All Pharmaceutical Microbiology articles – Page 4
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Llama nanobodies deliver breakthrough in building HIV immunity
Scientists have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source — llamas.
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FedEx opens first European Life Science Center in Veldhoven
Federal Express Corporation, the world’s largest express transportation company, has opened its first European Life Science Center in Veldhoven, the Netherlands. The specialised cooling facility opens global access for the healthcare industry.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Careers
Drug discovery and a valuable chance to network: Ugochukwu Anieto on a fascinating experience at ASM 2024
Professor Ugochukwu Anieto of Texas A&M University reveals how AMI’s Scientific Event Travel Grant helped him to gather some fascinating insights on antimicrobial compounds at the recent ASM conference.
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Scientists pioneer comprehensive derivative synthesis method for developing new antimicrobial drugs
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
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Scientists isolate amylase enzyme produced by indigenous bacteria from sugar factory waste
Experts in wastewater processing and treatment have isolated amylase-producing bacteria from the liquid waste of sugar local factories and optimized the production of the amylase enzyme.
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New species of insect-parasitising fungus discovered in lower Himalayas
Researchers have discovered a new species of fungi, Ophiocordyceps, in the lower Indian Himalayas. These fungi - fictionalised as the deadly fungi in The Last of Us - are well known as parasites of insects and are often prized for their medicinal qualities.
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Scientists uncover molecular basis of how potential anti-Covid drug binds to viral N-glycan
Researchers evaluating the potential of naturally occurring pradimicin A (PRM-A) as a new anti-SARS-CoV-2 drug that suppresses SARS-CoV-2 transmission investigated how exactly PRM-A binds to the viral N-glycans.
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Careers
Connecting with microbiologists and presenting research: Oluwole Owoyemi reports back from ASM 2024
Medical microbiologist Oluwole Owoyemi of Achievers University Owo and Federal University of Technology, Akure, reports back from ASM MICROBE 2024 after being awarded a Scientific Event Travel Grant by Applied Microbiology International.
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Cancer drug could be repurposed to fight Covid-19
Twelve years ago, cancer researchers identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19.
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Scientists unravel life-saving effect of dexamethasone in COVID-19
Researchers have discovered how the cortisone compound dexamethasone influences the impaired inflammatory response to Covid-19 and which patients benefit from it.
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Treatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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Coumarin glycosides reverse enterococci-facilitated enteric infections
Researchers have developed a dietary therapeutic for enterococci-mediated infections.
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Researchers harness intratumoral microbiome against colorectal cancer
Scientists have established a microbiota-targeted drug delivery system that exhibits high efficiency in colorectal cancer targeting and colon retention.
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Researchers deploy E coli to selectively target tumor cells
Scientists explore how an engineered bacterium limits tumor growth and maximizes targeted anticancer drug delivery.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Bacteria discovery leads to novel probiotic for eczema
Research has led to the availability of a new over-the-counter topical eczema probiotic, based on the discovery that bacteria present on healthy skin called Roseomonas mucosa can safely relieve eczema symptoms in adults and children.
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Novel method for synthesis of coral-derived compound offers hope for non-toxic fouling agents
Researchers have developed a novel total synthesis method for scabrolide F, a natural compound derived from corals, and revealed its antifouling properties.
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Marine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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Diagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.