All Pharmaceutical Microbiology articles – Page 3
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Researchers find promising new weapon against certain types of antibiotic-resistant bacteria
Researchers have discovered a new combination of substances that appears to combat a range of bacteria that causes conditions such as stomach ulcers and urinary tract infections, and that are increasingly developing antibiotic resistance.
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New study looks at drug exposures of COVID-19 therapy for pregnant women
A new study provides important insights into the pharmacokinetics and safety of intravenous remdesivir in treating the SARS-CoV-2 coronavirus in pregnant women.
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3D bioprinting advances research on respiratory viruses
A research team has successfully created artificial lungs, designed to study infections and test drugs for respiratory diseases including COVID-19.
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Breakthrough in the synthesis of fungal bioactive compounds for therapeutic applications
Researchers have developed an efficient method to synthesize eutyscoparol A and violaceoid C, two promising bioactive compounds that are produced by fungi.
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Dengue vaccine is effective and safe, reveals first global meta-analysis
The study, conducted by cross-referencing data from 19 scientific studies, involving over 20,000 individuals, shows an efficacy rate of over 50% in reducing disease cases, with lasting effects and a high safety profile.
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Multi-omics strategy reveals how insect parasite fungus ameliorates sepsis-associated acute kidney injury
Scientists have found that Cordyceps sinensis significantly ameliorates renal injury and inflammation in sepsis-associated acute kidney injury (S-AKI) by regulating mitochondrial energy metabolism and macrophage polarization.
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Researchers create new treatment and vaccine for flu and various coronaviruses
A team of researchers has discovered two new ways of preventing and treating respiratory viruses using nasal sprays.
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Researchers engineer ‘cat parasite’ Toxoplasma gondii to release therapeutic proteins in the human brain
In a breakthrough study by an international team of scientists, the ‘cat parasite’ Toxoplasma gondii was engineered to deliver drugs to the human brain.
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New study highlights scale and impact of long COVID
A wide range of biological mechanisms are involved in long Covid, including persistence of the original virus in the body, disruption of the normal immune response, and microscopic blood clotting, even in some people who had only mild initial infections.
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Super cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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‘Russian doll’ packaging could boost drug delivery
Researchers have developed a new technology that lets them create compartments within compartments on the nanoscale, which can mean timing drug release for maximum effect at the site where it’s most needed.
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Chinese medicinal fungus shows promise in treating idiopathic pulmonary fibrosis
A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.
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Exploratory analysis associates HIV drug abacavir with elevated cardiovascular disease risk in large global trial
Current or previous use of the antiretroviral drug (ARV) abacavir was associated with an elevated risk of major adverse cardiovascular events (MACE) in people with HIV, according to an exploratory analysis from a large international clinical trial primarily funded by the National Institutes of Health (NIH). There ...
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Dual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research
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New agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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Isolated viral load test may generate false positive results for people using long-acting PrEP
A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.
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Peptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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Expiring medications could pose challenge on long space missions
Medications commonly used by astronauts aboard the International Space Station might be ineffective or harmful on a multi-year mission to Mars, a new study suggests.
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New drug target identified for diseases associated with leukemia-causing virus
Researchers have found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). Blocking kinases, which regulate cellular functions, leads to cell death caused by the degradation of the protein Tax.
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Scientists pinpoint new drug target for RSV
Scientists have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an exciting new target for drug developers.