All SARS-CoV-2 articles – Page 6
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Intranasal COVID-19 vaccine headed to clinical trials
CyanVac will sponsor a randomized, double-blind Phase 2b study to compare the efficacy and safety of CVXGA, its intranasal vaccine candidate designed to protect against COVID-19, against an FDA-approved mRNA-based COVID-19 vaccine.
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New study helps explain how elderly individuals react differently to COVID-19 than young people
A new study suggests that a suppressed immune landscape is a key driver of age-associated endothelial dysfunction during COVID-19.
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Feeling rough after your COVID shot? That means it’s working!
Side effects of the Covid vaccine may include tiredness, muscle and joint pain, chills, headache, fever or nausea, but a new study finds that the symptoms indicate a robust immune response that is likely to lessen the chances of infection.
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Study finds no association between COVID-19 vaccines and stillbirths
In a new study funded by the U.S. Centers for Disease Control and Prevention, researchers found “no association between COVID-19 vaccination and stillbirth”.
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Virus that causes COVID-19 can remain in sperm for 110 days after infection
Researchers detected SARS-CoV-2 in male reproductive cells under the microscope even when PCR testing failed to detect the virus in semen. The discovery serves as a warning of possible implications for natural conception and assisted reproduction.
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Vaccine approach offers promise to induce longer-lasting protective immunity against COVID-19
A scientific team has engineered a COVID-19 vaccine that induced – in pre-clinical models – very long-lasting, protective immunity against SARS-CoV-2 virus with a single-shot immunisation.
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Oral nucleoside antiviral is progressing toward future pandemic preparedness
Oral obeldesivir has been shown to reduce disease severity in mice infected with one of several different coronaviruses, including SARS-CoV-2 (which causes COVID-19), SARS-CoV and MERS-CoV.
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Pathway into cell influences the outcome of SARS-CoV-2 infection
The protein TMPRSS2 acts as a helper to bring the virus into the cell via the receptor ACE2. This TMPRSS2-mediated uptake significantly alters the immune response of the host cells and drives the evolution of the virus, a new study shows.
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Scientists develop new nanoscale way to see viruses in action
A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, scientists report.
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Statisticians call for rigour and transparency in the evaluation of diagnostic tests
Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published - intended to help prevent future scenarios in which IVDs are marketed widely, but later attract serious concerns about the standards applied to their evaluation.
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Knowledge is a factor in closing black-white COVID-19 vaccination gap
Early in the Covid-19 pandemic, Black Americans were more hesitant to take the Covid-19 vaccine than were White Americans. As the pandemic went on, however, the disparity in vaccination rates between Black and White adults declined. Source: Baltimore County Government People queueing to be vaccinated, 23 December 2020 ...
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New electrostatic sampler boosts indoor virus detection speed
Researchers have developed a groundbreaking electrostatic air sampler that enhances the rapid monitoring of airborne influenza and coronavirus.
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Study shows N95 masks near-perfect at blocking escape of airborne COVID-19
In a head-to-head comparison of masks worn by people with active COVID-19, the inexpensive ‘duckbill’ N95 came out on top, stopping 98% of COVID-19 particles in the breath of infected people from escaping into the air.
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Effectiveness of updated COVID-19 vaccines wanes moderately over time, is lower against currently circulating variants
New research shows boosters targeting omicron subvariants of SARS-CoV-2 are still providing reasonably durable protection against infection, hospitalization and death from COVID-19, but are less protective against the JN.1 strain.
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Researchers take step toward development of universal COVID-19 antibodies
Scientists have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.
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Risk of death from COVID-19 lessens, but infection still can cause issues 3 years later
A new study also shows that patients hospitalized within 30 days after infection face a 29% higher death risk in the third year compared with those not infected.
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Scientists probe missing microbes in infants and children in the COVID-19 pandemic
Researchers conducted a comparative analysis of the gut microbiome of 1,126 children and infants during the COVID-19 pandemic in the Beijing area, revealing the variation of their gut microbiome.
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Century-old vaccine protects type 1 diabetics from infectious diseases
Research shows that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
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How vaccine messaging is framed makes a difference, new research reveals
A one-size-fits-all approach to communicating the benefits of vaccines isn’t effective. Message framing plays a crucial role depending on the mindset, so it requires communicating in different ways for different people, a new study says.
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Long-term protection from SARS-CoV-2 variants in mice by a Phase II clinically evaluated original mRNA vaccine booster
A new study discusses the development of an mRNA vaccine (LVRNA009) that encoded the S protein of the Wuhan-Hu-1 strain and evaluated the long-term protection potential against SARS-CoV-2 variants.