All Salmonella Typhimurium articles
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NewsEngineered bacterial therapy activates immune response in cancer preclinical studies
Researchers have developed a new bacterial immunotherapy that delivers immune-activating proteins directly to solid tumors, which can often suppress the immune system. ACTM-838 targets phagocytic immune cells within the tumor microenvironment.
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NewsEngineered gut bacteria improves survival outcomes in colorectal cancer tumors
A genetically modified Salmonella typhimurium strain can colonise tumours and release a therapeutic protein, LIGHT, to induce the formation of mature tertiary lymphoid structures (mTLSs) in laboratory models.
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NewsYeast in gut microbiome can worsen salmonella infection
Researchers have discovered that a yeast commonly found in our gut can make infection with salmonella worse. Salmonella binds to Candida albicans and triggers a chain reaction that allows the bacteria to better invade cells lining the intestines.
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NewsBacterial signaling molecule that choreographs flip between biofilm and motility could transform biotechnology and medical applications
A bacterial signaling molecule involved in flipping the switch between sessile and motile forms could offer huge potential in improving probiotics, boosting wastewater treatment and producing therapeutic compounds.
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NewsBacteriostatic activity and mechanism of minerals containing rubidium
A new paper on traditional Chinese medicine outlines the bacteriostatic activity and mechanism of minerals containing rubidium (MCR).
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NewsNovel breath test shows promise for diagnosing and monitoring bacterial infections
A new, non-invasive breath test has emerged as a potential breakthrough for rapidly diagnosing bacterial infections and tracking treatment effectiveness.
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NewsScientists lift lid on Salmonella dry surface biofilm
Food scientists have revealed key characteristics of the foodborne pathogen Salmonella dry surface biofilm (DSB), a previously overlooked type of biofilm that commonly exists in dry food processing environments.
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NewsAI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, researchers have shown. An algorithm can be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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NewsResearchers discover how a deadly strain of salmonella fine-tunes its infection tactics
A new study investigates how pathogens like salmonella change their disease characteristics under fluid shear conditions like those they encounter in our bodies during infection.
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NewsScientists probe spermidine production to combat emerging drug resistance in Salmonella
Scientists have pinpointed how Salmonella Typhimurium uses a key molecule called spermidine to shield itself from the onslaught of the host’s defence machinery - and an existing FDA-approved drug can reduce spermidine production.