All Research News articles – Page 4
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Movie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
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Green recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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Bartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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Origin of life: How microbes laid the foundation for complex cells
Researchers examining links between Asgard archaea and eukaryotes have shown that Asgard tubulins form similar microtubules, albeit smaller than those in their eukaryotic relatives. Unlike actin, these tubulin proteins appear in very few species of Asgard archaea.
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Antibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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A high-fat diet may impair response to infection
A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system’s ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses. The study demonstrated that male mice fed a high-fat ...
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New model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.
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Researchers test new, more reliable method to detect chagas disease
Researchers have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide.
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From pollution to polymer: Methane-munching microbe brews biodegradable plastic at high speed
Scientists have tapped into a methane-consuming bacterium, Methylocystis suflitae, to produce biodegradable plastics called polyhydroxyalkanoates (PHAs), offering a dual win for climate and sustainability.
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Nature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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Gatekeeping barriers manage communications between plants and bacteria
For over a century, the Casparian strip has been known as the root’s doorman, controlling what enters the plant. But a new study reveals it has a second job: regulating the delicate metabolic trade between plants and bacteria.
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Four advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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Tuberculosis in children and adolescents: EU/EEA observes a rise in 2023
The notification rate of tuberculosis (TB) went up from 2 to 2.5 per 100,000 population. But overall, numbers of notified paediatric cases remain relatively low across the region.
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Efficacy of topical Nigella sativa L. with vinegar in the treatment of acne vulgaris
A team of researchers in India assessed the efficacy and safety of a topical formulation combining Kalonji and Sirka for the treatment of mild to moderate acne vulgaris. The formulation was compared with a 5% benzoyl peroxide.
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Japanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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Guardians of the vineyard: Canines and chemistry work to combat powdery mildew
Researchers are now analyzing volatile chemicals emanating from grape leaves infected by a fungus called powdery mildew with the goal of improving training for vineyard canines that use their noses to detect infected vines.
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Deadly bacteria developed the ability to produce antimicrobials and wiped-out competitors
A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominant strain.
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H5N1 influenza viral lineages beginning to evade human immunological defenses
A new computer modelling approach predicts the protein-antibody interactions of the potentially pandemic-causing H5N1 avian influenza virus lineage. It helps to understand the viral evolution to ensure high vaccine efficacy.
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Hidden threat: The evolving fungus that spreads through cats and humans
Researchers have developed a better understanding about the molecular basis of the Sporothrix species in virulence and evolution, amid the largest sporotrichosis epidemic in Brazil. The identification of the genetic markers helps to enhance fungal surveillance and strengthen disease control.
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Researchers discover Achilles heel of Lyme disease pathogen
Researchers discovered and investigated an unique enzyme used in the pathway specific to Borrelia burgdorferi, the parasite that causes Lyme disease. The enzyme serves as the ideal genus-specific target for therapeutic intervention.