All Pharmaceutical Microbiology articles – Page 8
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NewsScientists develop an innovative compound effective against malaria and leishmaniasis
Initially designed for malaria, this drug shows high efficacy against leishmaniasis, representing a unique and promising breakthrough for the treatment of both infections.
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NewsNew enzymatic cocktail can kill tuberculosis-causing mycobacteria
A new study shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
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NewsResearchers a step closer to a cure for HIV
A new study demonstrates that a patented therapeutic candidate, an HIV-virus-like-particle (HLP), is 100 times more effective than other candidate HIV cure therapeutics for people living with chronic HIV on combined antiretroviral therapy (cART).
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NewsMaleimide derivative shows promise for treating clinical candidiasis
A new study demonstrates the efficacy of a novel maleimide analogue as a novel antifungal compound, highlighting its potential as a promising option for the treatment of clinical candidiasis.
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NewsBreakthrough antibiotic shows promise against obstinate mycobacterial infections
Researchers assemble a new antibiotic candidate, COE-PNH2, offering a more effective therapeutic option against hard-to-treat mycobacterial lung diseases.
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NewsCancer therapies show promise in combating tuberculosis
A study has identified a combination of medications that may improve blood flow within granulomas, tight clusters of white blood cells formed by the body’s immune system in response to tuberculosis infection, benefiting drug delivery.
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OpinionAntimicrobial chemotherapy - which direction now?
The answer to antimicrobial resistance might not be the continual discovery of new antibiotics - but judicious use of the antibiotics and insights into antibiotic producing organisms we have already discovered.
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NewsResearch uncovers a new path to drug diversity
By exploring protein evolution, scientists have found new “fusion sites” that enable faster and more targeted drug development.
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NewsResearchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.
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NewsTeardrops target multiple COVID variants through the twist in the spike protein
Particles that gum up the keys that the virus uses to enter cells could one day be an effective COVID treatment whenever vaccines and other treatments fall short.
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NewsDrug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction
Scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
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NewsDaff-derived Alzheimer’s drug fermented with help from AI and bacteria moves closer to reality
An innovative approach uses artificial intelligence and biosensors to pave the way for faster drug development.
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NewsLongitudinal gut fungal alterations and potential fungal biomarkers for the progression of primary liver disease
Scientists have found that during liver disease progression, the abundance of Chytridiomycota increased initially, but was later replaced by Ascomycota in HCC.
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NewsNew bioengineered protein design shows promise in fighting COVID-19
Researchers have designed a novel protein capable of binding to the spike proteins found on the surface of the coronavirus, allowing them identify and recognize the virus for diagnostic purposes, and to hinder its ability to infect human cells.
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NewsInsights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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NewsRevolutionary chronic wound treatment could help millions
A team of scientists has developed an effective treatment for preventing infection in chronic wounds involving the plasma (electrical gas) activation of hydrogel dressings to produce a unique mix of different chemical oxidants.
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NewsSteroid drugs used for HRT can combat E. coli and MRSA
New research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
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NewsNew dual therapeutic strategy shows promise against multidrug-resistant salmonella
A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports. Source: CDC/ Antibiotic Resistance Coordination and Strategy Unit Medical illustration of drug-resistant, nontyphoidal Salmonella sp. ...
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NewsResearchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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NewsLong-acting HIV treatment benefits adults with barriers to daily pill taking and adolescents with suppressed HIV
Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral suppression.
