All Phage Therapy articles
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NewsNew study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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NewsA review of Clostridioides difficile infection and treatments
<i>Clostridioides difficile</i> is a serious nosocomial infection that could cause from mild diarrhea to fatal colitis. Here presents a general overview that describes the current and emerging treatment practices for the prevention of <i>Clostridioides difficile</i> infection and its recourrences.
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CareersMy autistic academic maze - and my advice to neurodiverse PhD students
In Neurodiversity Celebration Week, PhD student Joshua Yates reveals the challenges of pursuing a career in microbiology with autism and dyslexia - and his advice to others.
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NewsMontana State scientist receives $2.8 million grant to advance Lyme disease research
Funding from the National Institutes of Health will allow a Montana State University research team to deepen explorations into a disease that is posing an increasing threat in the U.S. Lyme disease is a bacterial infection transmitted by ticks.
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NewsNew insights into phage–bacteria interactions in the gut microbiome
Researchers studied the interactions between bacteria and phages within the gut microbiome and highlighted the significance of the phage community to shape the microbiome that contributes to host health and diseases.
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NewsScientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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FeaturesHow phage therapy supports One Health in the AMR fight
In the face of an escalating global health crisis, One Health demonstrates the power of collaborative, multidisciplinary action.
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NewsJumbo phages deploying secret handshakes could usher in new antibiotics
Jumbo phages create a restricted space inside bacteria where they can copy their DNA while surrounded by a protective shield. A new study reveals that the shield works via a set of ’secret handshakes’, allowing only a specific set of useful proteins to pass through.
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NewsNew phage platform pinpoints viruses that can deliver a knockout blow for killer bacteria
An international group of microbial experts has launched a powerful and flexible free online genomic toolkit for more rapid development of phage therapy. They say it is capable of assessing if a phage is suitable for a targeted therapy in under 10 minutes.
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NewsBacteria produce molecules that help viruses infect competing bacteria
In a new study, researchers have discovered a new way that bacteria can kill their competitors in complex microbial communities, revealing novel approaches to leverage viruses to kill harmful bacteria.
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NewsStudy uncovers previously unknown bacterial mode of resistance against viruses
Researchers have discovered a unique mechanism that protects marine bacteria from viruses that attack them.
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NewsNew method detects fecal contamination of water using viral DNA
Researchers have developed a novel MST detection method using CrAss-like phages that is capable of specifically detecting human feces-contaminated water.
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NewsHigh-throughput single-microbe RNA sequencing reveals adaptive state heterogeneity and host-phage activity associations in human gut microbiome
A study uses optimized random primers and a triple-module computational pipeline to analyze bacterial and phage activities in the gut microbiome.
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NewsDiverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.
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CareersVan Hung Vuong Le: my year as a Junior Editor with Letters in Applied Microbiology
One year into our Junior Editor training programme with Letters in Applied Microbiology, Van Hung Vuong Le from the University of Exeter reflects on the experience.
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NewsResearchers develop a simple lab-free test to detect bacteria in fluids from water to urine
A novel new test for bacteria in fluids makes it as easy as observing a colour change to confirm the presence of disease-causing pathogens, promising much easier diagnostic tests and greater food safety.
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NewsA new tool to predict the most effective phage cocktail
Researchers have developed a simple and effective new tool that recommends the best possible phage cocktail for a given patient. Paving the way for personalized phage therapies to treat antibiotic-resistant bacterial infections.
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NewsResearchers hope to develop novel drugs for gastrointestinal disorders by fermenting feces
In a new study, researchers have been cultivating ‘good viruses’ from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants and improve this life-saving treatment through standardization.
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NewsMeet the Global Ambassadors: Our Q&A with Matthew B Sullivan
The Microbiologist chats with our new Global Ambassador for the United States, Matthew B Sullivan, who is Professor of Microbiology and Director of the Center of Microbiome Science, at The Ohio State University.
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NewsStructural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.