All Phage Therapy articles
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News
Researchers hope to develop novel drugs for gastrointestinal disorders by fermenting feces
In a new study, researchers have been cultivating ‘good viruses’ from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants and improve this life-saving treatment through standardization.
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Meet the Global Ambassadors: Our Q&A with Matthew B Sullivan
The Microbiologist chats with our new Global Ambassador for the United States, Matthew B Sullivan, who is Professor of Microbiology and Director of the Center of Microbiome Science, at The Ohio State University.
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Structural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
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Major antimicrobial power boost as phages form into surprising flower shapes
Researchers treated bacteria-eating viruses so they could be viewed alive under an electron microscope and coaxed them to join together into flower-like shapes - discovering that this made them 100 times more efficient.
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Phages could replace harmful pesticides with a cleaner, greener alternative
Use of phage therapy in farming could be valuable in replacing chemical pesticides with a safer and greener alternative, helping to address climate change, according to a new review in Sustainable Microbiology.
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Viruses are teeming on your toothbrush and shower head
There’s a jungle of ‘untapped biodiversity’ in the bathroom, a new study finds.
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Bacteria-fighting viruses team up to treat drug-resistant superbugs
Researchers screened a library of bacteriophages to find combinations of the viruses that can work together to fight antibiotic-resistant Klebsiella pneumoniae infections.
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Careers
A fresh perspective on phages - AMI intern Helen Kinchin opens up on her new PhD topic
What’s it like at the start of a career working with bacteriophages? Applied Microbiology International intern Helen Kinchin, who recently began a PhD at the University of Warwick, reveals her experiences.
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Careers
Viruses of Microbes 2024
Discover the benefits of attending a scientific conference. This year, VoM2024 was held in Cairn, Australia.
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New phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
Scientists have developed a technology that lets them edit the genomes of phages in a streamlined and highly effective way, giving them the ability to engineer new phages and study how the viruses can be used to target specific bacteria.
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Dormancy defence systems show us why phages may not be the answer to everything
Toxin/antitoxin defence systems in bacteria need to be better understood if the potential of phage therapy is to be realised, a new review in Sustainable Microbiology suggests.
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Scientists unveil first complete image of the PARIS system
A new study explores the PARIS immune system, which bacteria use to protect themselves against viral infections and which stands for Phage Anti-Restriction Induced System.
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3D shapes of viral proteins point to previously unknown roles
Scientists uncover an ancient immune-evading strategy shared by animal viruses and viruses that infect bacteria; findings may help in the development of new antiviral therapies.
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Infected bacteria fight back with ‘hidden’ genes that halt cell growth, slow viral spread
Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth.
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Coinfecting viruses impede each other’s ability to enter cells
Scientists researching phage infection at the level of a single cell investigated whether the number of infecting phages that bind to the bacterial surface corresponds to the amount of viral genetic material that is injected into the cell.
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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Researchers unveil secrets behind phages’ flawless timing
New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Researchers develop a way to make lifesaving phages accessible, transportable and much easier to use
Researchers have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them.
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Phage-derived enzyme targets biofilms to mitigate acute graft-versus-host disease
Scientists investigating acute graft-versus-host disease probe gut microbiome to detect presence of a bacteriophage-derived enzyme known as endolysin, exhibiting potent antibacterial activity specifically targeting E. faecalis.