All Phage Therapy articles – Page 2
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Major antimicrobial power boost as phages form into surprising flower shapes
Researchers treated bacteria-eating viruses so they could be viewed alive under an electron microscope and coaxed them to join together into flower-like shapes - discovering that this made them 100 times more efficient.
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Phages could replace harmful pesticides with a cleaner, greener alternative
Use of phage therapy in farming could be valuable in replacing chemical pesticides with a safer and greener alternative, helping to address climate change, according to a new review in Sustainable Microbiology.
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Viruses are teeming on your toothbrush and shower head
There’s a jungle of ‘untapped biodiversity’ in the bathroom, a new study finds.
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Bacteria-fighting viruses team up to treat drug-resistant superbugs
Researchers screened a library of bacteriophages to find combinations of the viruses that can work together to fight antibiotic-resistant Klebsiella pneumoniae infections.
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Careers
A fresh perspective on phages - AMI intern Helen Kinchin opens up on her new PhD topic
What’s it like at the start of a career working with bacteriophages? Applied Microbiology International intern Helen Kinchin, who recently began a PhD at the University of Warwick, reveals her experiences.
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Careers
Viruses of Microbes 2024
Discover the benefits of attending a scientific conference. This year, VoM2024 was held in Cairn, Australia.
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New phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
Scientists have developed a technology that lets them edit the genomes of phages in a streamlined and highly effective way, giving them the ability to engineer new phages and study how the viruses can be used to target specific bacteria.
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Dormancy defence systems show us why phages may not be the answer to everything
Toxin/antitoxin defence systems in bacteria need to be better understood if the potential of phage therapy is to be realised, a new review in Sustainable Microbiology suggests.
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Scientists unveil first complete image of the PARIS system
A new study explores the PARIS immune system, which bacteria use to protect themselves against viral infections and which stands for Phage Anti-Restriction Induced System.
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3D shapes of viral proteins point to previously unknown roles
Scientists uncover an ancient immune-evading strategy shared by animal viruses and viruses that infect bacteria; findings may help in the development of new antiviral therapies.
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Infected bacteria fight back with ‘hidden’ genes that halt cell growth, slow viral spread
Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth.
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Coinfecting viruses impede each other’s ability to enter cells
Scientists researching phage infection at the level of a single cell investigated whether the number of infecting phages that bind to the bacterial surface corresponds to the amount of viral genetic material that is injected into the cell.
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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Researchers unveil secrets behind phages’ flawless timing
New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Researchers develop a way to make lifesaving phages accessible, transportable and much easier to use
Researchers have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them.
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Phage-derived enzyme targets biofilms to mitigate acute graft-versus-host disease
Scientists investigating acute graft-versus-host disease probe gut microbiome to detect presence of a bacteriophage-derived enzyme known as endolysin, exhibiting potent antibacterial activity specifically targeting E. faecalis.
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‘Sacrifice’ of virus data clears the path to open a disease discovery pipeline
Researchers are analysing viruses in human populations – and on coral reefs – to build a robust method of identifying viruses in all animals, plants and environments, and to show the flexibility of the pipeline for future research.
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Phage‐display tech boosts targeting ability of antimicrobial peptides against Staphylococcus aureus
Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have shown promising applications. Source: CDC/ Matthew J. Arduino/ Janice Haney Carr Under a very high magnification of 20,000x, this scanning electron micrograph ...
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Careers
A day in the life of a phage expert
Nicolás Cifuentes is Head of Research Projects and Phages at PhageLab, Chile, which offers tailor-made solutions to control bacterial outbreaks in the livestock and poultry industries.