that 64.5% of the 594 yeast isolates (383 isolates) showed resistance (R) or intermediate (I) phenotypes to at least one of four commonly used antifungals.
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Features
Urinary tract infections: addressing the gender gap and advancing microbial insights
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, disproportionately affecting women and contributing to a significant healthcare burden.
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Isolated population of chlamydia-free koalas even more vulnerable to the disease
Koalas in south-western Sydney are among the very few in New South Wales (NSW) still free of chlamydia, yet a new study shows they are less likely to adapt to the disease should it arrive on their doorstep.
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A new test will make it possible to detect the parasite responsible for trichomoniasis more quickly and inexpensively
A sensitive, cheap and rapid test is developed to detect the parasite, Trichomonas vaginalis, which causes one of the world’s most common sexually transmitted infections, using an innovative approach that targets highly specific molecules with short nucleic acid sequences.
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New 3D imaging approach reveals intricate steps of virus assembly
A new integrated 3D imaging approach combines cryo-light microscopy and cryo-soft X-ray tomography to reveal the intricate ultrastructure of herpes simplex virus-1 (HSV-1) assembly.
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Lactobacillus-dominated uterus significantly boosts pregnancy outcomes
Researchers analyzed recent studies on the reproductive microbiome and its effects on fertility. They found that a Lactobacillus-dominated (LD) uterine environment significantly improves pregnancy outcomes. Similarly, pregnancy success rates were higher in LD environments.
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Features
The shifting landscape of the cervicovaginal microbiome in chlamydia infection
Bacterial vaginosis (BV) is a remarkably common condition among women of reproductive age, affecting as many as a third of all women at any given time. Yet it remains surprisingly elusive.
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New therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Using population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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New method ‘fishes’ for bacterial STI DNA, revealing how Chlamydia spreads and adapts
Scientists have developed a cutting-edge “target enrichment” technology for bacterial STIs. Using specially designed molecular probes, they “fished” for bacterial STI DNA from clinical samples, enabling high-resolution genome analysis.
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After sexual intercourse, both partners leave traces of their own unique genital microbiome
Researchers have shown that bacterial species are transferred between both individuals during sexual intercourse, and these species can be traced to a sexual partner’s unique genital microbiome, with potential for identifying perpetrators of sexual assault.