All Research News articles – Page 6
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Add some spice: Curcumin helps treat Mycobacterium abscessus
Researchers have found that adding curcumin boosts the efficacy of bedaquiline, an antimycobacterial used to treat tuberculosis, in combating M. abscessus infections. Curcumin is the compound that gives turmeric its characteristic bright orange color.
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Helicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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Current antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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Metagenomic analysis of tick-borne viruses in Inner Mongolia
A new study maps the landscape of TBVs in Inner Mongolia, but also highlights the potential spillover risk of TBVs. These findings underscore the urgent need for One Health strategies for monitoring emerging TBVs at the tick-human-livestock interface in northern China.
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From order to chaos: Understanding the principles behind collective motion in bacteria
A new study has revealed how bacterial swarms transition from organized movement to chaotic flow. Combining large-scale experiments, computer modeling, and mathematical analysis, the team uncovered intermediate states that emerge between order and turbulence.
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Epstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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Genetic resistance factors and antimicrobial resistance phenotypes in methicillin-resistant Staphylococcus aureus isolates of animals and humans
A new study identified three functional protein families in MRSA, through sequencing, that confer extensive antibiotic resistance independent of the known antibiotic resistance determinants, mecA and mecC.
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The key role of soil micro-food web complexity in agricultural productivity
Soils inoculated with micro-food webs have significantly higher levels of total nitrogen (TN), total phosphorus (TP), microbial biomass, and plant nitrogen and phosphorus compared to the control and untreated (unsterilized) soil, a new study shows.
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New method uncovers dynamic microbial community in coastal sediments
Scientists utilises single celll genomics and cell staining approaches to investigate the respiratory rates and metabolic activities of the diverse microbial communities in low biomass aqautic environments, such as Maine’s coastal sediments.
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New CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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Study finds new targets needed for vaccine to prevent herpesvirus transmission to babies
Despite the lack of research on vaccines against congenital cytomegalovirus (CMV), a research has recently discovered that the virus is able to cause cross-placental transmission even with the absence of multple essential proteins, providing insights for future vaccine development.
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Older adults might be more resistant to bird flu infections than children
Previous exposures to seasonal flu strains could prime the immune system to produce antibodies against the current version of H5N1 avian influenza virus in older adults, whilst children would benefit more from H5N1 vaccinations.
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New CRISPRs expand upon the original’s abilities
By scouring through a massive bacterial metagenomic databases, researchers have discovered new CRISPR-Cas systems as efficient as the conventional one. One of the candidate system has found with the technological potential to expand its impact in research, biotechnology and medicine.
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The relationship between gut microbiota, immunoglobulin A, and vaccine efficacy
Researchers concluded that the close relationship between immunoglobulin A (IgA) deficiency and the gut microbiota overgrowth is closely tied with the pneumococcal vaccine effectiveness in adults, thus providing insights for preventative strategies to enhance the vaccine response.
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A study identifies ‘surprising’ cause of sargassum blooms in the Caribbean
A group of interantional researchers identified the cause of sargassum blooms in the tropical Atlantic Ocean using computer modelling. They have modelled the ocean currents, wind pattern and the growth conditions that help them thrive in the region.
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First coronavirus similar to MERS is found in bats in South America
A novel coronavirus, which shares high genetic similarities with MERS-CoV, was identified in bats in the state of Ceará, Brazil. Experiments to find out whether it can infect humans are set to take place in collaboration with Hong Kong University.
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COVID-19 discovery opens door to new treatments for chronic lung problems
A discovery was made to understand how severe viral infections, like COVID-19 and flu could destroy the ability of immune cells to repair the tissue damage in lungs, causing long COVID and other chronic lung diseases.
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Researchers develop method to identify dormant cells that carry HIV
A new method is developed that utilizes a fluorescent genetic switch to tag and trace the lineages of the HIV-infected cells, including the dormant ones. This system might help to develop target therapies for the infected immune cells.
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Symptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.