All Phage Therapy articles
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News
The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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Researchers release phage images with unprecedented detail
Researchers have produced the most detailed image to date of a bacteriophage, that has allowed them to see for the first time the structural makeup of the part of the phage that directly attaches to its target Mycobacterium cell.
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Phage therapy at a crossroads: global experts gather for ground-breaking 2025 Congress
Global multidisciplinary experts and innovators convene for the 8th World Congress on Targeting Phage Therapy 2025 on June 10-11. This leading event is dedicated to the advancement of bacteriophage science and applications in multiple bioscience areas.
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The first case of phage therapy for biliary tract infection caused by superbugs
A new study reports the first clinical application case of personalized phage therapy for biliary tract infection.
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Virus infects cells with a protective cloaking mechanism
The discovery of a jumbo phage’s stealth compartment could be leveraged to engineer new therapies to treat antibacterial-resistant infections.
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Discovery of bacteria’s defence against viruses becomes piece of the puzzle against resistance
A new study shows that the emergence of resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.
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New study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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A review of Clostridioides difficile infection and treatments
<i>Clostridioides difficile</i> is a serious nosocomial infection that could cause from mild diarrhea to fatal colitis. Here presents a general overview that describes the current and emerging treatment practices for the prevention of <i>Clostridioides difficile</i> infection and its recourrences.
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Careers
My autistic academic maze - and my advice to neurodiverse PhD students
In Neurodiversity Celebration Week, PhD student Joshua Yates reveals the challenges of pursuing a career in microbiology with autism and dyslexia - and his advice to others.
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Montana State scientist receives $2.8 million grant to advance Lyme disease research
Funding from the National Institutes of Health will allow a Montana State University research team to deepen explorations into a disease that is posing an increasing threat in the U.S. Lyme disease is a bacterial infection transmitted by ticks.
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New insights into phage–bacteria interactions in the gut microbiome
Researchers studied the interactions between bacteria and phages within the gut microbiome and highlighted the significance of the phage community to shape the microbiome that contributes to host health and diseases.
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Scientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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Features
How phage therapy supports One Health in the AMR fight
In the face of an escalating global health crisis, One Health demonstrates the power of collaborative, multidisciplinary action.
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Jumbo phages deploying secret handshakes could usher in new antibiotics
Jumbo phages create a restricted space inside bacteria where they can copy their DNA while surrounded by a protective shield. A new study reveals that the shield works via a set of ’secret handshakes’, allowing only a specific set of useful proteins to pass through.
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New phage platform pinpoints viruses that can deliver a knockout blow for killer bacteria
An international group of microbial experts has launched a powerful and flexible free online genomic toolkit for more rapid development of phage therapy. They say it is capable of assessing if a phage is suitable for a targeted therapy in under 10 minutes.
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Bacteria produce molecules that help viruses infect competing bacteria
In a new study, researchers have discovered a new way that bacteria can kill their competitors in complex microbial communities, revealing novel approaches to leverage viruses to kill harmful bacteria.
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Study uncovers previously unknown bacterial mode of resistance against viruses
Researchers have discovered a unique mechanism that protects marine bacteria from viruses that attack them.
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New method detects fecal contamination of water using viral DNA
Researchers have developed a novel MST detection method using CrAss-like phages that is capable of specifically detecting human feces-contaminated water.
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High-throughput single-microbe RNA sequencing reveals adaptive state heterogeneity and host-phage activity associations in human gut microbiome
A study uses optimized random primers and a triple-module computational pipeline to analyze bacterial and phage activities in the gut microbiome.
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Diverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.