All Pharmaceutical Microbiology articles – Page 10
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NewsEnzyme that reproduces Meinwald reaction offers hope as bionanomachine for green chemistry
Researchers have for the first time precisely characterised the enzyme styrene oxide isomerase, which can be used to produce valuable chemicals and drug precursors in an environmentally friendly manner.
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NewsAncient remedy is reworked to create medicinal cocktail targeting drug-resistant bacteria
A mediaeval remedy used to cure a “lump in the eye” - interpreted as a sign of bacterial infection - more than 1,000 years ago has been reworked into a pharmaceutical product with potent antibiofilm activity, delegates will hear at the Letters in Applied Microbiology ECS Research Symposium.
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NewsKeto diet boosts lifesaving antifungal drug in mice
In animal tests, researchers have found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus behind fungal meningitis than taking the medication alone.
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NewsUT Health San Antonio to lead $11m study of a first-ever oral chlamydia vaccine
The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a cooperative agreements research project grant.
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NewsResearchers may have found an Achilles heel for Hepatitis B
Researchers have revealed never-before-seen mechanisms that may lead to new therapeutic approaches for HBV.
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NewsScientists probe spermidine production to combat emerging drug resistance in Salmonella
Scientists have pinpointed how Salmonella Typhimurium uses a key molecule called spermidine to shield itself from the onslaught of the host’s defence machinery - and an existing FDA-approved drug can reduce spermidine production.
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NewsDecoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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NewsAn adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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NewsTenofovir alafenamide treatment achieves positive results in Chinese chronic hepatitis B patients
A five-year treatment regime with tenofovir alafenamide achieves high rates of viral suppression, alanine aminotransferase normalization, and favorable bone and renal safety in Chinese chronic hepatitis B patients.
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NewsStudy finds diabetes drug reduces COVID-19 viral load and viral rebound
Researchers have found that metformin, a drug commonly used to treat diabetes, can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment.
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NewsNano-drugs hitching a ride on bacteria could help target hard-to-reach pancreatic cancer
Employing bacteria to infiltrate the dense matrix of collagen and other tissues surrounding pancreatic tumors and deliver drugs could aid treatment for pancreatic cancer.
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NewsOrangutan treats wound with antimicrobial, pain-relieving plant
A Sumatran orangutan with a facial wound ate and repeatedly applied sap from a plant with anti-inflammatory and pain-relieving properties commonly used in traditional medicine. He also covered the entire wound with the green plant mesh.
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NewsWomen need better treatments for bacterial vaginosis: call
Researchers at the University of Maryland School of Medicine are calling for robust studies for a treatment already used in Europe.
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NewsAntimicrobial peptide from cows delivers way to kill hypervirulent bacteria
An antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae.
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NewsPioneering oral fungal infection treatment shows promise in preclinical trials
A novel oral amphotericin B (MAT2203) developed for treatment of invasive mucormycosis (IM) and other deadly invasive fungal infections, has demonstrated encouraging results in a series of preclinical studies.
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NewsStudy details a common bacterial defense against viral infection
One of the many secrets to bacteria’s success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves. Source: Mogana Das Murtey and Patchamuthu Ramasamy Bacillus cereus, SEM image Technological advances have enabled recent ...
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NewsExperts developing immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body’s own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.
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NewsSynthetic droplets cause a stir in the primordial soup
A synthetic droplet may give researchers clues on how the simplest forms of life on the planet could navigate their surroundings.
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NewsPaclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
A study finds that Paclitaxel treatment directly promotes HBV replication and transcription, leading to HBV reactivation in HBV stable expression cell models, HBV natural infection cell models, and HBV transgenic mouse models.
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NewsStudy finds artificial intelligence can develop treatments to prevent superbugs
Researchers developed an AI model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations.