All SARS-CoV-2 articles – Page 15
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Model can predict the evolution of new COVID variants
An international research team has developed a model that predicts the likely evolution of variants of the SARS-CoV-2 virus.
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Gut fungi trigger long-lasting severe COVID-19 immune response
Researchers have found that the growth of fungi in the intestinal tract, particularly strains of Candida albicans yeast, trigger an upsurge in immune cells whose actions can exacerbate lung damage.
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Broad-spectrum antiviral candidate targets dengue and SARS-CoV-2
A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.
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Germicidal UV lights could be producing indoor air pollutants, study finds
While useful for killing pathogens including SARS-CoV-2, the lights may cause unwanted chemical reactions and should be used with ventilation, researchers say.
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Alert immune system in respiratory tract protects children from severe Covid
Scientists have discovered that the immune system in the upper respiratory tract is much more alert and active in children before infection than in adults and is therefore better equipped to fight the virus.
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Study finds increased risk of Guillain-Barré after COVID-19 infection
Having a COVID-19 infection is associated with an increased risk of developing the rare disorder called Guillain-Barré syndrome within the next six weeks.
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Single vaccine protects against three deadly strains of coronavirus
A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies.
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Viral persistence and serotonin reduction can cause long COVID symptoms
Components of the SARS-CoV-2 virus remain in the gut of some long COVID patients, causing persistent inflammation, vagus nerve dysfunction, and neurological symptoms.
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Targeting a coronavirus ion channel could yield new Covid-19 drugs
Chemists discover the structures of open and closed states of the channel, which could help the development of antiviral drugs to reduce inflammation.
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Study reveals how young children’s immune systems tame SARS-CoV-2
A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.
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AI tool can help forecast viral outbreaks
A new AI tool called EVEscape uses evolutionary and biological information to predict how a virus could change to escape the immune syste, and successfully predicted the most concerning new variants that occurred during the COVID-19 pandemic.
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New UK projects to kickstart future vaccine development awarded £25m
Three UK projects designed to build our understanding of viruses and how the immune system reacts to different challenges will share £25m in new funding from UKRI.
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Vulnerability to different COVID-19 mutations depends on previous infections and vaccination
A person’s immune response to variants of SARS-CoV-2 depends on their previous exposure – and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection.
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Covid-19 protein primes RNA synthesis in human cells
Researchers have shown for the first time that it is the human protein SND1 which works together with the viral protein NSP9 to stimulate the SARS-CoV-2 virus’s genetic replication program in infected cells.
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Sugar binding to spike protein is key to coronavirus cell entry
A study uses powerful microscopes and computer simulations to reveal how a tiny sugar molecule binds to a human coronavirus spike and triggers exposure of components that are required to invade the host cell.
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Portable laboratory devices can detect SARS-CoV-2
A new study has demonstrated rapid and sensitive on-site detection of SARS-CoV-2 RNA from environmental surfaces using a portable laboratory device.
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Scientists discover alternative base modification for mRNA therapeutics
Researchers have incorporated a newly discovered base, called base Z, into mRNA to create Z-mRNA that has improved translational capacity, decreased cytotoxicity and drastically reduced immunogenicity compared to unmodified mRNA.
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Does COVID-19 or COVID-19 vaccination worsen migraines?
New research indicates that COVID-19 and COVID-19 vaccination have negligible effects on migraine severity.
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Nobel Prize goes to researchers whose discoveries paved way for mRNA vaccines
The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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Covid-linked sepsis more common and deadly than previously thought
New research suggests that the virus responsible for COVID-19 was a more common and deadly cause of sepsis during the initial period of the pandemic than previously assumed.