All Proteomics & Enzymology articles – Page 4
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News
Scientists uncover how coronavirus defends itself against our immune system
A research team identifies “protective switches” in the protein of the SARS-CoV-2 virus.
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Protein may be the ‘glue’ that helps COVID virus stick
A study found that perlecan LG3 – a protein most commonly found in blood vessels and the brain – readily formed a stable bond with the COVID spike protein and perhaps enhanced the virus’ ability to bind with cells.
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Scientists make COVID receptor protein in mouse cells
Initially motivated to make receptor-based sensors and therapies for COVID-19, scientists develop general strategy for producing other complex proteins.
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BioExcel-CV19 offers breakthrough in understanding COVID-19 proteins
Designed to meet the urgent need for insights into the molecular intricacies of SARS-CoV-2 infection, BioExcel-CV19 is a repository for Molecular Dynamics (MD) simulations.
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Researchers uncover how molecular freight elevators work in pathogenic bacteria
Researchers studying bacterial membrane transporters have studied the interaction between the transporter and its soluble substrate binding protein, showing that they adapt precisely to each other during the transportation process.
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Researchers discover molecular ‘barcode’ used by bacteria to secrete toxins
Researchers have discovered a molecular “barcode” system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
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Researchers develop novel solution for Pichia pastoris enzyme production platform
A new study outlines a novel approach in enzyme production, harnessing the untapped potential of cyanobacterial biomass within the P. pastoris platform.
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Scientists reveal rare enzyme role change with bacterial defense system assembly
A never-before-seen phenomenon in a protein: alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
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Study reveals Zika’s shape-shifting machinery—and a possible vulnerability
Zika’s crucial enzyme performs multiple tasks, but a wrench in the system could bring it to a screeching halt.
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Bacteria engineered to biosynthesize intricate protein complexes
Researchers have developed an innovative bioengineering approach using genetically modified bacteria that can incorporate protein cages around protein crystals, producing highly customized protein complexes.
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Reduced activity of key enzyme linked to microcephaly in Zika-infected offspring
Researchers have shown that brain activity of Ndel1, an enzyme that plays an important role in neuron differentiation and migration, decreased in mice infected by Zika during pregnancy.
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Features
The diverse industrial applications of microbial pectinases
With the increasing demand for pectinases, there is a need to enhance production and search for new applications.
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Barnacle-like sticky protein suggests ocean origin for Candida auris
Candida auris is unlike any other known fungus in that it employs a type of protein, called an adhesin, that acts very similar to those used by oceanic organisms, such as barnacles and mollusks.
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Recombinant hydrophobic protein acts as toxin-free fire retardant on textiles
Researchers have discovered that recombinant hydrophobic protein can act as a fire retardant when applied to textiles, eliminating the need for toxic chemicals.
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Scientists reveal inner workings of Ebola’s ‘viral factories’
A new study reveals how the Ebola virus’s replication machinery forms fascinating microscopic structures inside host cells that become viral factories.
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Unraveling cell death protein may inspire new biotechnology tool
Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool. The protein belongs to the ‘superfamily’ of Argonaute proteins, which previous research has suggested ...
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Fly toolkit created for investigating COVID-19 infection mechanisms
A new ‘fly-to-bedside’ resource offers a shortcut for developing drug therapies needed for long COVID and future coronavirus outbreaks.
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Researchers uncover novel bacterial communication system to combat AMR
Using a sophisticated mass spectrometry technology developed at SMART and MIT, researchers have discovered that the enzyme RlmN is a stress sensor for reactive oxygen species (ROS) – highly reactive molecules which can cause damage to bacteria. Source: SMART AMR (L to R) SMART researchers Dr Cui Liang, ...
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New bacterial blueprint will help fight antibiotic resistance
Scientists have gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.
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New enzyme designed using Antarctic bacteria and computer calculations
For the first time, researchers have succeeded in predicting how to change the optimum temperature of an enzyme using large computer calculations and based on a cold-adapted enzyme from an Antarctic bacterium.