All Pharmaceutical Microbiology articles – Page 3
-
NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.
-
News‘Known’ TB gene springs to action under stress, with an unexpected biological role
New research has discovered that one of TB’s supposedly “known” genes has a completely unexpected biological role, with far-reaching implications.
-
NewsPreventive TB treatment for individuals with HIV shown to be effective in real-world settings
A new study has evaluated the real-world impact of TB preventive treatment in six countries with high TB and HIV rates and highlights the importance of preventive treatment in reducing deaths caused by a curable disease.
-
NewsEngineered macrophages gain enhanced bacteria-targeting ability
A novel membrane interface engineering strategy enables immune cells to specifically recognize, capture and eliminate pathogenic bacteria without genetic modification.
-
NewsResearchers identify rapidly spreading genetic variants that make parasites resistant to malaria treatment
New genetics study helps explain declining malaria drug susceptibility and highlights the urgent need to track mutations and improve current therapies.
-
NewsAlbumin is prevented from crossing the placenta – opening opportunities for design of long-acting biologic medicines
Researchers have uncovered that the placenta distinguishes between antibodies and albumin, a finding that may reshape the future design of biologic medicines with reduced fetal exposure.
-
NewsCell ‘invisibility cloaks’ could offer side-effect-free diabetes treatment
New research suggests manufacturing cells an “invisibility cloak” out of a jelly-like material known as hydrogel, may offer an easier, less damaging treatment pathway for people with diabetes undergoing cell therapy.
-
NewsUC San Diego receives $12.3 million grant to study the intersection of HIV and methamphetamine use
A newly funded programme aims to use a multidisciplinary approach focused on improving the clinical care and brain health of people with HIV who also have an active methamphetamine use disorder.
-
NewsStable RNA elements open new possibilities for mRNA therapeutics
New research has discovered compact viral RNA elements that can make mRNA more stable, and could provide a simple way to develop longer-lasting and more efficient mRNA technologies for vaccines and other RNA-based therapeutics.
-
NewsNovel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model capable of predicting cancer subtypes, specific genetic mutations, and survival outcomes across 32 different cancers.
-
NewsImmune molecules play a limited role in ALS progression
New research indicates that immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.
-
NewsPregnancy increases immune burden on women with arthritis and lupus
New research finds that the immune system of women with autoimmune diseases such as rheumatoid arthritis and lupus react very differently to pregnancy: rheumatoid arthritis patients often experience an improvement in symptoms, while lupus patients have an elevated risk of deterioration.
-
NewsVanderbilt health evaluating vaccine for C. difficile for people 65 and older
Investigators are enrolling participants in a Phase 3 clinical trial testing an investigational vaccine against Clostridioides difficile, a contagious bacterial infection of the colon.
-
NewsCould preventing shingles also help prevent dementia?
A new study finds that older adults who received a shingles vaccine had a 24% lower risk of developing dementia over four years. The findings add to growing evidence that preventing shingles may also protect against neurological disease.
-
NewsWorld’s first oral microbiome-based nanomedicine to supercharge anti-cancer immunity
Researchers have successfully developed the world’s first oral, microbiome-based nanomedicine which enhances the ability of immune cells to attack cancer cells.
-
NewsSteroids reduce inflammation in chronic mycobacterial lung infections without limiting antimicrobial defence
Researchers have shown that dexamethasone, a commonly prescribed anti-inflammatory steroid, can reduce harmful inflammation triggered by Mycobacterium avium without weakening the ability of human immune cells to control the infection.
-
NewsLong-acting therapies continue to gain momentum in HIV, says GlobalData
The next phase of competition in the HIV market will be defined not only by achieving viral suppression, but improving treatment adherence, reducing medication burden and delivering more convenient treatment options, says a new analysis.
-
NewsTriple-dose regimen may permanently clear HIV in infected newborns
New research suggests a one-time regimen of therapies given to newborns within three days of birth could permanently clear HIV infection.
-
NewsNew viral marker strategies improve prediction of functional cure in chronic hepatitis B
Researchers identify how combining classical and emerging viral biomarkers can better predict functional cure and guide individualized hepatitis B treatment.
-
NewsObesity drug significantly reduces the risk of infections and serious cardiovascular events
Tirzepatide, marketed under the brand name Mounjaro, could reduce the risk of heart attacks and hospitalizations due to infections in people with type 2 diabetes by by about one-third when compared with a conventional diabetes medication.