All Pharmaceutical Microbiology articles
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NewsNew antimalarial drug candidate shows potential for fighting resistance and reducing malaria transmission
Researchers have developed a new antimalarial drug candidate designed to address the growing challenge of drug resistance and potentially reduce malaria transmission.
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NewsCancer-fighting bacterial product ‘cocktails’ may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to researchers who devised a new approach of creating bacteria-derived mixtures — or cocktails — to help fight bladder cancer. They found that the cocktails significantly boost the immune system’s ability to fight cancer.
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NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
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NewsStrategic advancement of second-generation fungal vaccine VXV-01 through Phase 1 trials
The Lundquist Institute (TLI) and its start-up company Vitalex Biosciences (Vitalex) have announced that the second-generation fungal vaccine candidate known as VXV‑01 is poised to move forward in development up to and including Phase 1 clinical evaluation.
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NewsMutated baker’s yeast at the forefront of petroleum substitute tech
Researchers engineering Saccharomyces cerevisiae to produce 2,3-butanediol (2,3-BDO) introduced mutations into the genomic DNA. The researchers engineered four altered strains and subjected them to ethanol, heat, and low pH stressors.
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NewsUnique bond identified as key to viral infection speed
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research reveals a deliberate imbalance in their shape that helps them infect their hosts.
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NewsOpioid use linked to higher risk of C. difficile infection
New research from the University of Georgia suggests that opioid use could make patients more vulnerable to infections. The meta-analysis examined four studies of almost 120,000 patients. The researchers found that about 31% of patients who were prescribed and taking opioids caught C. diff, compared to 17% of patients who weren’t using them.
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NewsCloves and miswak: Antimicrobial effects of Syzygium aromaticum and Salvadora persica against common pathogens in vitro
Clove essential oil (CEO) derived from Syzygium aromaticum and miswak (Salvadora persica) contains bioactive compounds with antimicrobial properties. This study aimed to evaluate the in vitro antimicrobial efficacy of CEO, miswak, and their combination against key peri-implantitis pathogens.
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NewsNew method to accelerate vaccine and drug development for norovirus
Researchers have developed a simple and efficient system for understanding the functions of specific norovirus genes, providing new avenues for developing antivirals and vaccines.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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NewsOld molecules show promise for fighting resistant strains of COVID-19 virus
SARS‑CoV‑2 continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid. Now, researchers have identified several promising molecules that could lead to new medications capable of combating these resistant variants.
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NewsNature’s 10: Ten people who shaped science in 2025
Microbiologists and scientists tackling infectious diseases are among Nature’s annual list of ten people at the heart of some of the biggest science stories of 2025.
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NewsEngineered virus boosts immune response against glioblastoma in preclinical models
Researchers have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models.
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NewsSocial lives of viruses affect antiviral resistance
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.
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NewsPlant phenolic acids supercharge old antibiotics against multidrug resistant E. coli
Plant derived phenolic acids can dramatically enhance the activity of existing antibiotics against multidrug resistant E. coli, offering a promising new tool in the global fight against antimicrobial resistance.
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NewsStudy shows robust immune responses to H5N8 avian influenza vaccine
A new study shows that the MF59-adjuvanted A(H5N8) vaccine induced strong immune responses, including both functional antibodies and memory T-cell responses, against the vaccine virus, as well as against H5 viruses that have caused recent outbreaks in Europe and the United States.
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NewsChemists synthesize a fungal compound that holds promise for treating brain cancer
For the first time, chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent.
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NewsLight-sensitive microbial protein may herald new cancer therapies
Researchers used a mouse cancer model to show that tumors expressing Archaerhodopsin 3 shrink after exposure to green light.
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NewsCommon water pill may help HIV medicines work faster and reduce inflammation, early study suggests
Adding a readily available diuretic to standard HIV therapy appears to reduce circulating virus by four-fold, a new study shows. Researchers treated HIV-infected mice with human immune cells with first‑line antiretroviral therapy plus a long‑acting form of spironolactone.
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NewsResearchers rescue antibiotics from resistance using phototherapy
Researchers have used phototherapy to inhibit a protein in E. coli bacteria that makes them resistant to antibiotics. This new method, if proven safe and effective in living organisms, holds promise for rescuing the effectiveness of antibiotics that bacteria have become resistant to.