All Pharmaceutical Microbiology articles
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NewsStudy of hemp microbiomes may lead to more sustainable farming methods
A new study of hemp microbes may help scientists create special mixtures of helpful microbes to make hemp plants produce more CBD or have better-quality fibers.
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NewsNew insights offer hope for developing antiviral therapeutics targeting mpox
New research provides novel perspectives on the biological function of G4s in the lifecycle of MPXV and offer potential avenues for developing antiviral therapeutics targeting mpox prevention and treatment.
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NewsScientists explain how a compound from sea sponge exerts its biological effects
Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now researchers have a better idea of how it works.
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NewsSmall antibody offers broad protection against influenza
Researchers have discovered an antibody-like molecule that can protect mice from various influenza viruses. The findings could pave the way for new treatments and the development of broader influenza vaccines.
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NewsCARB-X funds Peptilogics to develop a novel, broad-spectrum therapeutic to treat fracture-related infections
CARB-X will award Peptilogics US$3.3 million to develop and execute a workplan for its slow-release formulation of a novel, broad-spectrum therapeutic, zaloganan-CR, an engineered peptide intended for use in preventing infection after high-energy-traumatic bone injuries.
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NewsScientists advance nanobody technology to combat deadly Ebola virus
Researchers have developed the first nanobody-based inhibitors targeting the Ebola virus. Their small size allows them to access areas of the virus and human tissues that larger antibodies cannot.
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NewsCompound derived from Brazilian plant acts against parasite that causes visceral leishmaniasis
A compound derived from Nectandra leucantha, a tree native to southern Brazil (local names canela-seca or canela-branca), has the potential to be used to treat visceral leishmaniasis, a neglected tropical disease.
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NewsOvercoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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NewsAs prevention strategy for sexually transmitted infections rolls out, experts highlight both promise and knowledge gaps
Real-world evidence demonstrates that the postexposure strategy of doxy PEP is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.
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NewsResearchers discovered replication hubs for human norovirus
Researchers have reported the discovery of replication hubs for human norovirus, which could lead to designing antiviral drugs to prevent, control or treat these infections.
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NewsTinkering with the ‘clockwork’ mechanisms of life
Scientists have successfully recreated and validated two distinct mechanisms that can program both the activation and deactivation rates of nanomachines in living organisms across multiple timescales.
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NewsNature’s instructions: How fungi make a key medicinal molecule
Scientists outline how they deciphered nature’s own instructions — namely, the genes of the mold Penicillium citrinum — to discover a previously unreported enzyme that catalyzes the creation of cyclopentachromone-containing compounds.
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NewsApplication of heavy-ion irradiation mutagenesis to improve the production efficiency of the antifungal drug micafungin
Scientists have used heavy-ion irradiation to improve efforts to produce the semisynthetic echinocandin antifungal agent micafungin which derives from fungal natural product FR901379 produced by Coleophoma empetri.
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NewsDiscovery of β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition in Serratia marcescens
A new study has identified β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens.
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NewsScientists offer user manual for yeast’s genetic switches
Scientists have found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production using yeast.
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NewsNew discovery provides hope in fighting drug-resistant malaria
Researchers have described how they may have found a new target in Plasmodium falciparum, the deadliest malaria parasite: a cholesterol-managing protein called PfNCR1.
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NewsStudy shows drop in use of antiviral medications in young children with influenza
Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a recent study reports an underuse of the treatment.
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NewsNew guidelines unveil advanced strategies for HIV treatment and prevention
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV, based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.
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NewsBreakthrough of the Year: A drug that prevents HIV infection, providing six months of protection per shot
As its 2024 Breakthrough of The Year, Science has named the development of lenacapavir – a promising new injectable drug that prevents HIV infection. The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein.
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NewsA new class of antivirals could help prevent future pandemics
A new study introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, including Ebola and dengue, as well as cytosolic-replicating DNA viruses, including Pox viruses.
