All Research News articles – Page 12
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Faulty ‘fight or flight’ response drives deadly C. difficile infections
The portion of our nervous systems responsible for the “fight or flight” response can shape the severity of potentially deadly C. difficile infections.
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Scientists discover how innate immunity envelops bacteria
The human protein GBP1 fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now. Researchers have unravelled how this protein operates.
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Possible trigger of Crohn’s disease discovered: Dysfunctional mitochondria disrupt gut microbiome
Disruptions of mitochondrial functions have an influence on Crohn’s disease, a connection now revealed by researchers who showed that defective mitochondria in mice trigger symptoms of chronic intestinal inflammation and influence the microbiome.
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Researchers identify signs tied to more severe cases of RSV
In a new study, researchers found an increase in NK cells in the airways of children with severe RSV as well as other alterations that suggest these cells may be contributing to disease severity.
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Study identifies potential targets for treatment of visceral leishmaniasis
Discovery of a novel class of proteins that help regulate the parasite’s essential cellular functions could lead to the development of more effective drugs against the disease. More than 3,500 new cases are notified each year in Brazil.
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Selfishness mechanism points way to optimizing inhibitors that fight antibiotic resistance
Resistance can be fought by targeting bacteria that are ’selfish’ with their antibiotic resistance tools, according to a new study.
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Chronic stress accelerates colorectal cancer progression by disrupting balance of gut microbiota
Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.
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Hidden trails of marine snow can affect how the ocean stores carbon
A new study reveals never-before seen mucus ‘parachutes’ produced by microscopic marine organisms that significantly slow their sinking, putting the brakes on a process crucial for removing carbon dioxide from the atmosphere.
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Lachnospiraceae could be key to successful fecal transplants
Fecal microbiota transplants are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why.
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Sludge sequencing reveals novel species and genetic diversity
A study sequencing activated sludge has unearthed a plethora of antibiotic resistance genes and has pointed to the existence of previously unknown microbial species.
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Scientists discover viral trapdoor blocking HIV and herpes
A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them ...
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Fungi recognise shapes and adjust direction of growth
A study suggests that the mycelial network of fungi can communicate information about its surroundings throughout the entire network, and change its direction of growth accordingly based on the shape.
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Researchers uncover unique photosynthetic mechanisms of purple bacteria
Using cutting-edge techniques, investigators have unveiled intricate detailed images of the key photosynthetic protein complexes of purple bacteria. These images shed new light on how these microorganisms harness solar energy.
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Wood-degrading fungal enzymes reprogrammed to biorecycle plastic
Lytic polysaccharide monooxygenases secreted by filamentous fungi break down the surface of cellulose to weaken it and make complete degradation easier, making them perfect candidates for engineering into chimera enzymes for plastic degradation.
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Viral messaging can deliver lessons on how infectious diseases spread
A new study explores a hybrid approach to understanding social networks that involves inferring not just social contacts but also the rules that govern how contagion and information spread.
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Scientists uncover Chlamydia’s sneak attack strategies
Researchers have described the structural and functional methods Chlamydia pneumoniae uses to penetrate the human cell: It mimics molecular structures of the human cell (so-called “molecular mimicry”) and uses them for its attack.
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Next-gen sequencing reveals array of pathogens in longhorned tick
A new study of microbial diversity in the longhorned tick indicates the high relative abundance of both pathogenic bacteria and non-pathogenic endosymbionts and the potential for pathogen transmission to residents of Shaanxi province.
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Zika virus offeres potential as treatment for brain cancer: review
Fourteen studies showed that Zika virus reduced cell viability, inhibited the growth and proliferation of glioma stem cells (GSCs), and decreased Bcl2 expression in central nervous system tumors, potentially enhancing chemotherapy and radiotherapy effects.
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Gut microbiome has central role in human aging
The gut microbiome holds a central role in human aging, influencing everything from metabolic function to immune health, a new review shows.
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More than 160,000 new virus species discovered by AI
161,979 new species of RNA virus have been discovered using a machine learning tool that researchers believe will vastly improve the mapping of life on Earth and could aid in the identification of many millions more viruses yet to be characterised.