All SARS-CoV-2 articles
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Seemingly ‘broken’ genes in coronaviruses may be essential for viral survival
Some coronaviruses, including Covid-19 have extra ‘accessory’ genes in addition to the usual minimal viral set and researchers have found that some of these viral genes have stuck around even though they don’t produce a working protein.
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Global antibiotic consumption has increased by more than 21 percent since 2016
An analysis of antibiotic sales data from 67 countries from 2016-2023 shows a decrease in consumption in high-income countries countered by an increase in middle-income countries.
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A joint consensus report published on SARS-CoV-2 genomic surveillance for hospitals and public health laboratories
A joint consensus report that reviews and summarizes standard concepts and best practices for next-generation sequencing methods for SARS-CoV-2 genomic surveillance.
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New therapeutic approach for severe COVID-19
A new clinical study shows that an inhibitor of Fas ligand, also called CD95 ligand, led to a faster recovery of COVID-19 patients and reduced mortality.
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Studies point to correlation between preeclampsia and COVID-19 in pregnant women
A review article by researchers discusses relationships between these two conditions, identifying biomarkers that can help clinicians make a differential diagnosis.
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Scientists develop new SARS-CoV-2 variant detection method
Researchers have made a significant breakthrough in the fight against COVID-19 with the development of Intelli-OVI, a cutting-edge diagnostic tool capable of rapidly identifying emerging variants of the SARS-CoV-2 virus.
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SARS-CoV-2 ‘steals’ our proteins to protect itself from the immune system
Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly impairs viral clearance which may affect the course of ...
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Acquired immune thrombotic thrombocytopenic purpura (TTP) associated with inactivated COVID-19 vaccine CoronaVac
A new study presents two cases of immune thrombotic thrombocytopenic purpura occurring after the administration of the inactivated vaccine CoronaVac from Sinovac Biotech, highlighting the potential association between this type of vaccine and TTP.
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Nanoparticles designed to trap and neutralise large amounts of SARS-CoV2
Researchers have developed a new class of nanostructures capable of trapping and neutralising large quantities of the SARS-CoV2 virus particles, both in liquid solutions and on the surface of materials.
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Scientists assess efficacy of clinical drugs targeting SARS-CoV-2 main protease
A critical player in the virus’s life cycle is the main protease (Mpro), also known as NSP5 or 3CL protease, which plays a crucial role in the cleavage and maturation of SARS-CoV-2 proteins within the host cells.
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Study reveals stubborn mistrust in COVID-19 vaccine science
A new study sheds light on public trust in COVID-19 vaccine science and its impact on vaccine acceptance in the United States from 2021 to 2023, finding that around one-third of respondents expressed mistrust in the science behind COVID-19 vaccines.
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Repeated COVID vaccines enhance mucosal immunity against the virus
New work has found that repeated Covid-19 vaccinations lead to the presence of mucosal antibodies, for example, inside the nose.
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Novel antibody platform tackles viral mutations
Scientists have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.
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Floor swabbing could help prevent COVID-19 outbreaks in hospitals
In two Ontario hospitals, high levels of SARS-CoV-2 on floors correlated with COVID-19 cases among healthcare workers and patients, suggesting floor swabbing as a potential method to prevent outbreaks.
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Study uncovers how Covid-19 is so good at defeating the innate immune response
The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell’s innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.
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COVID study reveals virus-induced inflammation during pregnancy, redefines vertical transmission
A protein made by SARS-CoV-2 can pass through the placenta and cause serious inflammatory immune responses in the fetus for 66% of pregnancies.
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Scientists discover series of SARS-CoV-2 mpro inhibitors for potential COVID-19 treatments
New research has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.
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Study finds persistent infection could explain long COVID in some people
Researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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New mouse models offer valuable window into COVID-19 infection
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19 because their cells were engineered to include two important human molecules that are involved in infection of human cells.