All Research News articles – Page 3
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Breakthrough as researchers discover new class of antibiotics
Researchers have identified a strong candidate to challenge even some of the most drug-resistant bacteria on the planet: a new molecule called lariocidin.
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Correcting imbalance with the gut microbiota after stroke could reduce brain inflammation
An imbalance in ligands, which are molecules produced by the body and the gut microbiota, can affect a key receptor protein that plays a role in brain inflammation after stroke, according to researchers.
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Antibiotic exposure in infancy may boost Type 1 diabetes risk - but microbiota can help
Exposure to antibiotics during a key developmental window in infancy can stunt the growth of insulin-producing cells and may boost risk of diabetes later in life. But the research pinpoints specific microbes that may help those critical cells proliferate in early life.
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The gut microbiota-metabolites-brain axis mediates social behavior dysfunction following anaesthesia
New research shows that the anaesthetic Sevoflurane (Sev) influences social functioning via the gut-brain axis, with microbiota-derived bile acids serving as critical mediators in this pathway.
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Tadpoles try to flee dangerous virus in their pond by growing much faster than normal
A new study shows that larvae of wood frogs respond to the presence of a deadly ranavirus by growing and maturing precociously. In response to ranavirus, tadpoles change their growth, development, and resource allocation, which may help them tolerate the energetic demands of infection or escape risky environments to avoid infection.
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C. diff uses toxic compound to fuel growth advantage
The pathogen C. diff — the most common cause of health care-associated infectious diarrhea — can use a compound that kills the human gut’s resident microbes to survive and grow, giving it a competitive advantage in the infected gut.
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Growing body of evidence links HPV with heart disease
In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a study.
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Probe into human cervical stem cells shows lactic acid bacteria can prevent cervical cancer
Researchers have revealed the identity and differentiation process of human cervical stem cells in a world first study. The results showed that lactic acid bacteria can inhibit the development of cervical cancer.
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Researchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia
Researchers have achieved the biosynthesis of the antiviral ingredient lignan glycoside in yeast Saccharomyces cerevisiae. By mimicking the spatial and temporal regulation of plant biosynthesis, they designed a system with obligated mutualism, enabling metabolic division of labor among different yeast strains.
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Susceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.
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Newer hepatitis B vaccine shows promise as booster for health care workers
A new study compares the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals.
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Evaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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Biogenic construction: The new era of civil engineering
Inspired by the concept of harmonious coexistence between humans and nature, a new concept, biogenic construction, for civil engineering is proposed in a new paper.
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New study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.
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Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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Breaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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Study evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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Scientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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New study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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Movie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.