All Research News articles – Page 109
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Artificial cells show that ‘life finds a way’
Scientists studying a synthetically constructed minimal cell that has been stripped of all but its essential genes have found it can evolve just as fast as a normal cell.
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Gene expression in apicoplast could be target for malaria treatment
Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum is regulated by melatonin in host blood, and intrinsic parasite cues, via a factor called ApSigma, a recent study reveals.
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Vaginal suppository with lactobacilli can prevent recurrent cystitis
Scientists find that administration of Lactobacilli could mitigate the differences in vaginal microbiota between women with and without recurrent cystitis.
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Frequent use of antibiotics linked to severe Covid outcomes
Frequent and diverse use of antibiotics may be associated with developing more severe outcomes after a COVID-19 infection, including death, a new study has shown.
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Self-produced bacterial toxin induces cancer cells to ‘commit suicide’
Researchers have encoded a toxin produced by bacteria into mRNA (messenger RNA) molecules and delivered these particles directly to cancer cells, causing the cells to produce the toxin – which eventually killed them with a success rate of 50%.
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New bacterial blueprint will help fight antibiotic resistance
Scientists have gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.
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Scientists uncover secrets of bacteria threatening Vidalia onion production
Researchers have confirmed which genes in the bacterial pathogen Pantoea ananatis high virulence cluster are essential and which genes contribute partially to a disease that causes rotting symptoms in Vidalia onions.
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Alarming antibiotic resistance discovered in war-torn Ukraine
Microbiologists investigating bacterial resistance among the war-wounded Ukrainian patients treated in hospitals have warned that the entire European region is under threat after finding that many were affected by bacteria that exhibited an extremely high level of antibiotic resistance.
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Natural molecule added to toothpaste may help prevent plaque and cavities
Scientists have discovered that 3,3′-Diindolylmethane (DIM), a naturally occurring molecule also known as bisindole, reduces the biofilms that produce plaque and cavities by 90% and is also found to have anti-carcinogenic properties.
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New CRISPR gene editing approach opens up more of the genome
Scietnists have come up with a new way to identify diverse CRISPR RNA variants that can specifically home in on challenging areas of DNA to target for editing. The new approach opens up more of the genome for editing, enabling the repair of mutations associated with more diseases.
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Nearly half of TB cases in prisons worldwide go undetected
In the first global assessment of tuberculosis among incarcerated people, a new study found consistently high TB case rates and low case detection in prisons.
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New enzyme designed using Antarctic bacteria and computer calculations
For the first time, researchers have succeeded in predicting how to change the optimum temperature of an enzyme using large computer calculations and based on a cold-adapted enzyme from an Antarctic bacterium.
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Immune-boosting therapy helps honey bees resist deadly viruses
Scientists have successfully tested a novel way of boosting honey bees’ immune systems to help them fend off deadly viruses, which have contributed to the major losses of the critical pollinator globally.
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Future medicines could feature ingredients targeting bacterial motility and chemotaxis
Future medicines will probably be made up of a cocktail of compounds that inhibit different bacterial targets, including some that act against their motility and chemotaxis mechanisms, a new review suggests.
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‘Hospital pathogen’ widespread in Vietnam’s environment
A pathogen considered to be a cause of hospital infection is widespread in Vietnam, turning up in farm soil and pig faeces as well as hospital beds and toilet floor surfaces, with 70% of isolates found to be resistant to at least one class of antimicrobials.
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Cyanotriazole compounds can rapidly cure trypanosome infections in mice
Scientists have identified a class of cyanotriazoles (CTs), which exhibit potent trypanocidal activity and lead to rapid clearance of parasites both in vitro and in mouse models of Chagas disease and human African trypanosomiasis.
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CRISPR-like system in eukaryotes can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
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Nanoparticle may improve mRNA cancer vaccines
Tests in mice with melanoma and colon cancer show the tiny particle creates an ‘army’ of immune cells that carry vaccine’s instructions, say the researchers.
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Flaws in COVID-19 weather studies spark call for improved publishing practices
Research that linked the weather with the spread of COVID-19 during the pandemic was inaccurate and poorly scrutinised by fellow scientists, suggests a new study.
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Molecular insights may inform new treatments for drug-resistant TB
Researchers have used state-of-the-art imaging to examine two new compounds that target ATP synthase, potentially stopping TB bacteria from producing the energy they need to survive.