All SARS-CoV-2 articles – Page 17
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Molnupiravir dose of human effect size-equivalent blocks Covid transmission in ferrets
Two oral drugs provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose.
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Modulating type 1 Interferon may expand treatment options for COVID-19
Researchers have, for the first time in nonhuman primates, studied how modulating the signaling of type 1 Interferon (IFN-I), one of the body’s initial defenses against infection, impacts SARS-CoV-2 viral replication and disease progression.
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New Drosophila toolkit to help reveal how Covid-19 virus impacts human health
Researchers have developed a toolkit of <i>Drosophila melanogaster</i> COVID-19 resources to study how viral and human proteins interact, with the goal of developing therapies for symptoms caused by existing and new strains.
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Moderna is safest, most effective mRNA vaccine against COVID-19 for older adults
A study of older US adults found that the risk of negative effects of both mRNA vaccines is exceptionally low, but lowest with the Moderna vaccine.
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AI-based wastewater sampling predicts COVID hospital admissions
Researchers have developed an accurate prediction tool for estimating COVID-19 hospital admissions, using an Artificial Intelligence (AI) based system with wastewater sampling.
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Breath test rapidly detects COVID-19 virus
Scientists have developed a breath test that quickly identifies those who are infected with the virus that causes COVID-19. The device requires only one or two breaths and provides results in less than a minute.
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COVID-19 vaccination reduces severity and mortality after breakthrough infections
Among individuals recently infected with SARS-CoV-2, those who were fully vaccinated had lower concentrations of almost all inflammation markers (cytokines and chemokines) than those who were unvaccinated in the short-term and long-term after symptomatic SARS-CoV-2 infection.
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Newly discovered antibodies can neutralize COVID-19 variants
Scientists have isolated potent neutralizing antibodies from a COVID-19 vaccinated SARS survivor that exhibited remarkable breadth against known sarbecoviruses.
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Smaller magnetic beads with superior magnetic moment capture Covid virus more quickly
Scientists have developed a more efficient way to test SARS-CoV-2 Virus with a novel nano-immune magnetic bead (Mal-IMB) that can efficiently be bound to the pseudovirus in the study of protein biomimetic mineralization and synthesized into magnetic nanoparticles.
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Far UVC light could have disinfection potential against Covid variants
Scientists have investigated the inactivation efficacy of different UV wavelengths and assessed the safety profile for effective management of COVID-19 risks.
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Spike protein mutants with low binding affinity usher in new Covid vaccine
Researchers have succeeded in producing a new vaccine against the SARS-CoV-2 coronavirus by identifying spike protein mutants that lack binding affinity.
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Interferon could help reduce the spread of COVID-19
Results of an innovative clinical trial have shown that the drug interferon could help reduce the spread of COVID-19 from a positive person to their household contacts, with the study helping to inform treatment options for a future pandemic.
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Fly toolkit created for investigating COVID-19 infection mechanisms
A new ‘fly-to-bedside’ resource offers a shortcut for developing drug therapies needed for long COVID and future coronavirus outbreaks.
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Scent dogs can detect COVID-19 more rapidly and accurately than current tests
Scent dogs may represent a cheaper, faster and more effective way to detect COVID-19, and could be a key tool in future pandemics, a new review of recent research suggests.
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Omicron subvariant BA.5 efficiently infects lung cells
Over the course of evolution of Omicron subvariants, viruses may arise that regain the ability to effectively spread in the lung and cause severe illness in risk patients and people with insufficient immunity, a new study suggests.
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High-res map of the human placenta reveals COVID virus hideouts
Researchers have developed a high-resolution map of the human placenta visualizing an array of different immune microenvironments in healthy placentas from uninfected pregnancies, and those from pregnancies affected by COVID infections.
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Purecap technique opens doors to more effective mRNA vaccines
Researchers have developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.
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Frequent use of antibiotics linked to severe Covid outcomes
Frequent and diverse use of antibiotics may be associated with developing more severe outcomes after a COVID-19 infection, including death, a new study has shown.
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Scientists develop all-species Covid test
In an advance that will help scientists track coronavirus variants in wild and domesticated animals, researchers report they can now detect exposure to the SARS-CoV-2 virus in any animal species.
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COVID-19 jab reduced disease disparities between low- and high-income communities
COVID-19 vaccination helped reduce disparities in disease incidence between low- and high-income communities, according to a new analysis led by Cedars-Sinai investigators.