All Rockefeller University articles
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News
Scientists find flawed data in recent study relevant to coronavirus antiviral development
A new study shows why scientists still don’t know how the NiRAN domain works. The findings could have sweeping implications for drug developers already working to design antivirals based on flawed assumptions, and underscore the importance of rigorous validation.
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Researchers find CRISPR is capable of even more than we thought
Researchers studying key immune components of some CRISPR systems have announced the newest CARF effector they’ve discovered, which they coined Cat1 - it can deplete a metabolite essential for cellular function.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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News
A new class of antivirals could help prevent future pandemics
A new study introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, including Ebola and dengue, as well as cytosolic-replicating DNA viruses, including Pox viruses.
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Could a bout of COVID protect you from a severe case of flu?
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one?
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Researchers may have found an Achilles heel for Hepatitis B
Researchers have revealed never-before-seen mechanisms that may lead to new therapeutic approaches for HBV.
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News
Inexpensive way to produce anti-Covid nanobodies cuts down on the llamas
Researchers have come up with a less expensive way to isolate and identify nanobodies that target various parts of the SARS-CoV-2 spike protein and are currently derived from llamas.