All Proteomics & Enzymology articles
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Scientists discover how innate immunity envelops bacteria
The human protein GBP1 fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now. Researchers have unravelled how this protein operates.
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Selfishness mechanism points way to optimizing inhibitors that fight antibiotic resistance
Resistance can be fought by targeting bacteria that are ’selfish’ with their antibiotic resistance tools, according to a new study.
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Scientists discover viral trapdoor blocking HIV and herpes
A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them ...
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Scientists engineer new enzyme to produce synthetic genetic material
Researchers have engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA advances the discovery of therapeutic options to treat cancer and other diseases.
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Study finds persistent infection could explain long COVID in some people
Researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.
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Scientists develop enzyme complex to find Achilles heel of protozoan parasite
In an effort to find a new weak spot of the protozoan parasite Trichomonas vaginalis, researchers have succeeded in preparing a key enzyme complex – the proteasome.
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Scientists unravel the secrets of the spiral bacterium
A team of researchers has discovered the mechanism that determines the spiral shape of Rhodospirillum, shedding new light on the link between cell shape and fitness.
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Plastic-eating enzyme identified in wastewater microbes
Plastic pollution is everywhere, and a good amount of it is composed of polyethylene terephthalate (PET, ♳). This polymer is used to make bottles, containers and even clothing. Now, researchers report in ACS’s Environmental Science & Technology that they have discovered an enzyme that breaks apart PET ...
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Filament structure activates and regulates CRISPR-Cas ‘protein scissors’
Researchers have revealed the structure of the CRISPR-Cas ‘protein scissors’ found in bacteria and provided mechanistic details on how they function.
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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Study unveals a novel protective mechanism in bacterial cell wall
Researchers from Umeå University, Sweden, and Cornell University, USA, have discovered a widespread mechanism in bacteria that enhances the bacteria’s defense against environmental threats. Source: Umeå University Sara Hernandez and Laura Alvarez, two of the researchers behind the study in the lab. The discovery, which may be ...
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Bacterial ‘flipping’ allows genes to assume different forms
A new study has shown that inversions, which cause a physical flip of a segment of DNA and change an organism’s genetic identity, can occur within a single gene, challenging a central dogma of biology — that one gene can code for only one protein.
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Scientist devises test feed for fungal ‘micro-machine’ that breaks down wood
Researchers investigating a molecular machine found in fungi that decomposes wood into its basic components have come up with a test feed that allows them to observe its close-to-natural action, opening the door to putting it to industrial application.
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Scientists unveil how the oceans’ most abundant bacteria impact global nutrient flows
A new paper has revealed how key bacterial proteins contribute to global carbon, sulfur and other nutrient cycles.
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Extreme microbe reveals how life’s building blocks adapt to high pressure
An AI tool has helped scientists discover how the proteins of a heat-loving microbe respond to the crushing conditions of the planet’s deepest ocean trenches, offering new insights into how building blocks of life might have evolved under early Earth conditions.
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Scientists close in on mystery of deadly Hep C virus
A new study by a cross-disciplinary research team has identified the protein complex at the surface of the hepatitis C virus that enables it to bind to human cells, opening a pathway to vaccine candidates that can prevent the virus from infecting the cells.
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Study of mosquito spit could lead to therapies for viruses like West Nile and yellow fever
Researchers are analyzing samples of noninfectious mosquito saliva in the fight against arboviruses — viruses spread by arthropods like mosquitoes.
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Surprise find in study of environmental bacteria could advance search for better antibiotics
In what they labeled a “surprising” finding, researchers studying bacteria from freshwater lakes and soil say they have determined a protein’s essential role in maintaining the germ’s shape.
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Researchers find promising new weapon against certain types of antibiotic-resistant bacteria
Researchers have discovered a new combination of substances that appears to combat a range of bacteria that causes conditions such as stomach ulcers and urinary tract infections, and that are increasingly developing antibiotic resistance.
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Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease.