All Pharmaceutical Microbiology articles – Page 6
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NewsResearchers rescue antibiotics from resistance using phototherapy
Researchers have used phototherapy to inhibit a protein in E. coli bacteria that makes them resistant to antibiotics. This new method, if proven safe and effective in living organisms, holds promise for rescuing the effectiveness of antibiotics that bacteria have become resistant to.
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NewsA viral fitness-constraint strategy exploits the structural and functional limitations of viral evolution
Researchers have revealed two innovative strategies for the development of durable and broadly neutralizing antibodies against SARS-CoV-2. Their study proposes the immune trajectory strategy and the viral fitness-constraint strategy.
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NewsCorticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and acute respiratory distress syndrome and may reduce secondary shock in severe pneumonia.
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NewsUnder The Lens: Callum Cooper explores how bacteriophages could revolutionise medicine - and how we get to that point
In a compelling new video interview from Applied Microbiology International’s ‘Under the Lens’ series, Dr. Callum Cooper shares fascinating insights into one of medicine’s most promising frontiers: phage therapy.
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NewsNew guideline on pre-exposure and postexposure HIV prevention
Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these options to patients.
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NewsGlobal Virus Network issues warning on the Marburg virus outbreak in Ethiopia
The Global Virus Network (GVN) has issued a statement on the newly confirmed outbreak of Marburg virus disease (MVD) in southern Ethiopia. This represents the country’s first documented outbreak of Marburg virus and raises urgent public health, research, and surveillance imperatives.
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NewsFractional-dose vaccines can save millions during shortages
New research shows that using smaller, fractional doses of vaccines can significantly reduce infections during epidemics, especially when vaccine supply, delivery, or administration capacity is limited.
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NewsCuring hepatitis C can rebalance immunity in Indonesians living with HIV
A new study provides the first longitudinal immunological data on HIV/HCV-coinfected individuals in Southeast Asia, underscoring the importance of early hepatitis C treatment to prevent long-term immune and liver complications.
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NewsParkinson’s drug offers basis for new hospital bacterium anti-infectives
Researchers have discovered a promising starting point for the development of new active substances against the hospital germ Pseudomonas aeruginosa.
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NewsExperimental mRNA therapy shows potential to combat antibiotic-resistant infections
Researchers have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria. In preclinical studies, the therapy slowed bacterial growth, strengthened immune cell activity, and reduced lung tissue damage in models of multidrug-resistant pneumonia.
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NewsNew collection of bacteria-eating viruses can tackle hospital superbug
An international team of researchers have comprehensively catalogued a new collection of bacteria-eating viruses called phages sourced, in part, from hospital wastewater. The phages have been shown to be effective against different strains of Klebsiella pneumoniae.
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NewsSnakebites: COVID vaccine tech could limit venom damage
The same technology used in COVID-19 vaccines could help prevent muscle damage from snakebites, according to scientists who say it could be even more useful for other conditions where toxins cause harm gradually, such as blocking harmful toxins produced by bacteria during infections.
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NewsScientists uncover how COVID-19 variants outsmart the immune system
Researchers have created the most comprehensive map to date showing how antibodies attach to the SARS-CoV-2 virus, which causes COVID-19, and how viral mutations weaken that attachment.
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NewsWorld’s largest metabolomic study completed, paving way for predictive medicine
UK Biobank has today released the final set of data on nearly 250 metabolites in half a million volunteers. This completes the world’s largest ever metabolomic study, which will help drive treatment strategies for neurological conditions, heart disease and cancer.
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NewsResearchers boost biosynthetic capacity in yeast through extended lifespan
Scientists have demonstrated that combining lifespan engineering strategies with metabolic pathway optimization in Saccharomyces cerevisiae enables highly efficient sclareol biosynthesis, marking an advance in improving microbial production through lifespan engineering.
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NewsScientist who harnesses bacteria to deliver green solutions is winner in 2025 Tata Transformation Prize
A scientist who harnesses bacteria to deliver green solutions has been named as one of the winners of the 2025 Tata Transformation Prize. Balasubramanian Gopal, PhD, Indian Institute of Science, has been named Sustainability Winner in the awards.
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NewsPhase 2 clinical trial results show potential to shorten TB treatment time
New clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
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NewsMedications change our gut microbiome in predictable ways
A study shows that many of the changes to the gut microbiome are driven by competition for nutrients – medications reduce certain bacterial populations and change the availability of nutrients, and the bacteria most able to capitalize on those changes are the ones to survive.
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NewsSugar transporter discovery offers promising avenue for improving antibiotic efficacy
Scientists have recently demonstrated that aminoglycosides enter bacteria by using sugar transporters. They have also successfully doubled the number of transporters, even in the most resistant Escherichia coli strains, thus improving antibiotics’ penetration rate and efficacy.
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NewsStudy in Europe: monoclonal antibodies effectively prevent respiratory syncytial virus in infants
Data from Belgium, Portugal and Spain show that immunisation of children after birth reduced the risk of hospitalization due to RSV infection by almost 80%.