All Phage Therapy articles
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News
Diverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.
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Careers
Van Hung Vuong Le: my year as a Junior Editor with Letters in Applied Microbiology
One year into our Junior Editor training programme with Letters in Applied Microbiology, Van Hung Vuong Le from the University of Exeter reflects on the experience.
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Researchers develop a simple lab-free test to detect bacteria in fluids from water to urine
A novel new test for bacteria in fluids makes it as easy as observing a colour change to confirm the presence of disease-causing pathogens, promising much easier diagnostic tests and greater food safety.
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A new tool to predict the most effective phage cocktail
Researchers have developed a simple and effective new tool that recommends the best possible phage cocktail for a given patient. Paving the way for personalized phage therapies to treat antibiotic-resistant bacterial infections.
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Researchers hope to develop novel drugs for gastrointestinal disorders by fermenting feces
In a new study, researchers have been cultivating ‘good viruses’ from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants and improve this life-saving treatment through standardization.
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Meet the Global Ambassadors: Our Q&A with Matthew B Sullivan
The Microbiologist chats with our new Global Ambassador for the United States, Matthew B Sullivan, who is Professor of Microbiology and Director of the Center of Microbiome Science, at The Ohio State University.
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Structural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
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Major antimicrobial power boost as phages form into surprising flower shapes
Researchers treated bacteria-eating viruses so they could be viewed alive under an electron microscope and coaxed them to join together into flower-like shapes - discovering that this made them 100 times more efficient.
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Phages could replace harmful pesticides with a cleaner, greener alternative
Use of phage therapy in farming could be valuable in replacing chemical pesticides with a safer and greener alternative, helping to address climate change, according to a new review in Sustainable Microbiology.
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Viruses are teeming on your toothbrush and shower head
There’s a jungle of ‘untapped biodiversity’ in the bathroom, a new study finds.
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Bacteria-fighting viruses team up to treat drug-resistant superbugs
Researchers screened a library of bacteriophages to find combinations of the viruses that can work together to fight antibiotic-resistant Klebsiella pneumoniae infections.
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Careers
A fresh perspective on phages - AMI intern Helen Kinchin opens up on her new PhD topic
What’s it like at the start of a career working with bacteriophages? Applied Microbiology International intern Helen Kinchin, who recently began a PhD at the University of Warwick, reveals her experiences.
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Careers
Viruses of Microbes 2024
Discover the benefits of attending a scientific conference. This year, VoM2024 was held in Cairn, Australia.
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News
New phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
Scientists have developed a technology that lets them edit the genomes of phages in a streamlined and highly effective way, giving them the ability to engineer new phages and study how the viruses can be used to target specific bacteria.
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Dormancy defence systems show us why phages may not be the answer to everything
Toxin/antitoxin defence systems in bacteria need to be better understood if the potential of phage therapy is to be realised, a new review in Sustainable Microbiology suggests.
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Scientists unveil first complete image of the PARIS system
A new study explores the PARIS immune system, which bacteria use to protect themselves against viral infections and which stands for Phage Anti-Restriction Induced System.
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3D shapes of viral proteins point to previously unknown roles
Scientists uncover an ancient immune-evading strategy shared by animal viruses and viruses that infect bacteria; findings may help in the development of new antiviral therapies.
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Infected bacteria fight back with ‘hidden’ genes that halt cell growth, slow viral spread
Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth.
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Coinfecting viruses impede each other’s ability to enter cells
Scientists researching phage infection at the level of a single cell investigated whether the number of infecting phages that bind to the bacterial surface corresponds to the amount of viral genetic material that is injected into the cell.
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.